ES8601146A1 - Azole derivatives process for their production compositions containing them and their use - Google Patents

Azole derivatives process for their production compositions containing them and their use

Info

Publication number
ES8601146A1
ES8601146A1 ES536138A ES536138A ES8601146A1 ES 8601146 A1 ES8601146 A1 ES 8601146A1 ES 536138 A ES536138 A ES 536138A ES 536138 A ES536138 A ES 536138A ES 8601146 A1 ES8601146 A1 ES 8601146A1
Authority
ES
Spain
Prior art keywords
hydrogen
halogen
compositions containing
azole derivatives
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536138A
Other languages
Spanish (es)
Other versions
ES536138A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8601146A1 publication Critical patent/ES8601146A1/en
Publication of ES536138A0 publication Critical patent/ES536138A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

A compound of formula I < IMAGE > wherein R1 and R2, independently, are hydrogen, halogen, nitro or unsubstituted or mono- or poly-halogen substituted lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy or lower alkylthio or unsubstituted or substituted phenyl or phenoxy, R3 is hydrogen or lower alkyl, R4 and R5, independently, are hydrogen or halogen, Y is CH or N, A is a C2-7methylene bridge and n is 0 or 1, in free base form or in the form of an acid addition salt or a physiologically-hydrolysable and -acceptable derivative, which compounds are indicated for use as chemotherapeutic agents e.g. as anti-mycotics and in addition as fungicides.
ES536138A 1983-09-22 1984-09-21 PROCEDURE FOR PREPARING AZOLIC DERIVATIVES Granted ES536138A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH515683 1983-09-22
CH634983 1983-11-28

Publications (2)

Publication Number Publication Date
ES8601146A1 true ES8601146A1 (en) 1985-11-01
ES536138A0 ES536138A0 (en) 1985-11-01

Family

ID=25697104

Family Applications (1)

Application Number Title Priority Date Filing Date
ES536138A Granted ES536138A0 (en) 1983-09-22 1984-09-21 PROCEDURE FOR PREPARING AZOLIC DERIVATIVES

Country Status (14)

Country Link
AU (1) AU3339884A (en)
BE (1) BE900594A (en)
DE (1) DE3433553A1 (en)
DK (1) DK450784A (en)
ES (1) ES536138A0 (en)
FI (1) FI843692L (en)
FR (1) FR2552431A1 (en)
GB (1) GB2146987A (en)
IL (1) IL73008A0 (en)
IT (1) IT1199193B (en)
LU (1) LU85551A1 (en)
NL (1) NL8402755A (en)
PT (1) PT79240B (en)
SE (1) SE8404712L (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8429932D0 (en) * 1984-11-27 1985-01-03 Pfizer Ltd Triazole antifungal agents
DE3608792A1 (en) * 1986-03-15 1987-09-24 Hoechst Ag 1,1-DISUBSTITUTED CYCLOPROPANE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
DE3784787T2 (en) * 1986-06-23 1994-01-20 Du Pont Merck Pharma Fungicidal carbinols.
US4952232A (en) * 1987-04-29 1990-08-28 E. I. Du Pont De Nemours And Company Antifungal carbinols
US4980367A (en) * 1987-12-17 1990-12-25 E. I. Du Pont De Nemours And Company Antifungal carbinols
US4965281A (en) * 1986-06-23 1990-10-23 E. I. Du Pont De Nemours And Cmopany Antifungal carbinols
US5084465A (en) * 1986-06-23 1992-01-28 Du Pont Merck Pharmaceutical Company Antifungal carbinols
DE3644615A1 (en) * 1986-12-29 1988-07-07 Lentia Gmbh IMIDAZOLE AND TRIAZOLE DERIVATIVES FOR USE AS AN ANTIMYCOTIC AGENTS
US5268517A (en) * 1989-07-14 1993-12-07 Basf Aktiengesellschaft Stereoselective preparation of Z-1,2-diarylallyl chlorides and the conversion thereof into azolylmethyloxiranes, and novel intermediates
JP2975058B2 (en) * 1989-07-18 1999-11-10 ビーエーエスエフ アクチェンゲゼルシャフト Novel Z-1,2-diaryl-allyl chloride, method for its configuration-selective preparation and novel chloromethyl-diaryl-oxirane prepared therefrom
WO2003059899A1 (en) 2002-01-14 2003-07-24 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof
UA80120C2 (en) 2002-03-26 2007-08-27 Boehringer Ingelheim Pharma Glucocorticoid mimetics, pharmaceutical composition based thereon
AU2003230700A1 (en) 2002-03-26 2003-10-13 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
CA2496175A1 (en) 2002-08-21 2004-03-04 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted hihydroquinolines as glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7579469B2 (en) 2003-01-03 2009-08-25 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
UY28526A1 (en) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma GLUCOCORTICOID MIMETICS, METHODS OF PREPARATION PHARMACEUTICAL COMPOSITIONS AND USES OF THE SAME
ATE366726T1 (en) 2003-10-16 2007-08-15 Boehringer Ingelheim Pharma STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
ATE433958T1 (en) 2004-12-27 2009-07-15 Boehringer Ingelheim Pharma GLUCOCORTICOID MIMETICS, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF
BRPI0720131A2 (en) 2006-12-06 2014-02-04 Boehringer Ingelheim Int MIMETIC GLYCORTICOIDS, METHODS FOR MAKING THEM, PHARMACEUTICAL COMPOSITIONS AND USES OF THE SAME.
DK2300472T3 (en) 2008-06-06 2012-04-10 Boehringer Ingelheim Int Glucocorticoid mimetics, methods of their preparation, pharmaceutical compositions and uses thereof
US20090312558A1 (en) * 2008-06-13 2009-12-17 Reliance Life Sciences Pvt. Ltd. Process for the preparation of arylcyclopropoane carboxylic carbonitriles, and compounds derived therefrom

