ES8705860A1 - Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina - Google Patents
Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidinaInfo
- Publication number
- ES8705860A1 ES8705860A1 ES551777A ES551777A ES8705860A1 ES 8705860 A1 ES8705860 A1 ES 8705860A1 ES 551777 A ES551777 A ES 551777A ES 551777 A ES551777 A ES 551777A ES 8705860 A1 ES8705860 A1 ES 8705860A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- phenylpiperidine
- ethyl
- preparation
- therapeutical use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XRVHXZBVZURDEM-UHFFFAOYSA-N 1-ethyl-3-phenylpiperidin-3-ol Chemical compound C1N(CC)CCCC1(O)C1=CC=CC=C1 XRVHXZBVZURDEM-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO DE PREPARAR DERIVADOS DE 3-HIDROXI-3-FENIL-PIPERIDINA. CONSISTE EN HACER REACCIONAR UN HALOGENURO DE FENILMAGNESIO DE FORMULA C6H5MGX CON UNA 3-PIPERIDINA DE FORMULA (IV), DURANTE 0,25 H A TEMPERATURA ENTRE 0 Y 25JC, BAJO ATMOSFERA DE NITROGENO, EN UN SOLVENTE INERTE TAL COMO DIETILETER, PARA OBTENER DERIVADOS DE 3-HIDROXI-3-FENILPIPERIDINA Y SUS SALES DE ADICION DE FORMULAS (I), (II) O (III), DONDE R ES UN GRUPO ALQUILO DE C 2 A 4. TIENEN APLICACION PARA PREPARAR COMPOSICIONES FARMACEUTICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8501410A FR2576898B1 (fr) | 1985-02-01 | 1985-02-01 | Derives de 3-phenyl-tetrahydropyridine, procede de preparation et utilisation en therapeutique |
FR8510550A FR2584714B1 (fr) | 1985-07-10 | 1985-07-10 | Derives de 3-hydroxy-3-phenylpiperidine, procede de preparation et utilisation en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
ES551777A0 ES551777A0 (es) | 1987-05-16 |
ES8705860A1 true ES8705860A1 (es) | 1987-05-16 |
Family
ID=26224357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES551777A Expired ES8705860A1 (es) | 1985-02-01 | 1986-01-30 | Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina |
Country Status (10)
Country | Link |
---|---|
US (1) | US4680302A (es) |
EP (1) | EP0192522B1 (es) |
JP (1) | JPH0649684B2 (es) |
CA (1) | CA1263659A (es) |
DE (1) | DE3660628D1 (es) |
DK (1) | DK49986A (es) |
ES (1) | ES8705860A1 (es) |
GR (1) | GR860323B (es) |
IE (1) | IE58931B1 (es) |
PT (1) | PT81950B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2703354B1 (fr) * | 1993-03-31 | 1995-06-30 | Lafon Labor | Derives de 1, 2, 5, 6-tetrahydropyridine, leur procede de preparation et leurs applications en therapeutique. |
FR2721514B1 (fr) * | 1994-06-23 | 1996-09-06 | Lafon Labor | Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines. |
US7240408B2 (en) * | 2004-01-14 | 2007-07-10 | Icon Textile Laser Systems, Inc. | Selectivity altering a fiber height in a pile fabric and apparatus |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA672114A (en) * | 1963-10-15 | H. Beckett Arnold | Analgesic compositions | |
US2589943A (en) * | 1941-10-01 | 1952-03-18 | Ferrosan As | 4-aryl-4-acyl-oxy-piperidines |
GB576962A (en) * | 1944-05-05 | 1946-04-29 | Geoffrey Malcolm Badger | New piperidine derivatives |
GB1049564A (en) * | 1964-02-12 | 1966-11-30 | Allen & Hanburys Ltd | Piperidine derivatives |
FR1455825A (fr) * | 1965-02-18 | 1966-05-20 | Degussa | Procédé de préparation de phényl-tétrahydropyridines substituées |
US4263438A (en) * | 1977-09-13 | 1981-04-21 | Pfizer Inc. | 3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics |
FR2496099A1 (fr) * | 1980-12-15 | 1982-06-18 | Roussel Uclaf | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
-
1986
- 1986-01-27 DE DE8686400154T patent/DE3660628D1/de not_active Expired
- 1986-01-27 EP EP86400154A patent/EP0192522B1/fr not_active Expired
- 1986-01-28 IE IE24586A patent/IE58931B1/en not_active IP Right Cessation
- 1986-01-29 US US06/823,595 patent/US4680302A/en not_active Expired - Lifetime
- 1986-01-30 ES ES551777A patent/ES8705860A1/es not_active Expired
- 1986-01-31 JP JP61021094A patent/JPH0649684B2/ja not_active Expired - Fee Related
- 1986-01-31 DK DK49986A patent/DK49986A/da not_active Application Discontinuation
- 1986-01-31 CA CA000500887A patent/CA1263659A/fr not_active Expired
- 1986-01-31 PT PT81950A patent/PT81950B/pt not_active IP Right Cessation
- 1986-02-03 GR GR860323A patent/GR860323B/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK49986D0 (da) | 1986-01-31 |
CA1263659A (fr) | 1989-12-05 |
ES551777A0 (es) | 1987-05-16 |
DK49986A (da) | 1986-08-02 |
GR860323B (en) | 1986-06-04 |
US4680302A (en) | 1987-07-14 |
IE58931B1 (en) | 1993-12-01 |
PT81950A (fr) | 1986-02-01 |
PT81950B (pt) | 1987-12-30 |
EP0192522B1 (fr) | 1988-08-31 |
JPS61183266A (ja) | 1986-08-15 |
JPH0649684B2 (ja) | 1994-06-29 |
IE860245L (en) | 1986-08-01 |
DE3660628D1 (en) | 1988-10-06 |
EP0192522A1 (fr) | 1986-08-27 |
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