ES8605472A1 - Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona - Google Patents
Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanonaInfo
- Publication number
- ES8605472A1 ES8605472A1 ES546859A ES546859A ES8605472A1 ES 8605472 A1 ES8605472 A1 ES 8605472A1 ES 546859 A ES546859 A ES 546859A ES 546859 A ES546859 A ES 546859A ES 8605472 A1 ES8605472 A1 ES 8605472A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- amino
- methylacetyl
- aminophenyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 1-N-(A-AMINO-A-METILACETIL)-AMINOFENIL-2-AMINO-PROPANONA. CONSISTE EN AMINAR A UN DERIVADO DIHALOGENADO DE FORMULA (II) CON UNA AMINA DE FORMULA (HNRR), EN UNA RELACION I2/1 DE AMINA/DERIVADO HALOGENADO, EN UNAMEZCLA DE ALCOHOL INFERIOR DE C 1 A 3 Y AMINA DE FORMULA (HNRR), A UNA TEMPERATURA ENTRE 15JC Y LA TEMPERATURA DE REFLUJO DEL MEDIO Y DURANTE 1 HORA, PARA OBTENER LAS 1-N-(A-ALQUILAMINO-A-METILACETIL)-AMINOFENIL-2-AMINO-PROPANOS DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS. SIENDO: R, ALQUILO DE C 1 A 4; R, H, O UN GRUPO ALQUILO DE C 1 A 4; Y X, F, CL O BR. SE UTILIZAN COMO AGENTES ANTIDEPRESIVOS PARA EL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8412964A FR2569186B1 (fr) | 1984-08-20 | 1984-08-20 | Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
ES546859A0 ES546859A0 (es) | 1986-03-16 |
ES8605472A1 true ES8605472A1 (es) | 1986-03-16 |
Family
ID=9307108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546859A Expired ES8605472A1 (es) | 1984-08-20 | 1985-08-16 | Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona |
Country Status (13)
Country | Link |
---|---|
US (1) | US4690950A (es) |
EP (1) | EP0174887B1 (es) |
JP (1) | JPS6165855A (es) |
AT (1) | ATE28071T1 (es) |
AU (1) | AU570820B2 (es) |
CA (1) | CA1292015C (es) |
DE (1) | DE3560291D1 (es) |
DK (1) | DK378885A (es) |
ES (1) | ES8605472A1 (es) |
FR (1) | FR2569186B1 (es) |
GR (1) | GR851996B (es) |
PT (1) | PT80992B (es) |
ZA (1) | ZA856150B (es) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2128255A (en) * | 1934-12-22 | 1938-08-30 | Gen Aniline Works Inc | Azo dyestuffs |
DE1015986B (de) * | 1955-07-04 | 1957-09-19 | Thomae Gmbh Dr K | Licht- und Sonnenschutzmittel |
FR1458118A (fr) * | 1964-02-26 | 1966-03-04 | Ciba Geigy | Nouveaux amino-phényl-alcanols et procédé pour leur préparation |
CA1002951A (en) * | 1971-12-13 | 1977-01-04 | Yoshiaki Takebayashi | Anilide derivatives and production thereof |
US4024282A (en) * | 1975-11-25 | 1977-05-17 | Mitsubishi Chemical Industries Ltd. | Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes |
GB1520812A (en) * | 1975-10-02 | 1978-08-09 | Lafon Labor | Benzhydrylsulphinyl derivatives |
GB1531781A (en) * | 1976-03-23 | 1978-11-08 | Lafon Labor | N-propargyl-piperonylamine and its preparation and use |
CA1086733A (en) * | 1976-12-06 | 1980-09-30 | Ryoji Kikumoto | Pharmaceutically active 2-substituted-1-(omega- aminoalkoxy) benzenes |
US4650771A (en) * | 1983-11-04 | 1987-03-17 | Miles Laboratories, Inc. | Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof |
CA1340902C (en) * | 1985-02-15 | 2000-02-22 | Harold L. Kohn | Amino acid derivative anticonvulsant |
-
1984
- 1984-08-20 FR FR8412964A patent/FR2569186B1/fr not_active Expired
-
1985
- 1985-08-07 AT AT85401609T patent/ATE28071T1/de not_active IP Right Cessation
- 1985-08-07 EP EP85401609A patent/EP0174887B1/fr not_active Expired
- 1985-08-07 DE DE8585401609T patent/DE3560291D1/de not_active Expired
- 1985-08-14 ZA ZA856150A patent/ZA856150B/xx unknown
- 1985-08-16 ES ES546859A patent/ES8605472A1/es not_active Expired
- 1985-08-16 CA CA000488854A patent/CA1292015C/en not_active Expired - Lifetime
- 1985-08-16 GR GR851996A patent/GR851996B/el unknown
- 1985-08-16 US US06/766,636 patent/US4690950A/en not_active Expired - Fee Related
- 1985-08-20 DK DK378885A patent/DK378885A/da unknown
- 1985-08-20 JP JP60183804A patent/JPS6165855A/ja active Pending
- 1985-08-20 PT PT80992A patent/PT80992B/pt not_active IP Right Cessation
- 1985-08-20 AU AU46464/85A patent/AU570820B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
GR851996B (es) | 1985-12-17 |
ES546859A0 (es) | 1986-03-16 |
EP0174887A1 (fr) | 1986-03-19 |
ZA856150B (en) | 1986-04-30 |
CA1292015C (en) | 1991-11-12 |
EP0174887B1 (fr) | 1987-07-01 |
AU570820B2 (en) | 1988-03-24 |
DK378885A (da) | 1986-02-21 |
DE3560291D1 (en) | 1987-08-06 |
FR2569186A1 (fr) | 1986-02-21 |
DK378885D0 (da) | 1985-08-20 |
ATE28071T1 (de) | 1987-07-15 |
FR2569186B1 (fr) | 1986-09-05 |
PT80992A (fr) | 1985-09-01 |
AU4646485A (en) | 1986-02-27 |
US4690950A (en) | 1987-09-01 |
JPS6165855A (ja) | 1986-04-04 |
PT80992B (pt) | 1987-09-30 |
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