ES8300775A1 - "procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c". - Google Patents
"procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c".Info
- Publication number
- ES8300775A1 ES8300775A1 ES508111A ES508111A ES8300775A1 ES 8300775 A1 ES8300775 A1 ES 8300775A1 ES 508111 A ES508111 A ES 508111A ES 508111 A ES508111 A ES 508111A ES 8300775 A1 ES8300775 A1 ES 8300775A1
- Authority
- ES
- Spain
- Prior art keywords
- cephamycin
- derivative
- preparation
- isolate
- unsatisfactory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN N-BENCENOSULFONIL DERIVADO DE LA CEFAMINICINA C, DE FORMULA (I). CONSISTE EN LA REACCION DE LA CEFAMICINA C EN DISOLUCION ACUOSA CON CLORURO DE BENCENOSULFONILO. LA REACCION SE LLEVA A CABO EN UN MEDIO DE PH COMPRENDIDO ENTRE 8,0 Y 10,5. EL PRODUCTO OBTENIDO SE PRECIPITA A PARTIR DE LA DISOLUCION ACUOSA POR AJUSTE DEL PH ENTRE 1 Y 3 MEDIANTE UN ACIDO INORGANICO FUERTE. >ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55170274A JPS5795992A (en) | 1980-12-04 | 1980-12-04 | Novel derivative of cephamycin c and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8300775A1 true ES8300775A1 (es) | 1982-11-01 |
ES508111A0 ES508111A0 (es) | 1982-11-01 |
Family
ID=15901899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES508111A Granted ES508111A0 (es) | 1980-12-04 | 1981-12-04 | "procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c". |
Country Status (5)
Country | Link |
---|---|
US (1) | US4495348A (es) |
EP (1) | EP0053919B1 (es) |
JP (1) | JPS5795992A (es) |
DE (1) | DE3174355D1 (es) |
ES (1) | ES508111A0 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6511962B1 (en) | 2000-07-17 | 2003-01-28 | Micrologix Biotech Inc. | Derivatives of laspartomycin and preparation and use thereof |
AU2001278933B2 (en) * | 2000-07-17 | 2006-05-25 | Migenix Inc. | Antimicrobial sulfonamide derivatives of lipopeptide antibiotics |
US6750199B2 (en) | 2000-07-17 | 2004-06-15 | Micrologix Biotech Inc. | Antimicrobial sulfonamide derivatives of lipopeptide antibiotics |
US6737403B2 (en) | 2000-07-17 | 2004-05-18 | Micrologix Biotech Inc. | Derivatives of laspartomycin and preparation and use thereof |
CN103421024B (zh) * | 2012-05-21 | 2016-08-03 | 上海医药工业研究院 | 制备头霉素c的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB143800A (en) * | 1919-11-24 | 1920-06-03 | Jules Delort | Improvements in and relating to milk churns |
CH541579A (de) * | 1969-05-13 | 1973-09-15 | Ciba Geigy Ag | Verfahren zur Abtrennung von Cephalosporin C aus Rohlösungen |
US4173702A (en) * | 1969-08-12 | 1979-11-06 | Eli Lilly And Company | 7-(5-Amino-5-carboxyvaler-amido)-3-(carbamoyloxymethyl)-7-methoxy-3-cephem-4-carboxylic acid |
US4302578A (en) * | 1970-12-09 | 1981-11-24 | Merck & Co., Inc. | Cephalosporin antibiotics |
JPS4950593A (es) * | 1972-09-19 | 1974-05-16 | ||
GB1489231A (en) * | 1974-02-20 | 1977-10-19 | Alfa Farmaceutici Spa | Process for the recovery of cephalosporin c and derivatives thereof |
US4053286A (en) * | 1974-09-23 | 1977-10-11 | Merck & Co., Inc. | Process for the preparation of cephalosporin antibiotics |
US4283492A (en) * | 1975-06-21 | 1981-08-11 | Fujisawa Pharmaceutical Co., Ltd. | Production of antibiotics WS-3442 A, B, C, D and E, and their acyl derivatives |
JPS6052709B2 (ja) * | 1977-12-28 | 1985-11-20 | 三共株式会社 | セフアマイシン誘導体の製法 |
JPS54141794A (en) * | 1978-04-04 | 1979-11-05 | Nippon Kayaku Co Ltd | Preparation of n-acylcephamycin c and its salt with organic base |
-
1980
- 1980-12-04 JP JP55170274A patent/JPS5795992A/ja active Granted
-
1981
- 1981-11-24 US US06/324,475 patent/US4495348A/en not_active Expired - Fee Related
- 1981-12-03 EP EP81305716A patent/EP0053919B1/en not_active Expired
- 1981-12-03 DE DE8181305716T patent/DE3174355D1/de not_active Expired
- 1981-12-04 ES ES508111A patent/ES508111A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS628118B2 (es) | 1987-02-20 |
DE3174355D1 (en) | 1986-05-15 |
EP0053919B1 (en) | 1986-04-09 |
US4495348A (en) | 1985-01-22 |
ES508111A0 (es) | 1982-11-01 |
JPS5795992A (en) | 1982-06-15 |
EP0053919A3 (en) | 1983-01-26 |
EP0053919A2 (en) | 1982-06-16 |
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