ES8305689A1 - Derivatives of 3-amino-1,2-propane diol. - Google Patents

Derivatives of 3-amino-1,2-propane diol.

Info

Publication number
ES8305689A1
ES8305689A1 ES514365A ES514365A ES8305689A1 ES 8305689 A1 ES8305689 A1 ES 8305689A1 ES 514365 A ES514365 A ES 514365A ES 514365 A ES514365 A ES 514365A ES 8305689 A1 ES8305689 A1 ES 8305689A1
Authority
ES
Spain
Prior art keywords
derivatives
amino
formula
image
propane diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514365A
Other languages
Spanish (es)
Other versions
ES514365A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8305689A1 publication Critical patent/ES8305689A1/en
Publication of ES514365A0 publication Critical patent/ES514365A0/en
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivatives of 3-amino-1,2-propanediol of the formula < IMAGE > in which R11 denotes polyhydroxy-lower alkyl, cycloalkyl-lower alkoxy-lower alkyl, lower alkylsulphonylamino bonded in the 4-position or 1-lower alkylcarbamoyl-2-vinyl bonded in the 4-position, and alk denotes radicals of the formula -CH2-CH2- or < IMAGE > and salts of such compounds, process for their preparation, pharmaceuticals which contain the novel compounds, and their use as blockers of adrenergic ss-receptors for the treatment of angina pectoris and cardiac arrhythmias, and also as hypotensive agents.
ES514365A 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL. Granted ES514365A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH611880 1980-08-13

Publications (2)

Publication Number Publication Date
ES8305689A1 true ES8305689A1 (en) 1983-04-16
ES514365A0 ES514365A0 (en) 1983-04-16

Family

ID=4304561

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504682A Expired ES8301462A1 (en) 1980-08-13 1981-08-11 Derivatives of 3-amino-1,2-propane diol.
ES514367A Granted ES514367A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, 2-PROPANDIOL
ES514366A Expired ES8305690A1 (en) 1980-08-13 1982-07-26 Derivatives of 3-amino-1,2-propane diol.
ES514371A Granted ES514371A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, S-PROPANDIOL
ES514370A Granted ES514370A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1 2-PROPANDIOL
ES514365A Granted ES514365A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL.
ES514369A Granted ES514369A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, 2-PROPANDIOL
ES514368A Expired ES8305692A1 (en) 1980-08-13 1982-07-26 Derivatives of 3-amino-1,2-propane diol.

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES504682A Expired ES8301462A1 (en) 1980-08-13 1981-08-11 Derivatives of 3-amino-1,2-propane diol.
ES514367A Granted ES514367A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, 2-PROPANDIOL
ES514366A Expired ES8305690A1 (en) 1980-08-13 1982-07-26 Derivatives of 3-amino-1,2-propane diol.
ES514371A Granted ES514371A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, S-PROPANDIOL
ES514370A Granted ES514370A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1 2-PROPANDIOL

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES514369A Granted ES514369A0 (en) 1980-08-13 1982-07-26 PROCEDURE FOR OBTAINING DERIVATIVES OF 3-AMINO-1, 2-PROPANDIOL
ES514368A Expired ES8305692A1 (en) 1980-08-13 1982-07-26 Derivatives of 3-amino-1,2-propane diol.

Country Status (17)

Country Link
EP (1) EP0045964A1 (en)
JP (1) JPS5759842A (en)
KR (1) KR840002266B1 (en)
AR (6) AR231273A1 (en)
AU (1) AU543647B2 (en)
CA (1) CA1192221A (en)
DD (3) DD202532A5 (en)
DK (1) DK358381A (en)
ES (8) ES8301462A1 (en)
FI (1) FI812465L (en)
GR (1) GR74992B (en)
HU (1) HU186342B (en)
IL (1) IL63539A (en)
NO (1) NO812736L (en)
NZ (1) NZ198020A (en)
PT (1) PT73511B (en)
ZA (1) ZA815554B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58417B1 (en) * 1984-04-27 1993-09-22 Ici Plc Chemical derivatives
GB201101959D0 (en) * 2011-02-04 2011-03-23 Univ Nottingham Novel ether linked compoundsand improved treatments for cardiac and cardiovascular disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1398738A (en) * 1972-12-05 1975-06-25 Pfizer Ltd Propanolamine derivatives
DD144050A5 (en) * 1978-06-05 1980-09-24 Ciba Geigy Ag PROCESS FOR THE PREPARATION OF N-ALKYLATED AMINO ALCOHOLS
DD150456A5 (en) * 1979-03-01 1981-09-02 Ciba Geigy Ag PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL

Also Published As

Publication number Publication date
ES514366A0 (en) 1983-05-01
AU7402081A (en) 1982-02-18
ZA815554B (en) 1982-08-25
AR231631A1 (en) 1985-01-31
ES8305691A1 (en) 1983-04-16
FI812465L (en) 1982-02-14
CA1192221A (en) 1985-08-20
ES8305690A1 (en) 1983-05-01
PT73511B (en) 1983-07-06
ES514367A0 (en) 1983-04-16
NZ198020A (en) 1985-04-30
DD202532A5 (en) 1983-09-21
AR231275A1 (en) 1984-10-31
IL63539A (en) 1984-11-30
ES8305694A1 (en) 1983-05-01
ES504682A0 (en) 1982-12-01
ES514368A0 (en) 1983-05-01
ES8305693A1 (en) 1983-05-01
KR830006173A (en) 1983-09-17
ES8301462A1 (en) 1982-12-01
ES514365A0 (en) 1983-04-16
ES8305692A1 (en) 1983-05-01
DK358381A (en) 1982-02-14
HU186342B (en) 1985-07-29
ES8306473A1 (en) 1983-06-01
AU543647B2 (en) 1985-04-26
NO812736L (en) 1982-02-15
ES514371A0 (en) 1983-05-01
ES514369A0 (en) 1983-05-01
ES514370A0 (en) 1983-06-01
AR231273A1 (en) 1984-10-31
AR229188A1 (en) 1983-06-30
JPS5759842A (en) 1982-04-10
PT73511A (en) 1981-09-01
AR231274A1 (en) 1984-10-31
KR840002266B1 (en) 1984-12-14
AR231278A1 (en) 1984-10-31
DD202691A5 (en) 1983-09-28
EP0045964A1 (en) 1982-02-17
GR74992B (en) 1984-07-12
IL63539A0 (en) 1981-11-30
DD202286A5 (en) 1983-09-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007