ES8405390A1 - Un procedimiento para preparar compuestos de quinolona. - Google Patents

Un procedimiento para preparar compuestos de quinolona.

Info

Publication number
ES8405390A1
ES8405390A1 ES521153A ES521153A ES8405390A1 ES 8405390 A1 ES8405390 A1 ES 8405390A1 ES 521153 A ES521153 A ES 521153A ES 521153 A ES521153 A ES 521153A ES 8405390 A1 ES8405390 A1 ES 8405390A1
Authority
ES
Spain
Prior art keywords
amino
dihydro
oxo
fluoro
antibacterial agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521153A
Other languages
English (en)
Other versions
ES521153A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ES8405390A1 publication Critical patent/ES8405390A1/es
Publication of ES521153A0 publication Critical patent/ES521153A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE QUINOLONA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA ZFNH PARA DAR COMPUESTOS DE QUINOLONA DE FORMULA (I), DONDE R ES AMINO, ALQUILO-INFERIOR-AMINO, Z-PROPENIL AMINO, N-FORMIL-ALQUILO-INFERIOR-AMINO O DI-ALQUILO-INFERIOR-AMINO; R ES HIDROGENO O ALQUILO INFERIOR Y ZFN ES UN GRUPO HETEROCICLICO; Y RO ES AMINO, ALQUILO-INFERIOR-AMINO, Z-PROPENILAMINO O DI-ALQUILO-INFERIOR-AMINO.TIENE APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES COMO AGENTES ANTIBACTERIANOS.
ES521153A 1982-03-31 1983-03-30 Un procedimiento para preparar compuestos de quinolona. Granted ES521153A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36387682A 1982-03-31 1982-03-31
US06/466,095 US4499091A (en) 1982-03-31 1983-02-14 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents

Publications (2)

Publication Number Publication Date
ES8405390A1 true ES8405390A1 (es) 1984-06-01
ES521153A0 ES521153A0 (es) 1984-06-01

Family

ID=27002249

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521153A Granted ES521153A0 (es) 1982-03-31 1983-03-30 Un procedimiento para preparar compuestos de quinolona.

Country Status (14)

Country Link
US (1) US4499091A (es)
KR (1) KR880002353B1 (es)
AU (1) AU557534B2 (es)
CA (1) CA1198425A (es)
DK (1) DK162638C (es)
ES (1) ES521153A0 (es)
FI (1) FI77855C (es)
GR (1) GR77906B (es)
IE (1) IE54898B1 (es)
IL (1) IL68236A (es)
NO (1) NO158060C (es)
NZ (1) NZ203621A (es)
PH (1) PH18392A (es)
PT (1) PT76456B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3409922A1 (de) * 1984-03-17 1985-09-26 Bayer Ag, 5090 Leverkusen 1,7-diamino-1,4-dihydro-4-oxo-3-(aza)chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung bakterieller erkrankungen
FR2574404B1 (fr) * 1984-12-12 1987-04-24 Provesan Sa Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
IN166416B (es) * 1985-09-18 1990-05-05 Pfizer
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3606698A1 (de) * 1986-03-01 1987-09-03 Bayer Ag 7-(1-pyrrolidinyl)-chinoloncarbonsaeure -derivate
US5153204A (en) * 1986-03-01 1992-10-06 Bayer Aktiengesellschaft 7-(1-Pyrrolidinyl)-quinolonecarboxylic acid derivatives
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
IL83049A (en) * 1986-07-04 1991-12-12 Chemie Linz Ag 4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
EP0259804B1 (de) * 1986-09-12 1993-11-18 F. Hoffmann-La Roche Ag Pyrido [3,2,1-ij]-1,3,4-benzoxadiazinderivate, Verfahren zu deren Herstellung, entsprechende pharmazeutische Präparate und im Verfahren verwendbare Zwischenprodukte
US4929613A (en) * 1987-08-26 1990-05-29 Warner-Lambert Company Antibacterial agents
US4868305A (en) * 1988-02-16 1989-09-19 Sterling Drug Inc. Improvement in the preparation of intermediates for quinoline antibacterial agents
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
JP2003527308A (ja) 1998-12-04 2003-09-16 インフラックス，インコーポレイテッド 多剤輸送体の阻害剤
US6262072B1 (en) 1999-10-12 2001-07-17 Yung Shin Pharmaceutical Industrial Co. Ltd. Orally administered antimicrobial pharmaceutical formulations of ciprofloxacin
US6957105B2 (en) * 2002-03-26 2005-10-18 Cardiac Pacemakers, Inc. Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals
US20070196398A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone fatty acid salt compositions
US20070197548A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
CA1175836A (en) * 1977-09-20 1984-10-09 Marcel Pesson Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten

Also Published As

Publication number Publication date
KR840004102A (ko) 1984-10-06
NO158060C (no) 1988-07-06
IE54898B1 (en) 1990-03-14
PT76456B (en) 1985-12-10
AU1272283A (en) 1983-10-06
KR880002353B1 (ko) 1988-10-29
DK145983D0 (da) 1983-03-30
AU557534B2 (en) 1986-12-24
FI77855C (fi) 1989-05-10
CA1198425A (en) 1985-12-24
IE830608L (en) 1983-09-30
GR77906B (es) 1984-09-25
IL68236A (en) 1986-09-30
PH18392A (en) 1985-06-21
DK162638B (da) 1991-11-25
FI77855B (fi) 1989-01-31
FI831102L (fi) 1983-10-01
US4499091A (en) 1985-02-12
PT76456A (en) 1983-04-01
NO158060B (no) 1988-03-28
DK162638C (da) 1992-04-21
NZ203621A (en) 1986-01-24
IL68236A0 (en) 1983-06-15
DK145983A (da) 1983-10-01
FI831102A0 (fi) 1983-03-30
ES521153A0 (es) 1984-06-01
NO831056L (no) 1983-10-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203