ES8203828A1 - Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas - Google Patents
Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminasInfo
- Publication number
- ES8203828A1 ES8203828A1 ES501744A ES501744A ES8203828A1 ES 8203828 A1 ES8203828 A1 ES 8203828A1 ES 501744 A ES501744 A ES 501744A ES 501744 A ES501744 A ES 501744A ES 8203828 A1 ES8203828 A1 ES 8203828A1
- Authority
- ES
- Spain
- Prior art keywords
- bis
- alkyl
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE BIS-(FENOXIACETATOS SUSTITUIDOS) DE N-ALCOHILDIALCANOLAMINAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X ES CLORO, FLUOR O TRIFLUOROMETILO, R ES UN ALCOHILO INFERIOR Y N VALE DE 1 A 3. CONSISTE EN LA REACCION DE UNA N-ALCOHILDIALCANOLAMINA DE FORMULA R-N-((CH2)NOH)2, CON UNA PROPORCION APROXIMADAMENTE DOBLE, UN ACIDO FENOXIACETICO DE FORMULA (II), O EL ESTER, CLORURO DE ACIDO O ANHIDRIDO, EN LA QUE X TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO ALIFATICO O AROMATICO INERTE, A LA TEMPERATURA DE REFLUJO DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ESTIMULANTES DE LA ACTIVIDAD NERVIOSA CENTRAL, POR SU EFECTO ANTIAGREGADOR DE PLAQUETAS Y DIURETICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8009886A FR2481697A1 (fr) | 1980-04-30 | 1980-04-30 | Bis(phenoxyacetates substitues) de n-alkyl-dialcanolamines, procede d'obtention, applications a titre de medicaments et compositions pharmaceutiques les contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
ES501744A0 ES501744A0 (es) | 1982-04-01 |
ES8203828A1 true ES8203828A1 (es) | 1982-04-01 |
Family
ID=9241574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES501744A Expired ES8203828A1 (es) | 1980-04-30 | 1981-04-29 | Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas |
Country Status (7)
Country | Link |
---|---|
US (1) | US4399299A (es) |
EP (1) | EP0039294B1 (es) |
JP (1) | JPS56169656A (es) |
AT (1) | ATE6423T1 (es) |
DE (1) | DE3162410D1 (es) |
ES (1) | ES8203828A1 (es) |
FR (1) | FR2481697A1 (es) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2771477A (en) * | 1952-06-06 | 1956-11-20 | Thompson Hayward Chemical Comp | Low volatile herbicidal compositions |
SE337383B (es) * | 1965-01-05 | 1971-08-09 | Yoshitomi Pharmaceutical | |
FR2085634A1 (en) * | 1970-04-14 | 1971-12-31 | Synthelabo | 2-(parachlorophenoxy)-2-methyl propionic esters - hypolipemics and hypocholesterolemics |
-
1980
- 1980-04-30 FR FR8009886A patent/FR2481697A1/fr active Granted
-
1981
- 1981-04-21 US US06/256,167 patent/US4399299A/en not_active Expired - Fee Related
- 1981-04-28 AT AT81400671T patent/ATE6423T1/de not_active IP Right Cessation
- 1981-04-28 EP EP81400671A patent/EP0039294B1/fr not_active Expired
- 1981-04-28 DE DE8181400671T patent/DE3162410D1/de not_active Expired
- 1981-04-29 ES ES501744A patent/ES8203828A1/es not_active Expired
- 1981-04-30 JP JP6616681A patent/JPS56169656A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS56169656A (en) | 1981-12-26 |
FR2481697A1 (fr) | 1981-11-06 |
FR2481697B1 (es) | 1984-02-17 |
EP0039294A1 (fr) | 1981-11-04 |
DE3162410D1 (en) | 1984-04-05 |
JPH029575B2 (es) | 1990-03-02 |
ES501744A0 (es) | 1982-04-01 |
EP0039294B1 (fr) | 1984-02-29 |
US4399299A (en) | 1983-08-16 |
ATE6423T1 (de) | 1984-03-15 |
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