ES8207584A1 - Procedimiento para el desdoblamiento enzimatico de acido d, l-2-amino-4-metilfosfinobutirico. - Google Patents

Procedimiento para el desdoblamiento enzimatico de acido d, l-2-amino-4-metilfosfinobutirico.

Info

Publication number
ES8207584A1
ES8207584A1 ES508034A ES508034A ES8207584A1 ES 8207584 A1 ES8207584 A1 ES 8207584A1 ES 508034 A ES508034 A ES 508034A ES 508034 A ES508034 A ES 508034A ES 8207584 A1 ES8207584 A1 ES 8207584A1
Authority
ES
Spain
Prior art keywords
amino
phosphino
methyl
butyric acid
enzymatic preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508034A
Other languages
English (en)
Other versions
ES508034A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8207584A1 publication Critical patent/ES8207584A1/es
Publication of ES508034A0 publication Critical patent/ES508034A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA EL DESDOBLAMIENTO ENZIMATICO DE ACIDO D, L-2-AMINO-4/MESTILFOSFINOBUTIRICO. CONSISTE EN UN TRATAR LOS DERIVADOS N-ARACETILICOS CON UNA PENICILINA-G-ACILASA OBTENIDA A PARTIR DE E. CLI ATCC 11105. DICHA PENICILIN-G-ACILASA SE PRESENTA COMO LIOFILIZADO LIBRE FIJADO A UN SOPORTE. SE OBTIENE UNA MEZCLA DE L-PTC Y N/FENACETIL-D+PTC, ASI COMO ACIDO FINELACETICO, A PARTIR DE LOS CUAL SE PUEDE SEPARAR POR PROCEDIMIENTOS CONOCIDOS EL L-PTC.
ES508034A 1980-12-23 1981-12-16 Procedimiento para el desdoblamiento enzimatico de acido d, l-2-amino-4-metilfosfinobutirico. Granted ES508034A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3048612A DE3048612C2 (de) 1980-12-23 1980-12-23 "Verfahren zur enzymatischen Trennung von L-2-Ami no-4-methylphosphinobuttersäure"

Publications (2)

Publication Number Publication Date
ES8207584A1 true ES8207584A1 (es) 1982-10-01
ES508034A0 ES508034A0 (es) 1982-10-01

Family

ID=6120041

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508034A Granted ES508034A0 (es) 1980-12-23 1981-12-16 Procedimiento para el desdoblamiento enzimatico de acido d, l-2-amino-4-metilfosfinobutirico.

Country Status (21)

Country Link
US (1) US4389488A (es)
EP (1) EP0054897B1 (es)
JP (1) JPS57138394A (es)
AT (1) ATE14597T1 (es)
AU (1) AU547636B2 (es)
BR (1) BR8108346A (es)
CA (1) CA1172981A (es)
CS (1) CS224638B2 (es)
DD (1) DD201907A5 (es)
DE (2) DE3048612C2 (es)
DK (1) DK571481A (es)
ES (1) ES508034A0 (es)
HU (1) HU189552B (es)
IL (1) IL64623A (es)
MA (1) MA19362A1 (es)
OA (1) OA06973A (es)
PL (1) PL234314A1 (es)
PT (1) PT74188B (es)
SU (1) SU1246897A3 (es)
ZA (1) ZA818859B (es)
ZW (1) ZW30581A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3334849A1 (de) * 1983-09-27 1985-04-04 Hoechst Ag, 6230 Frankfurt Verfahren zur racemisierung optisch aktiver aminosaeuren
DE3435156A1 (de) * 1984-09-25 1986-04-03 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung der stereoisomeren von 1-amino-alkylphosphonsaeuren oder 1-aminoalkylphosphinsaeuren
DE3724722A1 (de) * 1987-07-25 1989-02-16 Hoechst Ag Verbessertes verfahren zur enzymatischen herstellung von l-2-amino-4-methylphosphinobuttersaeure
DE3817191A1 (de) * 1988-05-20 1989-11-30 Hoechst Ag Verfahren zur racemisierung von optisch aktiver d-2-n-phenacetylamino-4- methylphosphinobuttersaeure
DE3817956A1 (de) * 1988-05-27 1989-12-07 Hoechst Ag Verfahren zur herstellung phosphorhaltiger l-aminosaeuren sowie ihrer ester und n-derivate
US5081024A (en) * 1988-09-05 1992-01-14 Nissan Chemical Industries, Ltd. Process for producing optically active amino acids
DE3903446A1 (de) * 1989-02-06 1990-10-18 Hoechst Ag Verfahren zur enzymatischen trennung von 2-amino-4-methylphosphinobuttersaeurederivaten
US5057607A (en) * 1990-06-08 1991-10-15 Eli Lilly And Company Enantiomerically selective biocatalyzed acylation
TW353663B (en) * 1991-04-06 1999-03-01 Hoechst Ag Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process
DE4422045A1 (de) * 1994-06-26 1996-01-04 Hoechst Schering Agrevo Gmbh Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten
AU2003207323B2 (en) * 2002-02-26 2007-09-13 Syngenta Limited A method of selectively producing male or female sterile plants
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN108484665B (zh) * 2018-04-16 2020-06-23 浙江工业大学 一种从酶转化液中分离提取l-草铵膦的方法
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN110343734B (zh) * 2019-06-14 2021-03-23 浙江工业大学 一种l-草铵膦化学酶法生产方法
MX2023011615A (es) 2021-04-01 2023-10-11 Basf Se Metodos para preparar l-glufosinato.
CN114277080B (zh) * 2021-12-22 2023-10-03 河北威远生物化工有限公司 一种酶拆分法制备l-草铵膦的工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1369462A (en) 1971-11-23 1974-10-09 Beecham Group Ltd Enzymic resolution of racemic n-acyl-dl-amino acids
JPS5547630A (en) * 1978-10-02 1980-04-04 Meiji Seika Kaisha Ltd Optical resolution of phosphorus-containing amino acid
US4226941A (en) * 1979-09-27 1980-10-07 Meiji Seika Kaisha, Ltd. Process for the optical resolution of d,l-2-amino-4-methylphosphinobutyric acid

Also Published As

Publication number Publication date
DE3048612A1 (de) 1982-07-01
CA1172981A (en) 1984-08-21
BR8108346A (pt) 1982-10-13
AU7875181A (en) 1982-07-01
AU547636B2 (en) 1985-10-31
PT74188B (en) 1983-11-08
JPS57138394A (en) 1982-08-26
DK571481A (da) 1982-06-24
IL64623A0 (en) 1982-03-31
SU1246897A3 (ru) 1986-07-23
EP0054897A2 (de) 1982-06-30
EP0054897A3 (en) 1982-09-08
PL234314A1 (es) 1982-07-05
DE3048612C2 (de) 1982-12-02
US4389488A (en) 1983-06-21
PT74188A (en) 1982-01-01
OA06973A (fr) 1983-07-31
CS224638B2 (en) 1984-01-16
EP0054897B1 (de) 1985-07-31
IL64623A (en) 1985-04-30
ZW30581A1 (en) 1982-07-14
JPH0218072B2 (es) 1990-04-24
DD201907A5 (de) 1983-08-17
HU189552B (en) 1986-07-28
MA19362A1 (fr) 1982-07-01
ATE14597T1 (de) 1985-08-15
DE3171623D1 (en) 1985-09-05
ES508034A0 (es) 1982-10-01
ZA818859B (en) 1982-11-24

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