ES8106481A1 - Un procedimiento para la preparacion de derivados de etanol-amina. - Google Patents

Un procedimiento para la preparacion de derivados de etanol-amina.

Info

Publication number
ES8106481A1
ES8106481A1 ES494853A ES494853A ES8106481A1 ES 8106481 A1 ES8106481 A1 ES 8106481A1 ES 494853 A ES494853 A ES 494853A ES 494853 A ES494853 A ES 494853A ES 8106481 A1 ES8106481 A1 ES 8106481A1
Authority
ES
Spain
Prior art keywords
group
hydrogen
methyl
atom
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494853A
Other languages
English (en)
Other versions
ES494853A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES494853A0 publication Critical patent/ES494853A0/es
Publication of ES8106481A1 publication Critical patent/ES8106481A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE ETANOL-AMINA. CONSISTE EN SOMETER A REDUCCION A UN COMPUESTO DE FORMULA GENERAL (I) O SU ESTER O AMIDA; SIENDO V. -CHOH-CH2-N=CR5-; -CHOH-CH2-NH-C(OH)R5; O -CO-CH=N-C(R5)R6-. OPCIONALMENTE SE PUEDE FORMAR UNA AMIDA ESTER O SAL DEL COMPUESTO OBTENIDO EN LA ETAPA ANTERIOR. LA COMPOSICION SE PRESENTA CON UN VEHICULO TAL COMO UN DILUYENTE, AGLUTINANTE, CARGA, DESINTEGRANTE, AGENTE HUMECTANTE, LUBRICANTE, COLORANTE, AGENTE QUE DA SABOR O SIMILARES; ENTRE ELLOS SE EMPLEAN LA CELULOSA MICROCRISTALINA, EL ALMIDON, EL ALMIDON GLICOLATO SODICO, POLIVINILPIRROLIDONA, ESTEARATO DE MAGNESIO, LAURILSULFATO SODICO Y SACAROSA. *FORMULA* ACTIVIDAD ANTIOBESIDAD Y ANTIHIPERGICEMICA.
ES494853A 1979-09-06 1980-09-05 Un procedimiento para la preparacion de derivados de etanol-amina. Expired ES8106481A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7931006 1979-09-06
GB8016348 1980-05-16

Publications (2)

Publication Number Publication Date
ES494853A0 ES494853A0 (es) 1981-08-16
ES8106481A1 true ES8106481A1 (es) 1981-08-16

Family

ID=26272782

Family Applications (2)

Application Number Title Priority Date Filing Date
ES494853A Expired ES8106481A1 (es) 1979-09-06 1980-09-05 Un procedimiento para la preparacion de derivados de etanol-amina.
ES501805A Granted ES501805A0 (es) 1979-09-06 1981-04-30 Un procedimiento para la preparacion de derivados de la eta-nolamina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES501805A Granted ES501805A0 (es) 1979-09-06 1981-04-30 Un procedimiento para la preparacion de derivados de la eta-nolamina

Country Status (9)

Country Link
US (1) US4309443A (es)
EP (1) EP0025331B1 (es)
AU (1) AU538584B2 (es)
CA (1) CA1153010A (es)
DE (1) DE3062216D1 (es)
DK (1) DK377680A (es)
ES (2) ES8106481A1 (es)
IL (1) IL60960A0 (es)
NZ (1) NZ194828A (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2096988B (en) * 1980-11-20 1984-08-01 Beecham Group Ltd Aromatic hydroxyamines
EP0063004A1 (en) * 1981-04-09 1982-10-20 Beecham Group Plc Secondary amines, processes for their preparation, and pharmaceutical compositions containing them
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
US5245053A (en) * 1990-05-04 1993-09-14 American Cyanamid Company Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles
US5151439A (en) * 1990-05-04 1992-09-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
GB9111426D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
US5300298A (en) * 1992-05-06 1994-04-05 The Pennsylvania Research Corporation Methods of treating obesity with purine related compounds
CN1129443A (zh) * 1993-06-14 1996-08-21 美国辉瑞有限公司 仲胺用作治糖尿病和治肥胖病药物
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US6075040A (en) 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
EP0801060A1 (en) * 1996-04-09 1997-10-15 Pfizer Inc. Heterocyclic Beta-3 Adrenergenic Agonists
ES2171839T3 (es) 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
US7884228B1 (en) * 2008-05-06 2011-02-08 Alcon, Inc. UV-absorbers for ophthalmic lens materials

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643262C3 (de) * 1967-12-13 1975-06-26 C.H. Boehringer Sohn, 6507 Ingelheim i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3836666A (en) * 1969-07-23 1974-09-17 Boehringer Sohn Ingelheim Pharmaceutical compositions containing certain 1-(cyano-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propanes and method of use
FR2132570B1 (es) * 1971-04-09 1974-08-02 Lipha
US3818101A (en) * 1972-08-28 1974-06-18 Smithkline Corp Methods for improving the feed intake of meat producing animals
US3857873A (en) * 1974-02-11 1974-12-31 Warner Lambert Co 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
DE2460689C3 (de) * 1974-12-20 1980-06-26 Klinge Pharma Gmbh & Co, 8000 Muenchen 13-disubstituierte Propanol-(2)-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DK148576A (da) * 1975-04-18 1976-10-19 Boehringer Mannheim Gmbh Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE2606140A1 (de) * 1976-02-17 1977-08-25 Boehringer Sohn Ingelheim Neue derivate des 2-phenyl-2-hydroxyaethylamins
US4146638A (en) * 1976-02-17 1979-03-27 Boehringer Ingelheim Gmbh N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes

Also Published As

Publication number Publication date
ES8204984A1 (es) 1982-05-16
DE3062216D1 (en) 1983-04-07
CA1153010A (en) 1983-08-30
ES494853A0 (es) 1981-08-16
EP0025331A1 (en) 1981-03-18
US4309443A (en) 1982-01-05
DK377680A (da) 1981-03-07
EP0025331B1 (en) 1983-03-02
NZ194828A (en) 1983-05-31
ES501805A0 (es) 1982-05-16
AU538584B2 (en) 1984-08-23
IL60960A0 (en) 1980-11-30
AU6204980A (en) 1981-03-12

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