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Laboratorios Rubio SA
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Laboratorios Rubio SA
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Priority to ES528242ApriorityCriticalpatent/ES8506624A1/en
Publication of ES528242A0publicationCriticalpatent/ES528242A0/en
Publication of ES8506624A1publicationCriticalpatent/ES8506624A1/en
N-(2-piperidyl methyl) 2,5-bis(2,2,2-trifluoroethoxy) benzamide mono-acetate of formula (III) is prepd. by (a) subjecting 2,5-bis(2,2,2-trifluoroethoxy) benzamide of formula (I) to reductive N-alkylation with 2-diethoxymethyl pyridine of formula (II), and (b) catalytically hydrogenating the pyridine ring in presence of acetic acid.