ES8103043A1 - Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas - Google Patents
Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinasInfo
- Publication number
- ES8103043A1 ES8103043A1 ES492821A ES492821A ES8103043A1 ES 8103043 A1 ES8103043 A1 ES 8103043A1 ES 492821 A ES492821 A ES 492821A ES 492821 A ES492821 A ES 492821A ES 8103043 A1 ES8103043 A1 ES 8103043A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxymethyl
- alkadien
- piperidines
- trihydroxy
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
OBTENCION DE DERIVADOS DE 2-HIDROXIMETIL-3,4,5-TRIHIDROXIPIPERIDINAS DE FORMULA: *FORMULA* DONDE <N> REPRESENTA UN NUMERO ENTRE 0 Y 5. SE CARACTERIZA PORQUE 1-DESOXIMOJIRIMICINA SE ALQUILA REDUCTIVAMENTE EN PRESENCIA DE UN DONADOR DE H2 CON UN ALDEHIDO DE FORMULA: OCH-(CH=CH(N-H. ESTOS DERIVADOS SE EMPLEAN COMO MEDICAMENTOS, ESPECIALMENTE CONTRA DIABETES, HIPERLIPROTENEMIA, ATEROESCLEROSIS Y ADIPOSITAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792925943 DE2925943A1 (de) | 1979-06-27 | 1979-06-27 | 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
ES492821A0 ES492821A0 (es) | 1981-02-16 |
ES8103043A1 true ES8103043A1 (es) | 1981-02-16 |
Family
ID=6074298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES492821A Expired ES8103043A1 (es) | 1979-06-27 | 1980-06-26 | Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas |
Country Status (16)
Country | Link |
---|---|
US (1) | US4312872A (es) |
EP (1) | EP0022192B1 (es) |
JP (1) | JPS6026388B2 (es) |
AT (1) | ATE3421T1 (es) |
AU (1) | AU5933080A (es) |
CA (1) | CA1138879A (es) |
DE (2) | DE2925943A1 (es) |
DK (1) | DK274980A (es) |
ES (1) | ES8103043A1 (es) |
FI (1) | FI802023A (es) |
GR (1) | GR69296B (es) |
HU (1) | HU180149B (es) |
IL (1) | IL60382A0 (es) |
NO (1) | NO801731L (es) |
PT (1) | PT71408A (es) |
ZA (1) | ZA803818B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56108767A (en) * | 1980-01-28 | 1981-08-28 | Nippon Shinyaku Co Ltd | Bismoranoline derivative |
DE3507019A1 (de) * | 1985-02-28 | 1986-08-28 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung |
US4690486A (en) * | 1985-04-29 | 1987-09-01 | Texas Instruments Incorporated | Four position interlacing apparatus |
US4837026A (en) * | 1985-10-03 | 1989-06-06 | Rajakhyaksha Vithal J | Transdermal and systemic preparation and method |
GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
JPH0369383U (es) * | 1989-11-01 | 1991-07-10 | ||
US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
JP2640897B2 (ja) * | 1992-11-16 | 1997-08-13 | 中央紙器工業株式会社 | 板状材梱包用の段ボール製パッキン |
ATE243196T1 (de) * | 1994-03-09 | 2003-07-15 | Novo Nordisk As | Piperidine und pyrrolidine |
US5863903A (en) * | 1994-03-09 | 1999-01-26 | Novo Nordisk A/S | Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes |
EP0912179B1 (en) * | 1996-07-15 | 2006-04-12 | MacroZyme DNM B.V. | Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
JPS5943946B2 (ja) * | 1978-04-28 | 1984-10-25 | 日本新薬株式会社 | N−アルケニルモラノリン誘導体 |
GB2020278B (en) * | 1978-05-03 | 1983-02-23 | Nippon Shinyaku Co Ltd | Moranoline dervitives |
DE2830469A1 (de) * | 1978-07-11 | 1980-01-24 | Bayer Ag | Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten |
-
1979
- 1979-06-27 DE DE19792925943 patent/DE2925943A1/de not_active Withdrawn
-
1980
- 1980-06-10 NO NO801731A patent/NO801731L/no unknown
- 1980-06-11 US US06/158,541 patent/US4312872A/en not_active Expired - Lifetime