Also Published As

Publication number Publication date
SE8404712D0 (en) 1984-09-20
GB2146987A (en) 1985-05-01
LU85551A1 (en) 1985-04-29
FI843692A0 (en) 1984-09-20
PT79240A (en) 1984-10-01
FR2552431A1 (en) 1985-03-29
DE3433553A1 (en) 1985-04-11
GB8423710D0 (en) 1984-10-24
NL8402755A (en) 1985-04-16
PT79240B (en) 1986-08-08
FI843692L (en) 1985-03-23
IT8448889A0 (en) 1984-09-21
DK450784A (en) 1985-03-23
ES536138A0 (en) 1985-11-01
SE8404712L (en) 1985-03-23
AU3339884A (en) 1985-03-28
BE900594A (en) 1985-03-18
IT8448889A1 (en) 1986-03-21
IL73008A0 (en) 1984-12-31
IT1199193B (en) 1988-12-30
DK450784D0 (en) 1984-09-20

Similar Documents

Publication Publication Date Title
ES8601146A1 (en) Azole derivatives process for their production compositions containing them and their use
ES8401031A1 (en) N-(3-substituted aminophenyl) tetrahydrophthalimides and herbicidal composition.
IL93443A0 (en) Trifluoromethylphenylazolyl-methyloxirane derivatives and fungicides containing these compounds
ES8700228A1 (en) Substituted propargyloxyacetonitrile derivatives, process for production thereof, and herbicide and agricultural-horticultural fungicide comprising said derivatives as active ingredients.
ES269967A1 (en) Pyrazolones and processes for their preparation
ES8402581A1 (en) Fungicidal heterocyclic compounds and compositions containing them.
ES8702378A1 (en) N-substituted triazole derivatives, and their production and use.
ES8306374A1 (en) Heterocyclic phenyl ethers, process for their preparation and herbicides containing them.
ATE75737T1 (en) INDENOTHIAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION.
MY109714A (en) Process for preparing 8-chloroquinolone derivatives
ES8100802A1 (en) Azolyl ketals, process for producing them, and their use as microbicides
DE3174132D1 (en) New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof
ATE30718T1 (en) PREPARATION OF 1-BENZYL AZETIDIN-3-OL AND THE CORRESPONDING HALID ACID.
IL70354A0 (en) Substituted benzylcycloalkenylurea derivatives,their preparation and their use as fungicides
ES8107242A1 (en) Phosphoric acid derivatives from N-phenyl N-(alkoxycarbonylalkyl)acetamides, process for preparing them and fungicidal compositions containing them.
PT84367A (en) Process for the preparation of a fungicidal compound containing a naphthimidezolone
ES478110A1 (en) 3-Azabicyclo(3.1.0)hexane derivatives, a process for their preparation, biologically active compositions containing them and herbicidal method using them.
ES8403891A1 (en) Furyloxazolylacetic acid derivatives, process for preparing same and pharmaceutical compositions containing same.
ES8307233A1 (en) Derivatives of 1,4-thiazane-carboxylic acid, preparation and utilization thereof and compositions containing same
ES8506702A1 (en) Furyloxazolylacetic acid derivative, processes for preparing same and pharmaceutical composition.
ATE17851T1 (en) IMIDAZOLYLCARBONIC ACIDS, THEIR DERIVATIVES AND PRODUCTION.
ES8703457A1 (en) Novel thioketene derivatives and process for the preparation thereof.
ES8606245A1 (en) Herbicidal Substituted Phenoxyanilines and Pyridyloxyanilines
ES2044883T3 (en) PROCEDURE FOR PREPARING REPLACED QUINOXALINS.
ES8601147A1 (en) Aminoethylimidazole, pharmaceutical composition containing them and process for their preparation.