ES8603910A1 - Hydroxy-benzoic ester of chloro-pregnane steroid - Google Patents
Hydroxy-benzoic ester of chloro-pregnane steroidInfo
- Publication number
- ES8603910A1 ES8603910A1 ES538694A ES538694A ES8603910A1 ES 8603910 A1 ES8603910 A1 ES 8603910A1 ES 538694 A ES538694 A ES 538694A ES 538694 A ES538694 A ES 538694A ES 8603910 A1 ES8603910 A1 ES 8603910A1
- Authority
- ES
- Spain
- Prior art keywords
- chloro
- ester
- hydroxy
- steroid
- benzoic ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
A polyhydroxyl steroid of pregnane series, 9alpha-chloro 11beta,17alpha,21-trihydroxy 16beta-methyl 1,4-pregnadien-3,20-dione of formula (I) is reacted with a light molar excess of methanosulphonyl chloride in dioxane/pyridine medium at -10 to -2 deg.C for 1-2 h. to obtain the 21-methawsulphonate ester. This is isolated by pouring onto water and ice and crystallised from a strongly-polar solvent, e.g. acetone, ethyl acetate or ether, until the melting range is below 2 deg.C it is used as an intermediate for prepn. of the 21-(2-hydroxy benzoate) ester.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES538694A ES8603910A1 (en) | 1984-12-17 | 1984-12-17 | Hydroxy-benzoic ester of chloro-pregnane steroid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES538694A ES8603910A1 (en) | 1984-12-17 | 1984-12-17 | Hydroxy-benzoic ester of chloro-pregnane steroid |
Publications (2)
Publication Number | Publication Date |
---|---|
ES538694A0 ES538694A0 (en) | 1986-01-01 |
ES8603910A1 true ES8603910A1 (en) | 1986-01-01 |
Family
ID=8488335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES538694A Expired ES8603910A1 (en) | 1984-12-17 | 1984-12-17 | Hydroxy-benzoic ester of chloro-pregnane steroid |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8603910A1 (en) |
-
1984
- 1984-12-17 ES ES538694A patent/ES8603910A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES538694A0 (en) | 1986-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20051005 |