ES8603910A1 - Hydroxy-benzoic ester of chloro-pregnane steroid - Google Patents

Hydroxy-benzoic ester of chloro-pregnane steroid

Info

Publication number
ES8603910A1
ES8603910A1 ES538694A ES538694A ES8603910A1 ES 8603910 A1 ES8603910 A1 ES 8603910A1 ES 538694 A ES538694 A ES 538694A ES 538694 A ES538694 A ES 538694A ES 8603910 A1 ES8603910 A1 ES 8603910A1
Authority
ES
Spain
Prior art keywords
chloro
ester
hydroxy
steroid
benzoic ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538694A
Other languages
Spanish (es)
Other versions
ES538694A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Priority to ES538694A priority Critical patent/ES8603910A1/en
Publication of ES538694A0 publication Critical patent/ES538694A0/en
Publication of ES8603910A1 publication Critical patent/ES8603910A1/en
Expired legal-status Critical Current

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  • Steroid Compounds (AREA)

Abstract

A polyhydroxyl steroid of pregnane series, 9alpha-chloro 11beta,17alpha,21-trihydroxy 16beta-methyl 1,4-pregnadien-3,20-dione of formula (I) is reacted with a light molar excess of methanosulphonyl chloride in dioxane/pyridine medium at -10 to -2 deg.C for 1-2 h. to obtain the 21-methawsulphonate ester. This is isolated by pouring onto water and ice and crystallised from a strongly-polar solvent, e.g. acetone, ethyl acetate or ether, until the melting range is below 2 deg.C it is used as an intermediate for prepn. of the 21-(2-hydroxy benzoate) ester.
ES538694A 1984-12-17 1984-12-17 Hydroxy-benzoic ester of chloro-pregnane steroid Expired ES8603910A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES538694A ES8603910A1 (en) 1984-12-17 1984-12-17 Hydroxy-benzoic ester of chloro-pregnane steroid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES538694A ES8603910A1 (en) 1984-12-17 1984-12-17 Hydroxy-benzoic ester of chloro-pregnane steroid

Publications (2)

Publication Number Publication Date
ES538694A0 ES538694A0 (en) 1986-01-01
ES8603910A1 true ES8603910A1 (en) 1986-01-01

Family

ID=8488335

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538694A Expired ES8603910A1 (en) 1984-12-17 1984-12-17 Hydroxy-benzoic ester of chloro-pregnane steroid

Country Status (1)

Country Link
ES (1) ES8603910A1 (en)

Also Published As

Publication number Publication date
ES538694A0 (en) 1986-01-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051005