ES8603395A1 - N-(3-phenylmethylthio-1-oxo-propyl)-amino-acetic-acid derivatives, their preparation and their therapeutical use. - Google Patents

N-(3-phenylmethylthio-1-oxo-propyl)-amino-acetic-acid derivatives, their preparation and their therapeutical use.

Info

Publication number
ES8603395A1
ES8603395A1 ES542379A ES542379A ES8603395A1 ES 8603395 A1 ES8603395 A1 ES 8603395A1 ES 542379 A ES542379 A ES 542379A ES 542379 A ES542379 A ES 542379A ES 8603395 A1 ES8603395 A1 ES 8603395A1
Authority
ES
Spain
Prior art keywords
phenylmethylthio
oxo
acetic
propyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES542379A
Other languages
Spanish (es)
Other versions
ES542379A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8406200A external-priority patent/FR2563218B1/en
Priority claimed from FR8406201A external-priority patent/FR2563219B1/en
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES8603395A1 publication Critical patent/ES8603395A1/en
Publication of ES542379A0 publication Critical patent/ES542379A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds corresponding to the general formula I < IMAGE > in which R1 denotes one or two halogen atoms, one or two CH3 groups, a CF3, OCH3, CN, NO2, CONH2 or COC6H5 group, a condensed benzo nucleus or, when R2 is a (3-indolyl)methyl or CH2CH2SCH3 group, a hydrogen atom, and R2 denotes a hydrogen atom or a C1-4 alkyl, a CH2CONH2, CH2CH2CONH2, CH2CH2SCH3, CH2C6H5 or CH2C6H4OH group or a (3-indolyl)methyl group.
ES542379A 1984-04-19 1985-04-18 "PROCEDURE TO PREPARE ACID DERIVATIVES N- (FENILME- TILTIO-3-OXO-1-PROPIL) -AMINOACETIC". Granted ES542379A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8406200A FR2563218B1 (en) 1984-04-19 1984-04-19 N - ((CHLORO-2 PHENYL) METHYLTHIO-3 OXO-1 PROPYL) -AMINOACETIC ACID DERIVATIVES SUBSTITUTED IN A, THEIR PREPARATION AND THERAPEUTIC APPLICATION
FR8406201A FR2563219B1 (en) 1984-04-19 1984-04-19 N- (PHENYLMETHYLTHIO-3 OXO-1 PROPYL) ACID DERIVATIVES - AMINOACETIC, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
ES8603395A1 true ES8603395A1 (en) 1985-12-16
ES542379A0 ES542379A0 (en) 1985-12-16

Family

ID=26223924

Family Applications (1)

Application Number Title Priority Date Filing Date
ES542379A Granted ES542379A0 (en) 1984-04-19 1985-04-18 "PROCEDURE TO PREPARE ACID DERIVATIVES N- (FENILME- TILTIO-3-OXO-1-PROPIL) -AMINOACETIC".

Country Status (10)

Country Link
EP (1) EP0161172A1 (en)
AU (1) AU4138685A (en)
DK (1) DK174885A (en)
ES (1) ES542379A0 (en)
FI (1) FI851550L (en)
GR (1) GR850951B (en)
HU (1) HUT38094A (en)
IL (1) IL74956A0 (en)
NO (1) NO851546L (en)
PT (1) PT80316B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU595193B2 (en) * 1985-04-19 1990-03-29 Smithkline Beckman Corporation Thio substituted acidic derivatives
US5196563A (en) * 1986-12-17 1993-03-23 Ciba-Geigy Corporation N-phenyl-N-carboxythioureas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451186A (en) * 1961-11-02 1968-05-15 Santen Phamarceutical Co Ltd Process for the preparation of N-mercaptopropionylglycine and its derivatives
JPS535112A (en) * 1976-03-08 1978-01-18 Santen Pharmaceutical Co Ltd New cysteine derivatives
IT1111384B (en) * 1978-12-21 1986-01-13 Sigma Tau Ind Farmaceuti GUAIACYL ESTERS OF MERCAPTOPROPIONIC ACID DERIVATIVES PROCEDURE FOR THEIR PREPARATION AND THERAPEUTIC USE

Also Published As

Publication number Publication date
PT80316A (en) 1985-05-01
FI851550A0 (en) 1985-04-18
NO851546L (en) 1985-10-21
DK174885D0 (en) 1985-04-18
HUT38094A (en) 1986-04-28
GR850951B (en) 1985-11-25
DK174885A (en) 1985-10-20
ES542379A0 (en) 1985-12-16
AU4138685A (en) 1985-10-24
IL74956A0 (en) 1985-08-30
PT80316B (en) 1987-02-16
FI851550L (en) 1985-10-20
EP0161172A1 (en) 1985-11-13

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