ES8407032A1 - Un procedimiento para preparar acido 2-(4-(2-tiazoliloxi)fenil) propionico. - Google Patents

Un procedimiento para preparar acido 2-(4-(2-tiazoliloxi)fenil) propionico.

Info

Publication number
ES8407032A1
ES8407032A1 ES519778A ES519778A ES8407032A1 ES 8407032 A1 ES8407032 A1 ES 8407032A1 ES 519778 A ES519778 A ES 519778A ES 519778 A ES519778 A ES 519778A ES 8407032 A1 ES8407032 A1 ES 8407032A1
Authority
ES
Spain
Prior art keywords
thiazolyloxy
phenyl
production
propionic acid
improved process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519778A
Other languages
English (en)
Other versions
ES519778A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES8407032A1 publication Critical patent/ES8407032A1/es
Publication of ES519778A0 publication Critical patent/ES519778A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ACIDO 2-4-(2-TIAZOLILOXI) FENIL-PROPIONICO.COMPRENDE: HACER REACCIONAR UN COMPUESTO DE FORMULA (I) CON 1 A 3 EQUIVALENTES EN MOLES DE BROMURO DE METILO EN DIMETILFORMAMIDA A UNA TEMPERATURA DE C5 A 5JC, EN PRESENCIA DE 1 A 3 EQUIVALENTES EN MOLES DE HIDROXIDO DE POTASIO EN POLVO; E HIDROLIZAR UN COMPUESTO DE FORMULA (II) CON 2 A 6 EQUIVALENTES EN MOLES DE HIDROXIDO DE SODIO A UNA TEMPERATURA DE 0 A 70JC EN METANOL, ETANOL O ISOPROPANOL, PARA OBTENER ACIDO 2-4-(2-TIAZOLILOXI)FENIL-PROPIONICO, DONDE R ES ISOPROPILO, SEC-BUTILO O BENZHIDRILO.TIENE APLICACION FARMACOÑOGICA COMO ANTI-INFLAMATORIOY ANALGESICO.
ES519778A 1982-02-26 1983-02-14 Un procedimiento para preparar acido 2-(4-(2-tiazoliloxi)fenil) propionico. Granted ES519778A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57031428A JPS58148870A (ja) 1982-02-26 1982-02-26 ２−〔４−（２−チアゾリルオキシ）フエニル〕プロピオン酸の工業的製造法

Publications (2)

Publication Number Publication Date
ES8407032A1 true ES8407032A1 (es) 1984-08-16
ES519778A0 ES519778A0 (es) 1984-08-16

Family

ID=12330965

Family Applications (1)

Application Number Title Priority Date Filing Date
ES519778A Granted ES519778A0 (es) 1982-02-26 1983-02-14 Un procedimiento para preparar acido 2-(4-(2-tiazoliloxi)fenil) propionico.

Country Status (10)

Country Link
EP (1) EP0088008B1 (es)
JP (1) JPS58148870A (es)
KR (1) KR840003622A (es)
AT (1) ATE25380T1 (es)
CA (1) CA1188699A (es)
DK (1) DK95283A (es)
ES (1) ES519778A0 (es)
HU (1) HU187863B (es)
PH (1) PH18619A (es)
ZA (1) ZA83639B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
KR970042541A (ko) * 1995-12-11 1997-07-24 김준웅 알킬 페닐프로피오네트 유도체-14c의 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1051906A (en) * 1973-10-24 1979-04-03 Shionogi And Co. Thiazole derivatives and production thereof

Also Published As

Publication number Publication date
JPS58148870A (ja) 1983-09-05
ZA83639B (en) 1983-10-26
EP0088008B1 (en) 1987-02-04
ES519778A0 (es) 1984-08-16
KR840003622A (ko) 1984-09-15
HU187863B (en) 1986-02-28
PH18619A (en) 1985-08-21
EP0088008A1 (en) 1983-09-07
ATE25380T1 (de) 1987-02-15
DK95283A (da) 1983-08-27
DK95283D0 (da) 1983-02-25
CA1188699A (en) 1985-06-11

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