ES8303300A1 - "procedimiento para la preparacion de nuevos 1-(acilamino-ariloxi-)2-hidroxi-3-alquinilaminopropanos". - Google Patents
"procedimiento para la preparacion de nuevos 1-(acilamino-ariloxi-)2-hidroxi-3-alquinilaminopropanos".Info
- Publication number
- ES8303300A1 ES8303300A1 ES509513A ES509513A ES8303300A1 ES 8303300 A1 ES8303300 A1 ES 8303300A1 ES 509513 A ES509513 A ES 509513A ES 509513 A ES509513 A ES 509513A ES 8303300 A1 ES8303300 A1 ES 8303300A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- treatment
- alkinyl
- acylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Manufacture Of Tobacco Products (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-(ACILAMINO-ARILOXI)-2-HIDROXI-3-ALQUINILAMINOPROPANOS Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R ES ALCOHILO C <- ; Y R , R Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE HIDROLISIS DE UN COMPUESTO DERIVADO DE OXAZOLIDINA, DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO POR TRATAMIENTO A REFLUJO DEL COMPUESTO DISUELTO EN ALCOHOL, EN PRESENCIA DE UNA AMINA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ARRITMIAS CARDIACAS Y POR SUS PROPIEDADES HIPOTENSORAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803009047 DE3009047A1 (de) | 1980-03-08 | 1980-03-08 | Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8303300A1 true ES8303300A1 (es) | 1983-02-01 |
ES509513A0 ES509513A0 (es) | 1983-02-01 |
Family
ID=6096693
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500154A Granted ES500154A0 (es) | 1980-03-08 | 1981-03-06 | Procedimiento para la preparacion de nuevos 1-(acilamino- ariloxi-) 2-hidroxi-3-alquinilaminopropanos |
ES509513A Granted ES509513A0 (es) | 1980-03-08 | 1982-02-11 | "procedimiento para la preparacion de nuevos 1-(acilamino-ariloxi-)2-hidroxi-3-alquinilaminopropanos". |
ES509514A Expired ES8302638A1 (es) | 1980-03-08 | 1982-02-11 | "procedimiento para la preparacion de nuevos 1-(acilamino-arloxi-)2-hidroxi-3-alquinilaminopropanos". |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500154A Granted ES500154A0 (es) | 1980-03-08 | 1981-03-06 | Procedimiento para la preparacion de nuevos 1-(acilamino- ariloxi-) 2-hidroxi-3-alquinilaminopropanos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES509514A Expired ES8302638A1 (es) | 1980-03-08 | 1982-02-11 | "procedimiento para la preparacion de nuevos 1-(acilamino-arloxi-)2-hidroxi-3-alquinilaminopropanos". |
Country Status (18)
Country | Link |
---|---|
US (1) | US4609672A (es) |
EP (1) | EP0035733B1 (es) |
JP (1) | JPS56139448A (es) |
AT (1) | ATE4639T1 (es) |
AU (1) | AU541492B2 (es) |
CA (1) | CA1150735A (es) |
DE (2) | DE3009047A1 (es) |
DK (1) | DK102581A (es) |
ES (3) | ES500154A0 (es) |
FI (1) | FI74272C (es) |
GB (1) | GB2071096B (es) |
GR (1) | GR74907B (es) |
IE (1) | IE52015B1 (es) |
IL (1) | IL62308A (es) |
NO (1) | NO150961C (es) |
NZ (1) | NZ196445A (es) |
PT (1) | PT72620B (es) |
ZA (1) | ZA811499B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3133719A1 (de) * | 1981-08-26 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue 1-aryloxy-3-alkinylamino-2-propanole und verfahren zu ihrer herstellung |
TR200100692T2 (tr) | 1998-09-10 | 2001-07-23 | Aventis Pharma Deutschland Gmbh | Otonom sinir sisteminin disfonksiyonlarının önlenmesinde Benzensulfonil (Tiyo) ürelerin kullanımı |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH546224A (en) * | 1969-08-08 | 1974-02-28 | Boehringer Sohn Ingelheim | 1-(2-nitrilophenoxy)-2-hydroxy-3-ethylamino - propane |
