ES8609339A1 - Procedimiento de preparacion de un derivado del acido peni- cilanico y sus sales - Google Patents
Procedimiento de preparacion de un derivado del acido peni- cilanico y sus salesInfo
- Publication number
- ES8609339A1 ES8609339A1 ES548296A ES548296A ES8609339A1 ES 8609339 A1 ES8609339 A1 ES 8609339A1 ES 548296 A ES548296 A ES 548296A ES 548296 A ES548296 A ES 548296A ES 8609339 A1 ES8609339 A1 ES 8609339A1
- Authority
- ES
- Spain
- Prior art keywords
- prepn
- salts
- penicillanic acid
- acid deriv
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE UN DERIVADO DEL ACIDO PENICILIANICO Y SUS SALES. COMPRENDE: A) HIDROGENAR AL ACIDO 6,6-DIBROMOPENICILANICO D.F. (II) CON UNA MEZCLA DE POLVO DE CADMIO (CD) Y ACIDO MINERAL COMO ACIDO SULFURICO (H2SO4) O ACIDO CLORHIDRICO (HCL), EN UN SISTEMA DISOLVENTE FORMADO POR AGUA Y UN DISOLVENTE ELEGIDO ENTRE TETRAHIDROFURANO, DIOXANO O ACETATO DE ETILO, ENTRE 0 Y 15JC; B) FILTRAR LA MEZCLA DE REACCION, PARA SEPARAR EL EXCESO DE CD; C) DESTILAR EL LIQUIDO FILTRADO, PARA SEPARAR EL DISOLVENTE Y OBTENER AL ACIDO 1,1-DIOXIDO PENICILANICO D.F. (I); D) NEUTRALIZAR LA SOLUCION DE C) QUE CONTIENE A (I) CON NAOH O KOH; Y E) TRATAR A (I) NEUTRALIZADO CON 2-ETIL-HEXANOATO DE NA O DE K EN ACETATO DE ETILO. SE UTILIZA COMO INHIBIDOR DE B-LACTAMASAS MICROBIANAS.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES548296A ES8609339A1 (es) | 1985-10-29 | 1985-10-29 | Procedimiento de preparacion de un derivado del acido peni- cilanico y sus sales |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES548296A ES8609339A1 (es) | 1985-10-29 | 1985-10-29 | Procedimiento de preparacion de un derivado del acido peni- cilanico y sus sales |
Publications (2)
Publication Number | Publication Date |
---|---|
ES548296A0 ES548296A0 (es) | 1986-04-01 |
ES8609339A1 true ES8609339A1 (es) | 1986-04-01 |
Family
ID=8490046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548296A Expired ES8609339A1 (es) | 1985-10-29 | 1985-10-29 | Procedimiento de preparacion de un derivado del acido peni- cilanico y sus sales |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8609339A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1041075A1 (en) * | 1999-03-03 | 2000-10-04 | Alex-Gyogyszer Kutatási | Procedure for the preparation of dioxopenicillanic acid derivatives |
-
1985
- 1985-10-29 ES ES548296A patent/ES8609339A1/es not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1041075A1 (en) * | 1999-03-03 | 2000-10-04 | Alex-Gyogyszer Kutatási | Procedure for the preparation of dioxopenicillanic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
ES548296A0 (es) | 1986-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted | ||
FD1A | Patent lapsed |
Effective date: 20051219 |