ES543146A0 - Procedimiento para la obtencion de derivados trifenilmetili-cos de la snglicero-3-fosfocolina y sn-glicero-3-fosfoetano-lamina - Google Patents

Procedimiento para la obtencion de derivados trifenilmetili-cos de la snglicero-3-fosfocolina y sn-glicero-3-fosfoetano-lamina

Info

Publication number: ES543146A0
Authority: ES; Spain
Prior art keywords: derivatives; triphenylmethyll; snglicero; fosfoetano; fosfocolina
Prior art date: 1984-05-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES543146A

Other languages

English (en)

Other versions

ES8603899A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Patheon Austria GmbH and Co KG

Original Assignee

Chemie Linz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-15

Filing date

1985-05-14

Publication date

1986-01-01

1985-05-14 Application filed by Chemie Linz AG filed Critical Chemie Linz AG

1986-01-01 Publication of ES543146A0 publication Critical patent/ES543146A0/es

1986-01-01 Publication of ES8603899A1 publication Critical patent/ES8603899A1/es

Status Expired legal-status Critical Current

Links

PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
230000010933 acylation Effects 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
JZNWSCPGTDBMEW-YFKPBYRVSA-N sn-glycero-3-phosphoethanolamine Chemical compound NCCO[P@@](O)(=O)OC[C@@H](O)CO JZNWSCPGTDBMEW-YFKPBYRVSA-N 0.000 abstract 1
125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Epoxy Resins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)

ES543146A 1984-05-15 1985-05-14 Procedimiento para la obtencion de derivados trifenilmetili-cos de la snglicero-3-fosfocolina y sn-glicero-3-fosfoetano-lamina Expired ES8603899A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AT0159084A AT383130B (de)	1984-05-15	1984-05-15	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

Publications (2)

Publication Number	Publication Date
ES543146A0 true ES543146A0 (es)	1986-01-01
ES8603899A1 ES8603899A1 (es)	1986-01-01

Family

ID=3516711

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES543146A Expired ES8603899A1 (es)	1984-05-15	1985-05-14	Procedimiento para la obtencion de derivados trifenilmetili-cos de la snglicero-3-fosfocolina y sn-glicero-3-fosfoetano-lamina
ES543147A Granted ES543147A0 (es)	1984-05-15	1985-05-14	Procedimiento para la obtencion de 1,2-diacil-sn-glicero-3- fosfocolinas y 1,2-diacil-sn-glicero-3-fosfoetanolaminas sustituidas en forma mixta

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES543147A Granted ES543147A0 (es)	1984-05-15	1985-05-14	Procedimiento para la obtencion de 1,2-diacil-sn-glicero-3- fosfocolinas y 1,2-diacil-sn-glicero-3-fosfoetanolaminas sustituidas en forma mixta

Country Status (24)

