ES8200093A1 - Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas. - Google Patents

Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas.

Info

Publication number
ES8200093A1
ES8200093A1 ES495422A ES495422A ES8200093A1 ES 8200093 A1 ES8200093 A1 ES 8200093A1 ES 495422 A ES495422 A ES 495422A ES 495422 A ES495422 A ES 495422A ES 8200093 A1 ES8200093 A1 ES 8200093A1
Authority
ES
Spain
Prior art keywords
arylsulfonyl
propenyl
propyl
alkyl
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495422A
Other languages
English (en)
Other versions
ES495422A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES495422A0 publication Critical patent/ES495422A0/es
Publication of ES8200093A1 publication Critical patent/ES8200093A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-(2-(ALQUIL Y ARILSULFONIL)-2-PROPENIL Y PROPIL)PIPERIDINAS DE FORMULA (I), U SUS SALES DE ADICION DE ACIDO, DONDE R3, R4 Y M PUEDEN SER DIFERENTES RADICALES Y A ES UN RADICAL DE FORMULA (II), DONDE R, R1 Y R2 SON DIFERENTES RADICALES. UN COMPUESTO DE FORMULA (III) SE HACE REACCIONAR CON OTRO DE FORMULA RSO2CH2COOH. EL COMPUESTO OBTENIDO SE HACE REACCIONAR CON EL REPRESENTADO POR LA FORMULA (IV) PARA OBTENER EL COMPUESTO DESEADO. DE APLICACION EN LA PROTECCION DE PRODUCTOS INDUSTRIALES CONTRA LA ACCION DETERIORANTE DE BASTERIAS Y HONGOS Y EN COMPOSICIONES ANTIINFLAMATORIAS.
ES495422A 1979-09-27 1980-09-26 Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas. Expired ES8200093A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/079,281 US4244963A (en) 1979-09-27 1979-09-27 1-[2-(Alkyl and arylsulfonyl)-2-propenyl and propyl] substituted piperidines useful as antimicrobial and antiinflammatory agents

Publications (2)

Publication Number Publication Date
ES495422A0 ES495422A0 (es) 1981-10-16
ES8200093A1 true ES8200093A1 (es) 1981-10-16

Family

ID=22149549

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495422A Expired ES8200093A1 (es) 1979-09-27 1980-09-26 Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas.

Country Status (7)

Country Link
US (1) US4244963A (es)
EP (1) EP0027895A1 (es)
JP (1) JPS5657765A (es)
DK (1) DK407080A (es)
ES (1) ES8200093A1 (es)
GR (1) GR70064B (es)
PT (1) PT71828B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668692A (en) * 1984-05-07 1987-05-26 Noorlander Daniel O Dry powdered germicide and healing compositions
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US5179095A (en) * 1986-02-26 1993-01-12 Eisai Co., Ltd. Piperidine derivative and pharmaceutical composition containing the same
NZ239022A (en) * 1990-07-25 1993-11-25 Merrell Dow Pharma Piperidyl ethers and thioethers; preparatory processes and pharmaceutical compositions
US5348964A (en) * 1990-07-25 1994-09-20 Merrell Dow Pharmaceuticals Inc. Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487469A (en) * 1965-02-26 1969-12-30 Ciba Geigy Corp 1,2-diaryl-3-(aminomethyl)-3-buten-2-ols and their acyl derivatives
US4145426A (en) * 1977-07-18 1979-03-20 Merck & Co., Inc. Anti-microbial piperidino butan-2-ones

Also Published As

Publication number Publication date
DK407080A (da) 1981-03-28
JPS5657765A (en) 1981-05-20
ES495422A0 (es) 1981-10-16
US4244963A (en) 1981-01-13
GR70064B (es) 1982-07-26
EP0027895A1 (en) 1981-05-06
PT71828B (en) 1982-03-26
PT71828A (en) 1980-10-01

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