ES8203828A1 - Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas - Google Patents

Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas

Info

Publication number
ES8203828A1
ES8203828A1 ES501744A ES501744A ES8203828A1 ES 8203828 A1 ES8203828 A1 ES 8203828A1 ES 501744 A ES501744 A ES 501744A ES 501744 A ES501744 A ES 501744A ES 8203828 A1 ES8203828 A1 ES 8203828A1
Authority
ES
Spain
Prior art keywords
bis
alkyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501744A
Other languages
English (en)
Other versions
ES501744A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Publication of ES501744A0 publication Critical patent/ES501744A0/es
Publication of ES8203828A1 publication Critical patent/ES8203828A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/06Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BIS-(FENOXIACETATOS SUSTITUIDOS) DE N-ALCOHILDIALCANOLAMINAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X ES CLORO, FLUOR O TRIFLUOROMETILO, R ES UN ALCOHILO INFERIOR Y N VALE DE 1 A 3. CONSISTE EN LA REACCION DE UNA N-ALCOHILDIALCANOLAMINA DE FORMULA R-N-((CH2)NOH)2, CON UNA PROPORCION APROXIMADAMENTE DOBLE, UN ACIDO FENOXIACETICO DE FORMULA (II), O EL ESTER, CLORURO DE ACIDO O ANHIDRIDO, EN LA QUE X TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO ALIFATICO O AROMATICO INERTE, A LA TEMPERATURA DE REFLUJO DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ESTIMULANTES DE LA ACTIVIDAD NERVIOSA CENTRAL, POR SU EFECTO ANTIAGREGADOR DE PLAQUETAS Y DIURETICO.
ES501744A 1980-04-30 1981-04-29 Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas Expired ES8203828A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8009886A FR2481697A1 (fr) 1980-04-30 1980-04-30 Bis(phenoxyacetates substitues) de n-alkyl-dialcanolamines, procede d'obtention, applications a titre de medicaments et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
ES501744A0 ES501744A0 (es) 1982-04-01
ES8203828A1 true ES8203828A1 (es) 1982-04-01

Family

ID=9241574

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501744A Expired ES8203828A1 (es) 1980-04-30 1981-04-29 Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas

Country Status (7)

Country Link
US (1) US4399299A (es)
EP (1) EP0039294B1 (es)
JP (1) JPS56169656A (es)
AT (1) ATE6423T1 (es)
DE (1) DE3162410D1 (es)
ES (1) ES8203828A1 (es)
FR (1) FR2481697A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2771477A (en) * 1952-06-06 1956-11-20 Thompson Hayward Chemical Comp Low volatile herbicidal compositions
SE337383B (es) * 1965-01-05 1971-08-09 Yoshitomi Pharmaceutical
FR2085634A1 (en) * 1970-04-14 1971-12-31 Synthelabo 2-(parachlorophenoxy)-2-methyl propionic esters - hypolipemics and hypocholesterolemics

Also Published As

Publication number Publication date
JPS56169656A (en) 1981-12-26
FR2481697A1 (fr) 1981-11-06
FR2481697B1 (es) 1984-02-17
EP0039294A1 (fr) 1981-11-04
DE3162410D1 (en) 1984-04-05
JPH029575B2 (es) 1990-03-02
ES501744A0 (es) 1982-04-01
EP0039294B1 (fr) 1984-02-29
US4399299A (en) 1983-08-16
ATE6423T1 (de) 1984-03-15

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