ES8206548A1 - Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina. - Google Patents

Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina.

Info

Publication number
ES8206548A1
ES8206548A1 ES507346A ES507346A ES8206548A1 ES 8206548 A1 ES8206548 A1 ES 8206548A1 ES 507346 A ES507346 A ES 507346A ES 507346 A ES507346 A ES 507346A ES 8206548 A1 ES8206548 A1 ES 8206548A1
Authority
ES
Spain
Prior art keywords
lincomycin
clindamycin
analogue
reaction
lincosamidina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507346A
Other languages
English (en)
Other versions
ES507346A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8206548A1 publication Critical patent/ES8206548A1/es
Publication of ES507346A0 publication Critical patent/ES507346A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16Lincomycin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCIO DE ANALOGOS DE LINCOMICINA Y CLINDAMICINA. CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO DE FORMULA (I), EN LA QUEZ X ES 7(S)-CLOROMETIL-1-TIO-A-LINCOSAMIDINA. LA REACCION SE LEVA A CABO POR TRATAMIENTO CON HIDROGENO EN UN HIDROGENADOR PARR A UNAS3 ATMOSFERAS, EN PRESENCIA DE CATALIZADOR DE OXIDO DE PLATINO. EL PRODUCTO SE SEPARA POR FILTRACION Y SE PURIFICA POR METODOS CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS CONO ANTIBIOTICOS
ES507346A 1979-11-23 1981-11-20 Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina. Granted ES507346A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9665279A 1979-11-23 1979-11-23

Publications (2)

Publication Number Publication Date
ES8206548A1 true ES8206548A1 (es) 1982-08-16
ES507346A0 ES507346A0 (es) 1982-08-16

Family

ID=22258400

Family Applications (2)

Application Number Title Priority Date Filing Date
ES507346A Granted ES507346A0 (es) 1979-11-23 1981-11-20 Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina.
ES507345A Granted ES507345A0 (es) 1979-11-23 1981-11-20 Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES507345A Granted ES507345A0 (es) 1979-11-23 1981-11-20 Procedimiento para la preparacion de nuevos analogos utiles de lincomicina y clindamicina.

Country Status (4)

Country Link
JP (2) JPS5687597A (es)
BE (1) BE886301A (es)
ES (2) ES507346A0 (es)
ZA (1) ZA806438B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0411537A (pt) * 2003-06-17 2006-08-01 Vicuron Pharm Inc derivados de lincomicina que possuem atividade antibacteriana

Also Published As

Publication number Publication date
JPS63225392A (ja) 1988-09-20
ES8206547A1 (es) 1982-09-01
ES507345A0 (es) 1982-09-01
JPS5687597A (en) 1981-07-16
JPS6338037B2 (es) 1988-07-28
JPH0141157B2 (es) 1989-09-04
ES507346A0 (es) 1982-08-16
ZA806438B (en) 1981-10-28
BE886301A (fr) 1981-05-21

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Legal Events

Date Code Title Description
PC1A Transfer granted