ES8304997A1 - Cephalosporin derivatives - Google Patents
Cephalosporin derivativesInfo
- Publication number
- ES8304997A1 ES8304997A1 ES514106A ES514106A ES8304997A1 ES 8304997 A1 ES8304997 A1 ES 8304997A1 ES 514106 A ES514106 A ES 514106A ES 514106 A ES514106 A ES 514106A ES 8304997 A1 ES8304997 A1 ES 8304997A1
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporin derivatives
- derivatives
- hydrazonocephem
- ylthio
- acetyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel hydrazonocephem derivatives of the general formula:- < IMAGE > wherein R is an acetyloxy or 1-methyl- 1H-tetrazol-5-ylthio radical and the pharmaceutically-acceptable, non- toxic salts thereof, in the sin and/or anti configuration, have antibacterial activity and can be incorporated into pharmaceutical compositions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8123033A IT1211080B (en) | 1981-07-21 | 1981-07-21 | BIOLOGICALLY ACTIVE HYDRAZONOCEFEM. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES514106A0 ES514106A0 (en) | 1983-04-01 |
ES8304997A1 true ES8304997A1 (en) | 1983-04-01 |
Family
ID=11203099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES514106A Expired ES8304997A1 (en) | 1981-07-21 | 1982-07-19 | Cephalosporin derivatives |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS5824589A (en) |
DE (1) | DE3227284A1 (en) |
ES (1) | ES8304997A1 (en) |
FR (1) | FR2510117B1 (en) |
GB (1) | GB2102423B (en) |
IT (1) | IT1211080B (en) |
PT (1) | PT75281A (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT381944B (en) * | 1984-04-10 | 1986-12-10 | Biochemie Gmbh | METHOD FOR PRODUCING CEPHALOSPORINANTIBIOTICS |
CN102988362B (en) | 2005-12-07 | 2014-11-05 | 巴斯利尔药物股份公司 | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors |
EP2105435A4 (en) * | 2007-01-10 | 2011-06-15 | Mitsubishi Tanabe Pharma Corp | Hydrazone derivative |
CN112010821A (en) * | 2020-09-29 | 2020-12-01 | 山东金城医药化工有限公司 | Recovery method of ethyl aminothiazoly loximate |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1208015A (en) * | 1967-03-23 | 1970-10-07 | Glaxo Lab Ltd | Cephalosporins |
GB1208014A (en) * | 1967-03-23 | 1970-10-07 | Glaxo Lab Ltd | Cephalosporins |
DK400074A (en) | 1973-10-01 | 1975-06-09 | Ciba Geigy Ag | |
IT1081809B (en) * | 1977-06-07 | 1985-05-21 | Isf Spa | HYDRAZE CEPHALOSPORINE |
DE2818263A1 (en) * | 1978-04-26 | 1979-11-08 | Bayer Ag | BETA LACTAMANTIBIOTICS |
-
1981
- 1981-07-21 IT IT8123033A patent/IT1211080B/en active
-
1982
- 1982-07-15 FR FR8212347A patent/FR2510117B1/en not_active Expired
- 1982-07-19 ES ES514106A patent/ES8304997A1/en not_active Expired
- 1982-07-20 PT PT75281A patent/PT75281A/en unknown
- 1982-07-20 JP JP57125241A patent/JPS5824589A/en active Pending
- 1982-07-20 GB GB08220930A patent/GB2102423B/en not_active Expired
- 1982-07-21 DE DE19823227284 patent/DE3227284A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES514106A0 (en) | 1983-04-01 |
FR2510117B1 (en) | 1985-07-05 |
PT75281A (en) | 1982-08-01 |
DE3227284A1 (en) | 1983-02-24 |
IT8123033A0 (en) | 1981-07-21 |
JPS5824589A (en) | 1983-02-14 |
FR2510117A1 (en) | 1983-01-28 |
IT1211080B (en) | 1989-09-29 |
GB2102423A (en) | 1983-02-02 |
GB2102423B (en) | 1985-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES477591A1 (en) | Cephem derivatives | |
ES8201166A1 (en) | Cephalosporin derivatives, their preparation and their use. | |
JPS5334794A (en) | Cephalosporin derivatives and their preparation | |
ES8102561A1 (en) | 1-Aryl-4- gamma -arylsulphonyl-3-aminopropoxy-1H-pyrazoles and their use as hypolipemiant and hypocholesterolemiant agents | |
ES469425A1 (en) | N-Alkyl-N-acyl derivatives of thienamycin | |
ES476109A1 (en) | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation. | |
ES8101606A1 (en) | Cephalosporin derivatives, their preparation and the corresponding pharmaceutical compositions. | |
ES8700246A1 (en) | Coumarin derivatives, pharmaceutical compositions containing the same, and the use thereof in the treatment of cancer. | |
ES476154A1 (en) | Cephalosporin compounds and formulations containing them for use in the treatment of bacterial infections and the preparation of the cephalosporin compounds. | |
ES8304997A1 (en) | Cephalosporin derivatives | |
ES8205810A1 (en) | Cephem compounds | |
DE3470313D1 (en) | Antibiotic, its preparation and its use | |
ES480762A1 (en) | Cephem derivatives, process for their preparation and pharmaceutical compositions containing them. | |
ES8800916A1 (en) | O-sulfated spiro beta -lactam hydroxamic acids | |
AU562643B2 (en) | N-arylpiperazine derivatives | |
SE7707366L (en) | PROCEDURE FOR THE PREPARATION OF 7ALFA-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES | |
ES422303A1 (en) | 1-Alkylideneaminouracil compounds and herbicidal compositions | |
AU554372B2 (en) | Dihydrothiazolo derivatives | |
AU511344B2 (en) | "7-(2-substituted-4-(4-hydroxy phenyl) -5 ketoterahydroimidazo-1-yl) - 3- substituted thiomethyl-3-cephem-4-carboxylic acid derivatives | |
JPS5384987A (en) | Cephalosporin-analogous antibiotics | |
JPS5387389A (en) | Novel cephalosporin derivative, pharmaceuticals containing the same, and its preparation | |
ES469426A1 (en) | Thienamycin derivatives | |
JPS5259188A (en) | Preparation of novel alkoxyt-substituted putterioine derivatives | |
JPS5321187A (en) | Cephalosporin compounds and their preparation | |
ES8302721A1 (en) | Cephalosporin derivatives, their preparation, compositions containing them, and their use in the treatment of diseases. |