- 1980-06-17 AU AU59330/80A patent/AU5933080A/en not_active Abandoned
- 1980-06-18 AT AT80103367T patent/ATE3421T1/de not_active IP Right Cessation
- 1980-06-18 EP EP80103367A patent/EP0022192B1/de not_active Expired
- 1980-06-18 PT PT71408A patent/PT71408A/pt unknown
- 1980-06-18 DE DE8080103367T patent/DE3063301D1/de not_active Expired
- 1980-06-24 IL IL60382A patent/IL60382A0/xx unknown
- 1980-06-24 JP JP55084672A patent/JPS6026388B2/ja not_active Expired
- 1980-06-25 GR GR62295A patent/GR69296B/el unknown
- 1980-06-25 CA CA000354770A patent/CA1138879A/en not_active Expired
- 1980-06-25 FI FI802023A patent/FI802023A/fi not_active Application Discontinuation
- 1980-06-26 ZA ZA00803818A patent/ZA803818B/xx unknown
- 1980-06-26 DK DK274980A patent/DK274980A/da unknown
- 1980-06-26 ES ES492821A patent/ES8103043A1/es not_active Expired
- 1980-06-26 HU HU80801592A patent/HU180149B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
ES492821A0 (es) | 1981-02-16 |
JPS567763A (en) | 1981-01-27 |
EP0022192B1 (de) | 1983-05-18 |
ATE3421T1 (de) | 1983-06-15 |
DE2925943A1 (de) | 1981-01-29 |
ZA803818B (en) | 1981-07-29 |
JPS6026388B2 (ja) | 1985-06-24 |
CA1138879A (en) | 1983-01-04 |
DE3063301D1 (en) | 1983-07-07 |
PT71408A (de) | 1980-07-01 |
US4312872A (en) | 1982-01-26 |
AU5933080A (en) | 1981-01-08 |
FI802023A (fi) | 1980-12-28 |
HU180149B (en) | 1983-02-28 |
DK274980A (da) | 1980-12-28 |
GR69296B (es) | 1982-05-13 |
IL60382A0 (en) | 1980-09-16 |
NO801731L (no) | 1980-12-29 |
EP0022192A1 (de) | 1981-01-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8402591A1 (es) | Procedimiento para la obtencion de pirazolooxacinas, pirazolotiacinas y pirazoloquinolinas. | |
ES8104228A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridinas op- ticamente activas | |
IL58775A (en) | Hydroxyethyl-azole compounds,their production and pharmaceutical compositions containing them | |
IL58782A0 (en) | Hydroxypropyl-triazole compounds,their production and pharmaceutical compositions containing them | |
ES8103043A1 (es) | Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas | |
DE3064835D1 (en) | 2-hydroxyalkyl-3,4,5,trihydroxy piperidines, processes for their preparation and their use as medicaments | |
ES8200094A1 (es) | Procedimiento para la obtencion de alquilureas | |
ES475633A1 (es) | Procedimiento para la obtencion de derivados de 1-n-4,6-di-0-(aminoglicosil)-1,3-diamino-ciclitol. | |
DE3361990D1 (en) | Alkylene-bridged guanidino-thiazole derivatives, method for their preparation and their use as medicaments | |
ES478048A1 (es) | Procedimiento para la obtencion de difenil-imidazolil-meta- nos sustituidos. | |
ES8103112A1 (es) | Procedimiento para la obtencion de pseudo-trisacaridos | |
ES8305783A1 (es) | Procedimiento para la obtencion de derivados de aminociclitol saturados. | |
ES8200871A1 (es) | Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina | |
IL59295A0 (en) | Dehydropeptide compounds,their production and pharmaceutical compositions containing them | |
IL58774A (en) | Fluorenyl-azolylmethylcarbinol compounds,their production and pharmaceutical compositions containing them | |
ES8306481A1 (es) | Procedimiento para la obtencion de sulfamidas anulares. | |
ES8203843A1 (es) | Procedimiento para la obtencion de amidas de acido 1,4-dihi-dropiridin-4-carboxilico | |
DE3160933D1 (en) | Imidazolyl-indene-thiophenes, process for their preparation and their use as medicaments |