ES8601202A1 - Procedimiento para la produccion de espirosuccinimidas - Google Patents
Procedimiento para la produccion de espirosuccinimidasInfo
- Publication number
- ES8601202A1 ES8601202A1 ES533735A ES533735A ES8601202A1 ES 8601202 A1 ES8601202 A1 ES 8601202A1 ES 533735 A ES533735 A ES 533735A ES 533735 A ES533735 A ES 533735A ES 8601202 A1 ES8601202 A1 ES 8601202A1
- Authority
- ES
- Spain
- Prior art keywords
- production
- spiroxuccinimides
- utilization
- compounds
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO PARA LA PRODUCCION DE ESPIROSUCCINIMIDAS. CONSISTE EN OXIDAR UN COMPUESTO DE FORMULA (II) O UNA SAL DE ADICION DE ACIDOS CON PEROXIDO DE HIDROGENO O PERACIDOS ORGANICOS COMO CLOROPERBENZOICO PARA OBTENER UN COMPUESTO DE FORMULA (I) Y LAS SALES DE ADICION DE ACIDO. SIENDO: R1 H ALQUILO DE C 1 A 6 ALQUILO DE C 1 A 6 SUSTITUIDO POR HAL 1 A 6 Y OTROS; R2 H ALQUILO DE C 1 A 6 Y OTROS; R3 H ALQUILO DE C 1 A 4 Y OTROS; R4 Y R5 INDEPENDIENTEMENTE H O ALQUILO DE C 1 A 4; X1 Y X2 INDEPENDIENTEMENTE O O S; M Y N INDEPENDIENTEMENTE 1 2 3 O 4 SIEMPRE QUE M B /H 6. SE UTILIZA PARA EL TRATAMIENTO DE LA DEMENCIA SENIL LA MANIA Y LA HIPERCINESIA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH350483 | 1983-06-27 | ||
CH350583 | 1983-06-27 | ||
CH350383 | 1983-06-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES533735A0 ES533735A0 (es) | 1985-10-16 |
ES8601202A1 true ES8601202A1 (es) | 1985-10-16 |
Family
ID=27174377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES533735A Expired ES8601202A1 (es) | 1983-06-27 | 1984-06-26 | Procedimiento para la produccion de espirosuccinimidas |
Country Status (16)
Country | Link |
---|---|
AU (1) | AU2983384A (es) |
DE (1) | DE3422411A1 (es) |
DK (1) | DK310184A (es) |
ES (1) | ES8601202A1 (es) |
FI (1) | FI842547A (es) |
FR (1) | FR2549061A1 (es) |
GB (1) | GB2142332A (es) |
GR (1) | GR82274B (es) |
HU (1) | HUT36793A (es) |
IL (1) | IL72218A0 (es) |
IT (1) | IT1199148B (es) |
LU (1) | LU85434A1 (es) |
NL (1) | NL8401907A (es) |
PT (1) | PT78787B (es) |
SE (1) | SE8403376L (es) |
WO (1) | WO1985000171A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3431195A1 (de) * | 1984-08-24 | 1986-03-06 | Troponwerke GmbH & Co KG, 5000 Köln | Neue benzodiazepine, verfahren zu ihrer herstellung sowie ihre verwendung |
EP0273659A1 (en) * | 1986-12-27 | 1988-07-06 | Takeda Chemical Industries, Ltd. | Azaspiro compounds, their production and use |
US5407938A (en) * | 1990-04-10 | 1995-04-18 | Israel Institute For Biological Research | Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines) |
JP2800953B2 (ja) * | 1990-07-06 | 1998-09-21 | 住友製薬株式会社 | 新規なイミド誘導体 |
BE1007765A5 (fr) | 1994-06-27 | 1995-10-17 | Blagden Ind Plc | Fut metallique a ouverture totale. |
AU2206699A (en) * | 1997-12-23 | 1999-07-12 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions |
JP4749715B2 (ja) | 2002-07-05 | 2011-08-17 | ターガセプト,インコーポレイテッド | N−アリールジアザスピロ環式化合物、並びにその製造及び使用方法 |
ATE521610T1 (de) | 2003-09-10 | 2011-09-15 | Virochem Pharma Inc | Spiroverbindungen und -verfahren zur modulation von chemokin-rezeptor-aktivität |