CH546227A (en) * | 1969-08-08 | 1974-02-28 | Boehringer Sohn Ingelheim | 1-(2-nitrilophenoxy)-2-hydroxy-3-ethylamino - propane |
DE2309887C2 (de) * | 1973-02-28 | 1983-11-10 | C.H. Boehringer Sohn, 6507 Ingelheim | 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen |
DE2403809C2 (de) * | 1974-01-26 | 1986-02-27 | C.H. Boehringer Sohn, 6507 Ingelheim | 1-Aryloxy-2-hydroxy-3-alkinylaminopropane und Verfahren zu ihrer Herstellung und pharmazeutische Präparate |
AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
DE3009036A1 (de) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung |
-
1980
- 1980-03-08 DE DE19803009047 patent/DE3009047A1/de not_active Withdrawn
-
1981
- 1981-03-03 AT AT81101498T patent/ATE4639T1/de not_active IP Right Cessation
- 1981-03-03 EP EP81101498A patent/EP0035733B1/de not_active Expired
- 1981-03-03 DE DE8181101498T patent/DE3160861D1/de not_active Expired
- 1981-03-05 NO NO810764A patent/NO150961C/no unknown
- 1981-03-05 PT PT72620A patent/PT72620B/pt unknown
- 1981-03-06 ZA ZA00811499A patent/ZA811499B/xx unknown
- 1981-03-06 ES ES500154A patent/ES500154A0/es active Granted
- 1981-03-06 FI FI810714A patent/FI74272C/fi not_active IP Right Cessation
- 1981-03-06 AU AU68157/81A patent/AU541492B2/en not_active Ceased
- 1981-03-06 GR GR64336A patent/GR74907B/el unknown
- 1981-03-06 NZ NZ196445A patent/NZ196445A/en unknown
- 1981-03-06 CA CA000372475A patent/CA1150735A/en not_active Expired
- 1981-03-06 GB GB8107115A patent/GB2071096B/en not_active Expired
- 1981-03-06 DK DK102581A patent/DK102581A/da not_active Application Discontinuation
- 1981-03-06 IE IE486/81A patent/IE52015B1/en unknown
- 1981-03-06 IL IL62308A patent/IL62308A/xx unknown
- 1981-03-06 JP JP3236681A patent/JPS56139448A/ja active Pending
-
1982
- 1982-02-11 ES ES509513A patent/ES509513A0/es active Granted
- 1982-02-11 ES ES509514A patent/ES8302638A1/es not_active Expired
-
1984
- 1984-06-25 US US06/623,960 patent/US4609672A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA1150735A (en) | 1983-07-26 |
FI810714L (fi) | 1981-09-09 |
AU541492B2 (en) | 1985-01-10 |
PT72620A (de) | 1981-04-01 |
PT72620B (de) | 1982-11-15 |
NO810764L (no) | 1981-09-09 |
ATE4639T1 (de) | 1983-09-15 |
ES8205396A1 (es) | 1982-06-01 |
EP0035733B1 (de) | 1983-09-14 |
EP0035733A1 (de) | 1981-09-16 |
FI74272C (fi) | 1988-01-11 |
JPS56139448A (en) | 1981-10-30 |
FI74272B (fi) | 1987-09-30 |
NO150961B (no) | 1984-10-08 |
GB2071096B (en) | 1983-09-14 |
ZA811499B (en) | 1982-11-24 |
GB2071096A (en) | 1981-09-16 |
IL62308A0 (en) | 1981-05-20 |
AU6815781A (en) | 1981-09-17 |
DE3160861D1 (en) | 1983-10-20 |
NO150961C (no) | 1985-01-16 |
IE52015B1 (en) | 1987-05-27 |
GR74907B (es) | 1984-07-12 |
ES500154A0 (es) | 1982-06-01 |
DE3009047A1 (de) | 1981-09-24 |
ES509514A0 (es) | 1983-01-16 |
DK102581A (da) | 1981-09-09 |
IL62308A (en) | 1984-12-31 |
ES509513A0 (es) | 1983-02-01 |
US4609672A (en) | 1986-09-02 |
NZ196445A (en) | 1984-05-31 |
ES8302638A1 (es) | 1983-01-16 |
IE810486L (en) | 1981-09-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8303300A1 (es) | "procedimiento para la preparacion de nuevos 1-(acilamino-ariloxi-)2-hidroxi-3-alquinilaminopropanos". | |
ES8205395A1 (es) | Procedimiento para preparar nuevos 1-(acilamino-ariloxi-)2- hidroxi-3-alquinilaminopropanos | |
ES8207502A1 (es) | Procedimiento para la preparacion de nuevos 1-ariloxi-3-al- cohilamino-2-propanoles |