ES8402287A1 - Procedimiento de obtencion de nuevas carboxamidoguanidinas. - Google Patents

Procedimiento de obtencion de nuevas carboxamidoguanidinas.

Info

Publication number
ES8402287A1
ES8402287A1 ES521720A ES521720A ES8402287A1 ES 8402287 A1 ES8402287 A1 ES 8402287A1 ES 521720 A ES521720 A ES 521720A ES 521720 A ES521720 A ES 521720A ES 8402287 A1 ES8402287 A1 ES 8402287A1
Authority
ES
Spain
Prior art keywords
carboxamidoguanidins
pharmaceutical compositions
obtaining
new
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521720A
Other languages
English (en)
Other versions
ES521720A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8402287A1 publication Critical patent/ES8402287A1/es
Publication of ES521720A0 publication Critical patent/ES521720A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE CARBOXAMIDOGUANIDINAS, DE FORMULA GENERAL (I), EN LA QUE R1 Y R2, DISTINTAMENTE EL UNO DEL OTRO, REPRESENTAN HIDROGENO, UN HALOGENO O UN RADICAL ALCOXI INFERIOR; R3 REPRESENTA UN RADICAL ALCOHILO INFERIOR O UN RADICAL ALCENILO INFERIOR; R4 REPRESENTA HIDROGENO, UN RADICAL ALCOHILO INFERIOR O UN RADICAL ARALCOHILO INFERIOR; A REPRESENTA UN ENLACE SENCILLO; B REPRESENTA -CHOH O -CO-; N REPRESENTA 0 O 1; Y N ELEVADO, REPRESENTA 0 O 1. CONSISTE ENSOMETER UNA CIANOGUANIDINA, DE FORMULA GENERAL (II), EN LA QUE R1, R2, R3, R4, A, B, N Y N ELEVADO, TIENEN EL SIGNIFICADO YA MENCIONADO, A LA ACCION DE UN AGENTE DE HIDROLISIS ACIDO, PARA OBTENER LA CARBOXAMIDOGUANIDINA, DE FORMULA GENERAL (I). DE APLICACION EN FARMACIA POR SUS PROPIEDADES ANTI-HIPERTENSIVAS ASOCIADAS CON UNA ACCION DEBILMENTE SEDATIVA SOBRE EL SISTEMA NERVIOSO CENTRAL. *FORMULA*.
ES521720A 1982-04-21 1983-04-21 Procedimiento de obtencion de nuevas carboxamidoguanidinas. Granted ES521720A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206832A FR2525600A1 (fr) 1982-04-21 1982-04-21 Nouvelles carboxamidoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant

Publications (2)

Publication Number Publication Date
ES8402287A1 true ES8402287A1 (es) 1984-02-01
ES521720A0 ES521720A0 (es) 1984-02-01

Family

ID=9273210

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521720A Granted ES521720A0 (es) 1982-04-21 1983-04-21 Procedimiento de obtencion de nuevas carboxamidoguanidinas.

Country Status (9)

Country Link
EP (1) EP0106860B1 (es)
JP (1) JPS59500672A (es)
CA (1) CA1207768A (es)
DE (1) DE3375394D1 (es)
ES (1) ES521720A0 (es)
FI (1) FI834704A0 (es)
FR (1) FR2525600A1 (es)
OA (1) OA08257A (es)
WO (1) WO1983003829A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008106633A1 (en) * 2007-03-01 2008-09-04 Xenon Pharmaceuticals Inc. Methods of using benzodioxine compounds in treating sodium channel-mediated diseases or conditions
TWI457122B (zh) * 2007-07-20 2014-10-21 Orion Corp 作為用於治療周邊和中央神經系統疾病之alpha2C拮抗劑的2,3－二氫苯並[1,4]戴奧辛－2－基甲基衍生物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71865B (es) * 1978-03-20 1983-07-07 Ciba Geigy

Also Published As

Publication number Publication date
EP0106860A1 (fr) 1984-05-02
EP0106860B1 (fr) 1988-01-20
FR2525600B3 (es) 1985-01-25
FR2525600A1 (fr) 1983-10-28
DE3375394D1 (en) 1988-02-25
WO1983003829A1 (fr) 1983-11-10
FI834704A (fi) 1983-12-21
OA08257A (fr) 1987-10-30
ES521720A0 (es) 1984-02-01
CA1207768A (fr) 1986-07-15
JPS59500672A (ja) 1984-04-19
FI834704A0 (fi) 1983-12-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301