ES8207536A1 - A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8207536A1
ES8207536A1 ES505214A ES505214A ES8207536A1 ES 8207536 A1 ES8207536 A1 ES 8207536A1 ES 505214 A ES505214 A ES 505214A ES 505214 A ES505214 A ES 505214A ES 8207536 A1 ES8207536 A1 ES 8207536A1
Authority
ES
Spain
Prior art keywords
translation
derivatives
procedure
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505214A
Other languages
Spanish (es)
Other versions
ES505214A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES505214A0 publication Critical patent/ES505214A0/en
Publication of ES8207536A1 publication Critical patent/ES8207536A1/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A PROCEDURE FOR THE PREPARATION OF IMIDAZO-DIACEPINA DERIVATIVES. IT CONSISTS OF TRANS-ESTERIFYING A COMPOUND OF GENERAL FORMULA (I) TO OBTAIN THE COMPOUND (II) WHICH, IF DESIRED, IS TRANSFORMED IN THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT; R2 IS HYDROGEN AND R3 IS HYDROGEN OR LOWER ALKYL, WHILE R2 AND R3 TOGETHER REPRESENT TRIMYTILENE OR PROPYLENE; R4 IS METHYL, ETHYL, ISOPROPYL OR2-HYDROXY-ETHYL. TRANS-ESTERIFICATION TAKES PLACE BY REACTING COMPOUND (I) WITH AN ALCOHOL, SUCH AS METHANOL, ETHANOL, ISIPROPANOL OR ETHYLENGLYCOL AT ROOM TEMPERATURE OR WHILE HEATING BETWEEN 25 AND 150 DEGREES. SUCH REACTION TAKES PLACE PREFERABLY IN THE PRESENCE OF A BASE. (Machine-translation by Google Translate, not legally binding)
ES505214A 1979-10-04 1981-09-04 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding) Expired ES8207536A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH897279 1979-10-04
CH897179 1979-10-04
CH1066579 1979-11-30
CH1066479 1979-11-30

Publications (2)

Publication Number Publication Date
ES505214A0 ES505214A0 (en) 1982-10-01
ES8207536A1 true ES8207536A1 (en) 1982-10-01

Family

ID=27429184

Family Applications (4)

Application Number Title Priority Date Filing Date
ES495598A Expired ES8201163A1 (en) 1979-10-04 1980-10-03 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)
ES505212A Granted ES505212A0 (en) 1979-10-04 1981-09-04 A PROCEDURE FOR THE PREPARATION OF IMIDA-ZODIACEPINE DERIVATIVES
ES505211A Expired ES8207534A1 (en) 1979-10-04 1981-09-04 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)
ES505214A Expired ES8207536A1 (en) 1979-10-04 1981-09-04 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES495598A Expired ES8201163A1 (en) 1979-10-04 1980-10-03 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)
ES505212A Granted ES505212A0 (en) 1979-10-04 1981-09-04 A PROCEDURE FOR THE PREPARATION OF IMIDA-ZODIACEPINE DERIVATIVES
ES505211A Expired ES8207534A1 (en) 1979-10-04 1981-09-04 A procedure for the preparation of imidazodiacepine derivatives (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
AT (1) ATE7497T1 (en)
ES (4) ES8201163A1 (en)

Also Published As

Publication number Publication date
ES495598A0 (en) 1981-12-16
ES8300766A1 (en) 1982-11-16
ES8201163A1 (en) 1981-12-16
ES505214A0 (en) 1982-10-01
ES505212A0 (en) 1982-11-16
ES505211A0 (en) 1982-10-01
ES8207534A1 (en) 1982-10-01
ATE7497T1 (en) 1984-06-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020418