ES8604420A1 - Procedimiento de preparacion de 2-aminoetilen-1,3-indanodio-nas sustituidas sobre el nitrogeno - Google Patents

Procedimiento de preparacion de 2-aminoetilen-1,3-indanodio-nas sustituidas sobre el nitrogeno

Info

Publication number
ES8604420A1
ES8604420A1 ES545422A ES545422A ES8604420A1 ES 8604420 A1 ES8604420 A1 ES 8604420A1 ES 545422 A ES545422 A ES 545422A ES 545422 A ES545422 A ES 545422A ES 8604420 A1 ES8604420 A1 ES 8604420A1
Authority
ES
Spain
Prior art keywords
aminomethylene
diones
indane
substituted
nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545422A
Other languages
English (en)
Other versions
ES545422A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortial SA filed Critical Cortial SA
Publication of ES8604420A1 publication Critical patent/ES8604420A1/es
Publication of ES545422A0 publication Critical patent/ES545422A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE 2-AMINOETILEN-1,3-INDANODIONAS SUSTITUIDAS SOBRE EL NITROGENO. CONSISTE EN HACER REACCIONAR A LA 2-FORMIL-1,3-INDANODIONA CON UNA AMINA DE FORMULA (NH-R1R2), EN PRESENCIA DE UN ACEPTOR DE HIDRACIDO COMO CARBONATO SODICO, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R1, H O UN GRUPO ALQUILO INFERIOR COMO METILO O ETILO; R2 UN CICLOPROPILMETILO, 2-FENILMETILO, BENCILO, ISOBUTILO Y OTROS; NR1R2 UN HETEROCICLO NITROGENADO DE FORMULA (II); Y N 4, 5 O 6. SE UTILIZAN EN TERAPEUTICA HUMANA Y VETERINARIA POR SUS PROPIEDADES ANTIINFLAMATORIAS, DIURETICAS, BRONCODILATADORAS, ANTICOLINERGICAS, ANTIESPAMODICAS Y ANTIDEPRESIVAS.
ES545422A 1984-07-20 1985-07-19 Procedimiento de preparacion de 2-aminoetilen-1,3-indanodio-nas sustituidas sobre el nitrogeno Expired ES8604420A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8411678A FR2567754B1 (fr) 1984-07-20 1984-07-20 Application therapeutique d'aminomethylene-2 indanediones-1,3 substituees sur l'azote

Publications (2)

Publication Number Publication Date
ES8604420A1 true ES8604420A1 (es) 1986-02-01
ES545422A0 ES545422A0 (es) 1986-02-01

Family

ID=9306403

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545422A Expired ES8604420A1 (es) 1984-07-20 1985-07-19 Procedimiento de preparacion de 2-aminoetilen-1,3-indanodio-nas sustituidas sobre el nitrogeno

Country Status (11)

Country Link
US (2) US4758561A (es)
EP (1) EP0172128B1 (es)
JP (1) JPS6144812A (es)
CA (1) CA1266438A (es)
DE (1) DE3571128D1 (es)
ES (1) ES8604420A1 (es)
FR (1) FR2567754B1 (es)
MA (1) MA20491A1 (es)
OA (1) OA08067A (es)
PT (1) PT80830B (es)
ZA (1) ZA855462B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648381A (en) * 1992-04-03 1997-07-15 Innothera Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof
US6231594B1 (en) 1999-08-11 2001-05-15 Radiant Medical, Inc. Method of controlling body temperature while reducing shivering
US6306403B1 (en) * 2000-06-14 2001-10-23 Allergan Sales, Inc. Method for treating parkinson's disease with a botulinum toxin
US6582457B2 (en) 2001-02-15 2003-06-24 Radiant Medical, Inc. Method of controlling body temperature while reducing shivering

Also Published As

Publication number Publication date
ZA855462B (en) 1986-03-26
US4758561A (en) 1988-07-19
CA1266438A (en) 1990-03-06
DE3571128D1 (en) 1989-07-27
MA20491A1 (fr) 1986-04-01
EP0172128A1 (fr) 1986-02-19
EP0172128B1 (fr) 1989-06-21
PT80830B (pt) 1987-09-30
FR2567754A1 (fr) 1986-01-24
JPS6144812A (ja) 1986-03-04
US4757067A (en) 1988-07-12
PT80830A (fr) 1985-08-01
OA08067A (fr) 1987-03-31
FR2567754B1 (fr) 1987-05-29
ES545422A0 (es) 1986-02-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603