ES8506307A1 - Un procedimiento para preparar derivados de benzotiazina - Google Patents

Un procedimiento para preparar derivados de benzotiazina

Info

Publication number
ES8506307A1
ES8506307A1 ES530855A ES530855A ES8506307A1 ES 8506307 A1 ES8506307 A1 ES 8506307A1 ES 530855 A ES530855 A ES 530855A ES 530855 A ES530855 A ES 530855A ES 8506307 A1 ES8506307 A1 ES 8506307A1
Authority
ES
Spain
Prior art keywords
benzothiazine
isoxazolyl
carboxamide
hydroxy
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530855A
Other languages
English (en)
Other versions
ES530855A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES530855A0 publication Critical patent/ES530855A0/es
Publication of ES8506307A1 publication Critical patent/ES8506307A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE BENZOTIAZINA Y DE SUS SALES DE METAL O DE AMINA FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1, R2 Y Z PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE R4 ES ALQUILO DE 1 A 4 ATOMOS DE CARBONO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION DE CONDENSACION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A LA TEMPERATURA DE EBULLICION DEL DISOLVENTE.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIINFLAMATORIOS, ANTIPIRETICOS Y ANALGESICOS.
ES530855A 1983-03-23 1984-03-22 Un procedimiento para preparar derivados de benzotiazina Expired ES8506307A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47801683A 1983-03-23 1983-03-23
US06/575,411 US4489077A (en) 1983-03-23 1984-02-02 3-Isoxa-zolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides

Publications (2)

Publication Number Publication Date
ES530855A0 ES530855A0 (es) 1985-07-01
ES8506307A1 true ES8506307A1 (es) 1985-07-01

Family

ID=27045759

Family Applications (2)

Application Number Title Priority Date Filing Date
ES530855A Expired ES8506307A1 (es) 1983-03-23 1984-03-22 Un procedimiento para preparar derivados de benzotiazina
ES538032A Expired ES8601936A1 (es) 1983-03-23 1984-11-28 Un procedimiento para preparar derivados de isoxazolamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES538032A Expired ES8601936A1 (es) 1983-03-23 1984-11-28 Un procedimiento para preparar derivados de isoxazolamina.

Country Status (8)

Country Link
US (1) US4489077A (es)
EP (1) EP0123418B1 (es)
AU (1) AU562834B2 (es)
CA (1) CA1229599A (es)
DE (1) DE3468876D1 (es)
DK (1) DK118884A (es)
ES (2) ES8506307A1 (es)
GR (1) GR81482B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030063046A (ko) * 2002-01-22 2003-07-28 주식회사 엘지생명과학 엘비84068을 함유하는 염증으로 인한 질환의 예방 및치료용 조성물 및 이를 포함하는 제제
DOP2003000641A (es) * 2002-05-10 2003-11-15 Pfizer Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
KR100568191B1 (ko) * 2002-08-22 2006-04-07 서홍석 4-[(알킬설판일)메틸]-1,2-벤젠디올 유도체, 이의제조방법 및 이를 포함하는 항산화제
US7148226B2 (en) * 2003-02-21 2006-12-12 Agouron Pharmaceuticals, Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
AU2005273619B2 (en) * 2004-08-18 2009-05-28 Pfizer Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3868367A (en) * 1974-04-11 1975-02-25 Warner Lambert Co 4-Hydroxy-3-(5-isoxazolylcarbamoyl)-2H-1,2-benzothiazine 1,1-dioxides
FI832754A (fi) * 1982-08-09 1984-02-10 Ppg Industries Inc Foerfarande foer framstaellning av 3-amino-5-(substituerad)isoxazol

Also Published As

Publication number Publication date
ES530855A0 (es) 1985-07-01
ES538032A0 (es) 1985-11-01
ES8601936A1 (es) 1985-11-01
DE3468876D1 (en) 1988-02-25
US4489077A (en) 1984-12-18
AU2514984A (en) 1984-09-27
GR81482B (es) 1984-12-11
AU562834B2 (en) 1987-06-18
DK118884D0 (da) 1984-02-28
EP0123418B1 (en) 1988-01-20
CA1229599A (en) 1987-11-24
EP0123418A1 (en) 1984-10-31
DK118884A (da) 1984-09-24

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