US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
US8257680B1 (en) | 2004-02-24 | 2012-09-04 | The General Hospital Corporation | Catalytic radiofluorination |
JO2676B1 (en) | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
EA014239B1 (ru) | 2005-03-08 | 2010-10-29 | Янссен Фармацевтика Н.В. | Производные диаза-спиро-[4,4]нонана в качестве антагонистов нейрокинина (nk1) |
MX2010010314A (es) * | 2008-03-21 | 2011-04-12 | Gen Hospital Corp | Compuestos y composiciones para la deteccion y el tratamiento de la enfermedad de alzheimer y trastornos relacionados. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1211646B (de) * | 1959-03-25 | 1966-03-03 | Sandoz Ag | Verfahren zur Herstellung von Spirosuccinimiden und deren Salzen |
GB936477A (en) * | 1959-03-25 | 1963-09-11 | Sandoz Ltd | Improvements in or relating to substituted succinimides |
US3198800A (en) * | 1964-05-07 | 1965-08-03 | Sandoz Ltd | 2, 8-(para-f-4-oxo-butyl)-diazaspiro[4, 5]-decane-1, 3-diones |
BE897058A (fr) * | 1982-06-25 | 1983-12-16 | Sandoz Sa | Utilisation d'un derive du spiro-succinimide dans le traitement de la demence du type alzheimer |
-
1984
- 1984-06-15 HU HU842326A patent/HUT36793A/hu unknown
- 1984-06-15 NL NL8401907A patent/NL8401907A/nl not_active Application Discontinuation
- 1984-06-16 DE DE3422411A patent/DE3422411A1/de not_active Withdrawn
- 1984-06-18 WO PCT/CH1984/000099 patent/WO1985000171A1/de unknown
- 1984-06-22 FR FR8410017A patent/FR2549061A1/fr active Pending
- 1984-06-25 PT PT78787A patent/PT78787B/pt unknown
- 1984-06-25 GB GB08416172A patent/GB2142332A/en not_active Withdrawn
- 1984-06-25 IL IL72218A patent/IL72218A0/xx unknown
- 1984-06-25 SE SE8403376A patent/SE8403376L/xx not_active Application Discontinuation
- 1984-06-25 DK DK310184A patent/DK310184A/da not_active Application Discontinuation
- 1984-06-25 FI FI842547A patent/FI842547A/fi not_active Application Discontinuation
- 1984-06-25 AU AU29833/84A patent/AU2983384A/en not_active Abandoned
- 1984-06-25 GR GR75100A patent/GR82274B/el unknown
- 1984-06-26 ES ES533735A patent/ES8601202A1/es not_active Expired
- 1984-06-26 IT IT48458/84A patent/IT1199148B/it active
- 1984-06-27 LU LU85434A patent/LU85434A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
PT78787B (en) | 1986-06-05 |
FI842547A0 (fi) | 1984-06-25 |
ES533735A0 (es) | 1985-10-16 |
HUT36793A (en) | 1985-10-28 |
NL8401907A (nl) | 1985-01-16 |
WO1985000171A1 (en) | 1985-01-17 |
GR82274B (es) | 1984-12-13 |
SE8403376D0 (sv) | 1984-06-25 |
DK310184A (da) | 1984-12-28 |
FI842547A (fi) | 1984-12-28 |
FR2549061A1 (fr) | 1985-01-18 |
IT1199148B (it) | 1988-12-30 |
GB8416172D0 (en) | 1984-08-01 |
LU85434A1 (fr) | 1985-03-26 |
IT8448458A0 (it) | 1984-06-26 |
GB2142332A (en) | 1985-01-16 |
IL72218A0 (en) | 1984-10-31 |
DK310184D0 (da) | 1984-06-25 |
PT78787A (en) | 1984-07-01 |
AU2983384A (en) | 1985-01-03 |
DE3422411A1 (de) | 1985-01-03 |
SE8403376L (sv) | 1984-12-28 |
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