ES8404340A1 - Procedimientos para preparar derivados piridazinona. - Google Patents

Procedimientos para preparar derivados piridazinona.

Info

Publication number
ES8404340A1
ES8404340A1 ES517333A ES517333A ES8404340A1 ES 8404340 A1 ES8404340 A1 ES 8404340A1 ES 517333 A ES517333 A ES 517333A ES 517333 A ES517333 A ES 517333A ES 8404340 A1 ES8404340 A1 ES 8404340A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
compositions containing
oxadiazine
thiadiazine
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517333A
Other languages
English (en)
Other versions
ES517333A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES517333A0 publication Critical patent/ES517333A0/es
Publication of ES8404340A1 publication Critical patent/ES8404340A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
    • C07D273/04—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRIDAZINONA Y DE SUS SALES, DE FORMULA (I), EN LA QUE X, Y, R Y R PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN ACIDO DE FORMULA (II) O UN DERIVADO ACTIVADO DEL MISMO, CON UN ALCOHOL, DE FORMULA HOR O UNO DE SUS DERIVADOS ACTIVADOS, EN LAS QUE R Y R SON CARBOXI Y R, X E Y PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO SIGUIENDO METODOS CONVENCIONALES.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES CARDIOTONICAS Y/O ANTIHIPERTENSIVAS.
ES517333A 1981-11-12 1982-11-12 Procedimientos para preparar derivados piridazinona. Expired ES8404340A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8134176 1981-11-12

Publications (2)

Publication Number Publication Date
ES517333A0 ES517333A0 (es) 1984-04-16
ES8404340A1 true ES8404340A1 (es) 1984-04-16

Family

ID=10525837

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517333A Expired ES8404340A1 (es) 1981-11-12 1982-11-12 Procedimientos para preparar derivados piridazinona.

Country Status (12)

Country Link
US (1) US4493835A (es)
EP (1) EP0086301A1 (es)
JP (1) JPS58131973A (es)
AU (1) AU9000682A (es)
DK (1) DK487082A (es)
ES (1) ES8404340A1 (es)
FI (1) FI823895L (es)
GR (1) GR77782B (es)
IL (1) IL67098A0 (es)
NO (1) NO823765L (es)
PT (1) PT75828A (es)
ZA (1) ZA827641B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172252D1 (en) * 1980-11-14 1985-10-17 Ici Plc Heterocyclic compounds
US4657906A (en) * 1982-06-05 1987-04-14 Smith Kline & French Laboratories Ltd. Heterocyclic compounds having inotropic activity
GB8310435D0 (en) * 1983-04-18 1983-05-25 Fujisawa Pharmaceutical Co Triazine derivatives
GB8328907D0 (en) * 1983-10-28 1983-11-30 Smith Kline French Lab Chemical compounds
GB8332313D0 (en) * 1983-12-02 1984-01-11 Smith Kline French Lab Chemical compounds
US4508718A (en) * 1984-01-16 1985-04-02 Warner-Lambert Company Cardiotonic and antihypertensive oxadiazinone compounds
US4898862A (en) * 1986-03-20 1990-02-06 Sankyo Company Limited 1,2,4-triazinone derivatives, their preparation and use
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
EP3661917B1 (en) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون
TWI750573B (zh) * 2019-02-01 2021-12-21 德商拜耳廠股份有限公司 1,2,4-三-3(2h)-酮化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3377345A (en) * 1966-09-23 1968-04-09 Dow Chemical Co Substituted 3, 4, 5, 6-tetrahydro-2h-1, 3, 4-oxadiazin-2-one compounds and method ofpreparation thereof
FR8169M (es) * 1967-05-17 1970-08-31
US3946010A (en) * 1975-04-09 1976-03-23 E. R. Squibb & Sons, Inc. 3-Phenyl-2,5-dihydro-as-triazin-6 (1H)-ones
US4097671A (en) * 1975-08-28 1978-06-27 General Electric Company Dihydrooxadiazinones and method for making
US4097425A (en) * 1975-08-28 1978-06-27 General Electric Company Thermoplastic formable blends, a foaming method and products made thereby
US4105848A (en) * 1976-12-27 1978-08-08 General Electric Company Process for the production of dihydrooxadiazinone compounds
DE3172252D1 (en) * 1980-11-14 1985-10-17 Ici Plc Heterocyclic compounds

Also Published As

Publication number Publication date
ES517333A0 (es) 1984-04-16
PT75828A (en) 1982-12-01
AU9000682A (en) 1983-05-19
EP0086301A1 (en) 1983-08-24
IL67098A0 (en) 1983-02-23
US4493835A (en) 1985-01-15
GR77782B (es) 1984-09-25
ZA827641B (en) 1983-09-28
FI823895A0 (fi) 1982-11-12
DK487082A (da) 1983-05-13
JPS58131973A (ja) 1983-08-06
FI823895L (fi) 1983-05-13
NO823765L (no) 1983-05-13

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