ES8307832A1 - "un procedimiento para preparar acido 2',4'-difluoro-4-fosfonoxi-(1,1'-difenil)-3-carboxi". - Google Patents

"un procedimiento para preparar acido 2',4'-difluoro-4-fosfonoxi-(1,1'-difenil)-3-carboxi".

Info

Publication number
ES8307832A1
ES8307832A1 ES513246A ES513246A ES8307832A1 ES 8307832 A1 ES8307832 A1 ES 8307832A1 ES 513246 A ES513246 A ES 513246A ES 513246 A ES513246 A ES 513246A ES 8307832 A1 ES8307832 A1 ES 8307832A1
Authority
ES
Spain
Prior art keywords
antipyretic
analgesic
inflammatory
preparation
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513246A
Other languages
English (en)
Other versions
ES513246A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Malesci Instituto Farmacobiologico SpA
Original Assignee
Malesci Instituto Farmacobiologico SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Malesci Instituto Farmacobiologico SpA filed Critical Malesci Instituto Farmacobiologico SpA
Publication of ES8307832A1 publication Critical patent/ES8307832A1/es
Publication of ES513246A0 publication Critical patent/ES513246A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ACIDO 2 ,4 -DIFLUORO-4-FOSFONOXI-(1,1 -DIFENIL)-3-CARBOXI Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN LA REACCION DEL ACIDO 2 ,4 -DIFLUORO-4-HIDROXI-(1,1 -DIFENIL)-3-CARBOXI CON PENTACLORURO DE FOSFORO A UNA TEMPERATURA ENTRE 75 C Y 80 C; SEGUIDA DEL ENFRIAMIENTO DE LA MASA A UNOS 5 C, DISOLUCION EN UNA MEZCLA DE ACETONA Y BENCENO; Y FINALMENTE, TRATAMIENTO CON AGUA PARA HIDROLIZAR A UNA TEMPERATURA ENTRE 25 C Y 30 C. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANTIINFLAMATORIO, ANALGESICO Y ANTIPIRETICO.
ES513246A 1981-06-19 1982-06-18 "un procedimiento para preparar acido 2',4'-difluoro-4-fosfonoxi-(1,1'-difenil)-3-carboxi". Granted ES513246A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48719/81A IT1171318B (it) 1981-06-19 1981-06-19 Composto idrosolubile ad attivita' antinfiammatoria analgesica antipiretica e relativo procedimento di preparazione

Publications (2)

Publication Number Publication Date
ES8307832A1 true ES8307832A1 (es) 1983-07-01
ES513246A0 ES513246A0 (es) 1983-07-01

Family

ID=11268237

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513246A Granted ES513246A0 (es) 1981-06-19 1982-06-18 "un procedimiento para preparar acido 2',4'-difluoro-4-fosfonoxi-(1,1'-difenil)-3-carboxi".

Country Status (9)

Country Link
JP (1) JPS5843986A (es)
BE (1) BE893563A (es)
CA (1) CA1189527A (es)
DE (1) DE3223486A1 (es)
ES (1) ES513246A0 (es)
FR (1) FR2508044B1 (es)
GB (1) GB2101135B (es)
IT (1) IT1171318B (es)
NL (1) NL8202473A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270996B (it) * 1994-07-22 1997-05-26 Wilton Licensing Ag Derivati fosforilati di composti aventi attivita' antiinfiammatoria o analgesica e procedimento per la loro preparazione

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714226A (en) * 1970-06-09 1973-01-30 Merck & Co Inc Phenyl benzoic acid compounds
DE2641526A1 (de) * 1976-07-01 1978-01-12 Uriach & Cia Sa J 2-phosphonoxybenzoesaeure, deren salze, verfahren zu deren herstellung und pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
DE3223486A1 (de) 1983-02-17
GB2101135A (en) 1983-01-12
GB2101135B (en) 1984-10-24
CA1189527A (en) 1985-06-25
BE893563A (fr) 1982-10-18
ES513246A0 (es) 1983-07-01
IT1171318B (it) 1987-06-10
NL8202473A (nl) 1983-01-17
IT8148719A0 (it) 1981-06-19
FR2508044B1 (fr) 1985-07-26
JPS5843986A (ja) 1983-03-14
FR2508044A1 (fr) 1982-12-24

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