ES8104242A1 - Un procedimiento para la preparacion de nuevos derivados de hidantoina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de hidantoina.Info
- Publication number
- ES8104242A1 ES8104242A1 ES487848A ES487848A ES8104242A1 ES 8104242 A1 ES8104242 A1 ES 8104242A1 ES 487848 A ES487848 A ES 487848A ES 487848 A ES487848 A ES 487848A ES 8104242 A1 ES8104242 A1 ES 8104242A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- alkyl
- hydantoin derivatives
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE FORMULA (I), O UNA SAL DE LOS MISMO, DONDE R1, R2, R3 Y R7 PUEDEN SER DIVERSOS TIPOS DE RADICALES; X ES OXIGENO O AZUFRE O =C=X ES =CH2; Y ES -CH2-CH2 O -CH=CH-, Y N PUEDE TENER LOS VALORES DE 1 A 5. EL PROCEDIMIENTO CONSISTE, FUNDAMENTALMENTE EN LA CICLACION AL COMPUESTO DE FORMULA (I) DE UN COMPUESTO DE FORMULA (II), EN LA QUE R1, R2, R3, R7, X, Y Y N TIENEN EL MISMO SIGNIFICADO ANTERIRO R5 ES UN RADICAL DE MENOS DE 12 ATOMOS DE CARBONO Y R6 ES UN HIDROXI PROTEGIDO. OPCIONALMENTE, EL COMPUESTO DE FORMULA (II) PUEDE PREPARARSE <<IN SITU>>. ESTOS COMPUESTOS SON UTILES COMO MEDICAMENTOS CON ACTIVIDAD FARMACOLOGICA EN DIVERSOS CAMPOS. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7901887 | 1979-01-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8104242A1 true ES8104242A1 (es) | 1981-04-16 |
ES487848A0 ES487848A0 (es) | 1981-04-16 |
Family
ID=10502599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487848A Granted ES487848A0 (es) | 1979-01-18 | 1980-01-18 | Un procedimiento para la preparacion de nuevos derivados de hidantoina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4413002A (es) |
EP (1) | EP0014076B1 (es) |
JP (1) | JPS55100371A (es) |
AU (1) | AU5472080A (es) |
DE (1) | DE3061830D1 (es) |
DK (1) | DK17380A (es) |
ES (1) | ES487848A0 (es) |
IL (1) | IL59065A0 (es) |
NZ (1) | NZ192520A (es) |
ZA (1) | ZA80297B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5284948A (en) * | 1991-06-07 | 1994-02-08 | Eastman Kodak Company | Drug hapten analogues for immunoassays |
ATE204385T1 (de) * | 1991-06-07 | 2001-09-15 | Johnson & Johnson Clin Diag | Immunoassays unter verwendung von markierten hapten-analogen |
US7456429B2 (en) * | 2006-03-29 | 2008-11-25 | Eastman Kodak Company | Apparatus for atomic layer deposition |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2362839A1 (fr) * | 1976-06-03 | 1978-03-24 | Wellcome Found | Derives de l'hydantoine et medicaments contenant ces substances |
IT1143583B (it) * | 1976-06-03 | 1986-10-22 | Wellcome Found | Derivati della idantoina e relativo procedimento di produzione |
GB1602188A (en) * | 1977-12-01 | 1981-11-11 | Wellcome Found | Hydantoin derivatives |
US4152445A (en) * | 1976-12-18 | 1979-05-01 | Beecham Group Limited | 1-(3-Hydroxyalk-1-yl)-5-(carboxyalkyl)hydantoin derivatives |
IE48747B1 (en) * | 1977-09-05 | 1985-05-15 | Wellcome Found | Hydantoin derivatives |
DK543178A (da) * | 1977-12-01 | 1979-06-02 | Wellcome Found | Thiodydantoinderivater |
GB1599740A (en) | 1978-05-31 | 1981-10-07 | Wellcome Found | Hydantoin derivatives |
-
1980
- 1980-01-01 IL IL59065A patent/IL59065A0/xx unknown
- 1980-01-04 NZ NZ192520A patent/NZ192520A/xx unknown
- 1980-01-15 DK DK17380A patent/DK17380A/da not_active Application Discontinuation
- 1980-01-16 US US06/112,693 patent/US4413002A/en not_active Expired - Lifetime
- 1980-01-17 DE DE8080300165T patent/DE3061830D1/de not_active Expired
- 1980-01-17 JP JP405280A patent/JPS55100371A/ja active Pending
- 1980-01-17 ZA ZA00800297A patent/ZA80297B/xx unknown
- 1980-01-17 EP EP80300165A patent/EP0014076B1/en not_active Expired
- 1980-01-18 ES ES487848A patent/ES487848A0/es active Granted
- 1980-01-18 AU AU54720/80A patent/AU5472080A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK17380A (da) | 1981-07-30 |
DE3061830D1 (en) | 1983-03-17 |
EP0014076A3 (en) | 1980-09-17 |
US4413002A (en) | 1983-11-01 |
NZ192520A (en) | 1983-03-15 |
AU5472080A (en) | 1980-07-24 |
EP0014076B1 (en) | 1983-02-09 |
ES487848A0 (es) | 1981-04-16 |
JPS55100371A (en) | 1980-07-31 |
EP0014076A2 (en) | 1980-08-06 |
ZA80297B (en) | 1980-12-31 |
IL59065A0 (en) | 1980-05-30 |
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