ES8307246A1 - "procedimiento de preparacion de nuevos compuestos de lactama". - Google Patents

"procedimiento de preparacion de nuevos compuestos de lactama".

Info

Publication number
ES8307246A1
ES8307246A1 ES516597A ES516597A ES8307246A1 ES 8307246 A1 ES8307246 A1 ES 8307246A1 ES 516597 A ES516597 A ES 516597A ES 516597 A ES516597 A ES 516597A ES 8307246 A1 ES8307246 A1 ES 8307246A1
Authority
ES
Spain
Prior art keywords
compounds
preparation
formula
pharmaceutical preparations
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516597A
Other languages
English (en)
Other versions
ES516597A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of ES8307246A1 publication Critical patent/ES8307246A1/es
Publication of ES516597A0 publication Critical patent/ES516597A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE LACTAMA, DE FORMULA (I), EN LA QUE R ES ALQUILO DE 1 A 4 ATOMOS DE CARBONO. CONSISTE EN LA REACCION DE CICLIZACION DE UN DERIVADO DEL ACIDO VALERICO, DE FORMULA (II), EN LA QUE X TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). Y ES CLORO, BROMO, YODO, HIDROXILO O AMINO Y Z ES AMINO O HIDROXILO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE BASES O ACIDO, DEPENDIENDO DE LAS CARACTERISTICAS DEL SUSTITUYENTE Y, A LA TEMPERATURA AMBIENTE O CON CALENTAMIENTO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO CALMANTES DEL SISTEMA NERVIOSO CENTRAL.
ES516597A 1980-12-23 1982-10-16 "procedimiento de preparacion de nuevos compuestos de lactama". Granted ES516597A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803048663 DE3048663A1 (de) 1980-12-23 1980-12-23 Neue lactamverbindungen, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel

Publications (2)

Publication Number Publication Date
ES8307246A1 true ES8307246A1 (es) 1983-06-16
ES516597A0 ES516597A0 (es) 1983-06-16

Family

ID=6120078

Family Applications (2)

Application Number Title Priority Date Filing Date
ES506792A Expired ES8302702A1 (es) 1980-12-23 1981-11-02 Procedimiento para la produccion de nuevos compuestos de lactama.
ES516597A Granted ES516597A0 (es) 1980-12-23 1982-10-16 "procedimiento de preparacion de nuevos compuestos de lactama".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES506792A Expired ES8302702A1 (es) 1980-12-23 1981-11-02 Procedimiento para la produccion de nuevos compuestos de lactama.

Country Status (14)

Country Link
US (1) US4399145A (es)
EP (1) EP0054672A1 (es)
JP (1) JPS57123178A (es)
KR (1) KR830007639A (es)
AU (1) AU7730281A (es)
DE (1) DE3048663A1 (es)
DK (1) DK567181A (es)
ES (2) ES8302702A1 (es)
FI (1) FI814067L (es)
GR (1) GR75377B (es)
IL (1) IL64043A0 (es)
NO (1) NO813693L (es)
PT (1) PT73949B (es)
YU (1) YU306781A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
DE4422237A1 (de) * 1994-06-24 1996-01-04 Gruenenthal Gmbh Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe
WO2001082386A1 (fr) 2000-04-24 2001-11-01 Rohm Co., Ltd. Dispositif semi-conducteur electroluminescent a emission laterale et son procede de production
US6680331B2 (en) * 2001-07-16 2004-01-20 Board Of Regents, The University Of Texas System Lactam and thiolactam derivatives as anesthetic and conscious sedation agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205791A1 (es) * 1972-03-03 1976-06-07 Gruenenthal Chemie Procedimiento de preparacion de sulfobenzo lactamas

Also Published As

Publication number Publication date
DK567181A (da) 1982-06-24
EP0054672A1 (de) 1982-06-30
ES506792A0 (es) 1983-02-01
NO813693L (no) 1982-06-24
DE3048663A1 (de) 1982-07-22
US4399145A (en) 1983-08-16
YU306781A (en) 1984-04-30
KR830007639A (ko) 1983-11-04
AU7730281A (en) 1982-07-01
IL64043A0 (en) 1982-01-31
ES8302702A1 (es) 1983-02-01
PT73949B (de) 1983-04-18
JPS57123178A (en) 1982-07-31
ES516597A0 (es) 1983-06-16
FI814067L (fi) 1982-06-24
GR75377B (es) 1984-07-13
PT73949A (de) 1981-12-01

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