ES8403920A1 - Procedimiento para la obtencion de b-lactamantibioticos. - Google Patents
Procedimiento para la obtencion de b-lactamantibioticos.Info
- Publication number
- ES8403920A1 ES8403920A1 ES523797A ES523797A ES8403920A1 ES 8403920 A1 ES8403920 A1 ES 8403920A1 ES 523797 A ES523797 A ES 523797A ES 523797 A ES523797 A ES 523797A ES 8403920 A1 ES8403920 A1 ES 8403920A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- ring
- beta
- preparation
- preparations containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title 2
- 239000003782 beta lactam antibiotic agent Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000002132 β-lactam antibiotic Substances 0.000 title 1
- 229940124586 β-lactam antibiotics Drugs 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000003367 polycyclic group Chemical group 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE BLACTAMANTIBIOTICOS Y DE SUS SALES NO TOXICAS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE Z ES HIDROGENO O ALCOXI INFERIOR; Y, Z Y A PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 1 O 2.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN LOS MISMO SIGNIFICADOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, TAL COMO CLORURO DE METILENO, A LA TEMPERATURA AMBIENTE. EL PRODUCTO OBTENIDO SE SEPARA Y PURIFICA SIGUIENDO METODOS CONVENCIONALES.ESTOSCOMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBACTERIALES, PARA PIENSOS DE ANIMALES Y COMO ANTIOXIDANTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823224866 DE3224866A1 (de) | 1982-07-02 | 1982-07-02 | Ss-lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403920A1 true ES8403920A1 (es) | 1984-04-01 |
| ES523797A0 ES523797A0 (es) | 1984-04-01 |
Family
ID=6167504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES523797A Granted ES523797A0 (es) | 1982-07-02 | 1983-07-01 | Procedimiento para la obtencion de b-lactamantibioticos. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4735938A (es) |
| EP (1) | EP0098433B1 (es) |
| JP (1) | JPS5931777A (es) |
| AT (1) | ATE31191T1 (es) |
| CA (1) | CA1222507A (es) |
| DE (2) | DE3224866A1 (es) |
| DK (1) | DK306983A (es) |
| ES (1) | ES523797A0 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3224866A1 (de) * | 1982-07-02 | 1984-01-05 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
| AU575854B2 (en) * | 1983-10-04 | 1988-08-11 | Shionogi & Co., Ltd. | 7beta-(carboxyalkenamido) cephalosporins |
| DE3419012A1 (de) * | 1984-05-22 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien |
| DE3807232A1 (de) * | 1988-03-05 | 1989-09-14 | Bayer Ag | Substituierte acrylsaeureester |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3622569A (en) * | 1969-08-05 | 1971-11-23 | R & L Molecular Research Ltd | 6-(2-aryl-3-azido-and-3-amino-methyl-isocrotonamido)penicillanic acids |
| GB1497039A (en) * | 1973-12-05 | 1978-01-05 | Glaxo Lab Ltd | Penicillins and cephalosporins |
| GB1565941A (en) * | 1977-02-08 | 1980-04-23 | Toyama Chemical Co Ltd | Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids |
| US4405617A (en) * | 1980-02-11 | 1983-09-20 | Fujisawa Pharmaceutical Co., Ltd. | 3-(Propynyltetrazol)thiomethyl-3-cephems |
| GB2076801A (en) * | 1980-04-14 | 1981-12-09 | Erba Farmitalia | alpha , beta -Disubstituted Acrylamido Cephalosporins |
| DE3037997A1 (de) * | 1980-10-08 | 1982-05-13 | Bayer Ag | (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
| DE3224866A1 (de) * | 1982-07-02 | 1984-01-05 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
-
1982
- 1982-07-02 DE DE19823224866 patent/DE3224866A1/de not_active Withdrawn
-
1983
- 1983-06-18 DE DE8383105959T patent/DE3374783D1/de not_active Expired
- 1983-06-18 AT AT83105959T patent/ATE31191T1/de active
- 1983-06-18 EP EP83105959A patent/EP0098433B1/de not_active Expired
- 1983-06-30 CA CA000431600A patent/CA1222507A/en not_active Expired
- 1983-07-01 ES ES523797A patent/ES523797A0/es active Granted
- 1983-07-01 JP JP58118381A patent/JPS5931777A/ja active Pending
- 1983-07-01 DK DK306983A patent/DK306983A/da not_active Application Discontinuation
-
1986
- 1986-07-10 US US06/884,328 patent/US4735938A/en not_active Expired - Fee Related
-
1987
- 1987-09-30 US US07/103,240 patent/US4808724A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5931777A (ja) | 1984-02-20 |
| DE3374783D1 (en) | 1988-01-14 |
| DK306983D0 (da) | 1983-07-01 |
| DE3224866A1 (de) | 1984-01-05 |
| EP0098433A2 (de) | 1984-01-18 |
| EP0098433B1 (de) | 1987-12-02 |
| CA1222507A (en) | 1987-06-02 |
| DK306983A (da) | 1984-01-03 |
| EP0098433A3 (en) | 1985-01-09 |
| US4808724A (en) | 1989-02-28 |
| US4735938A (en) | 1988-04-05 |
| ES523797A0 (es) | 1984-04-01 |
| ATE31191T1 (de) | 1987-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL63959A (en) | 6-and 7-(1-(2-aminothiazol-4-yl)-ethencarbamido)-penicillins and cephalosporins,their preparation and pharmaceutical compositions containing them | |
| GB1456144A (en) | Ureido-aryl cephalosporin compounds | |
| ES463737A1 (es) | Metodo para producir cefalosporinas y similares | |
| EP0214600A3 (en) | Cephalosporin derivatives | |
| ES8403920A1 (es) | Procedimiento para la obtencion de b-lactamantibioticos. | |
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| AU6366286A (en) | Tetrahydro-beta-carbolines, process for their production and their use as drugs | |
| DE3171431D1 (en) | Derivatives of 7-beta-(ketoximinoacylamido)-ceph-3-em-4-carboxylic acids, process for their preparation and their pharmaceutical compositions containing them | |
| ES8300772A1 (es) | Un procedimiento para la preparacion de derivados de penici-lina. | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991108 |