Country	Link
US (2)	US4622180A (es)
EP (1)	EP0161519B1 (es)
JP (1)	JPS60252490A (es)
KR (1)	KR920009556B1 (es)
CN (1)	CN1014791B (es)
AT (2)	AT383130B (es)
AU (1)	AU565316B2 (es)
BR (1)	BR8502293A (es)
CA (1)	CA1244462A (es)
DD (2)	DD245668A1 (es)
DE (1)	DE3563533D1 (es)
DK (2)	DK167441C (es)
ES (2)	ES8603899A1 (es)
FI (1)	FI77663C (es)
HU (2)	HU203555B (es)
IE (1)	IE58511B1 (es)
IL (1)	IL75133A (es)
NO (1)	NO163100C (es)
NZ (1)	NZ212067A (es)
PH (2)	PH21831A (es)
SU (2)	SU1400511A3 (es)
TR (1)	TR22204A (es)
YU (2)	YU45720B (es)
ZA (1)	ZA853697B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT383130B (de) *	1984-05-15	1987-05-25	Chemie Linz Ag	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin
DE3638687A1 (de) *	1986-11-13	1988-05-19	Lentia Gmbh	Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3-phosphocholinen
AT388165B (de) *	1986-12-10	1989-05-10	Chemie Linz Ag	Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3- phosphocholinen
JP2657486B2 (ja) *	1987-02-20	1997-09-24	花王株式会社	洗浄剤組成物
US5144045A (en) *	1990-11-13	1992-09-01	American Cyanamid Company	Phosphocholine derivative inhibitors of phospholipase A2
US5698537A (en) *	1996-06-18	1997-12-16	Clarion Pharmaceuticals Inc.	Method of lowering the viscosity of mucus
US6838452B2 (en)	2000-11-24	2005-01-04	Vascular Biogenics Ltd.	Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
EP2324828A1 (en) *	2003-08-18	2011-05-25	BTG International Limited	Treatment for neurodegenerative conditions
US7807847B2 (en)	2004-07-09	2010-10-05	Vascular Biogenics Ltd.	Process for the preparation of oxidized phospholipids
GB0425932D0 (en) *	2004-11-25	2004-12-29	Btg Int Ltd	Structured phospholipids
GB0504362D0 (en)	2005-03-02	2005-04-06	Btg Int Ltd	Cytokine modulators
US8569529B2 (en)	2007-01-09	2013-10-29	Vascular Biogenics Ltd.	High-purity phospholipids
US9006217B2 (en)	2007-01-09	2015-04-14	Vascular Biogenics Ltd.	High-purity phospholipids
RU2532546C2 (ru) *	2008-11-06	2014-11-10	Васкьюлар Байодженикс Лтд.	Окисленные соединения липидов и их применение
CN104017019A (zh) *	2014-06-12	2014-09-03	东南大学	一种氮芥-甘油磷脂酰胆碱化合物的合成方法
US9771385B2 (en)	2014-11-26	2017-09-26	Vascular Biogenics Ltd.	Oxidized lipids
WO2016084023A1 (en)	2014-11-26	2016-06-02	Vascular Biogenics Ltd.	Oxidized lipids and treatment or prevention of fibrosis
CZ308596B6 (cs) *	2017-04-03	2020-12-23	Ústav molekulární genetiky AV ČR, v. v. i.	Deriváty fosfolipidů a jejich použití jako léčiva
PL232298B1 (pl) *	2017-06-30	2019-06-28	Univ Przyrodniczy We Wroclawiu	Sposób otrzymywania fosfatydylocholiny zawierającej ibuprofen w pozycji sn-1
PL232663B1 (pl) *	2017-06-30	2019-07-31	Univ Przyrodniczy We Wroclawiu	Fosfatydylocholiny oraz sposób ich otrzymywania

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2820893C2 (de) *	1978-05-12	1986-02-20	A. Nattermann & Cie GmbH, 5000 Köln	Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen
IT1123187B (it) *	1979-09-17	1986-04-30	Lpb Ist Farm	Processo per la preparazione di l-alfa-glicerilfosforilcolina
DE3130867A1 (de) *	1981-08-04	1983-02-24	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Zwischenprodukte zur herstellung von glycerinderivaten
AT383130B (de) *	1984-05-15	1987-05-25	Chemie Linz Ag	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

1984
- 1984-05-15 AT AT0159084A patent/AT383130B/de not_active IP Right Cessation
1985
- 1985-04-19 DE DE8585104662T patent/DE3563533D1/de not_active Expired
- 1985-04-19 AT AT85104662T patent/ATE35416T1/de not_active IP Right Cessation
- 1985-04-19 EP EP85104662A patent/EP0161519B1/de not_active Expired
- 1985-05-07 FI FI851781A patent/FI77663C/fi not_active IP Right Cessation
- 1985-05-07 IE IE113685A patent/IE58511B1/en not_active IP Right Cessation
- 1985-05-08 IL IL75133A patent/IL75133A/xx unknown
- 1985-05-09 CA CA000481204A patent/CA1244462A/en not_active Expired
- 1985-05-13 US US06/733,619 patent/US4622180A/en not_active Expired - Lifetime
- 1985-05-13 PH PH32256A patent/PH21831A/en unknown
- 1985-05-14 NO NO851928A patent/NO163100C/no unknown
- 1985-05-14 KR KR1019850003277A patent/KR920009556B1/ko not_active IP Right Cessation
- 1985-05-14 HU HU895132A patent/HU203555B/hu not_active IP Right Cessation
- 1985-05-14 DD DD85276325A patent/DD245668A1/de not_active IP Right Cessation
- 1985-05-14 DK DK212185A patent/DK167441C/da not_active IP Right Cessation
- 1985-05-14 DD DD85276324A patent/DD233130A1/de not_active IP Right Cessation
- 1985-05-14 ES ES543146A patent/ES8603899A1/es not_active Expired
- 1985-05-14 ES ES543147A patent/ES543147A0/es active Granted
- 1985-05-14 SU SU853896546A patent/SU1400511A3/ru active
- 1985-05-14 HU HU851813A patent/HU199486B/hu not_active IP Right Cessation
- 1985-05-14 SU SU853898601A patent/SU1422999A3/ru active
- 1985-05-14 AU AU42448/85A patent/AU565316B2/en not_active Ceased
- 1985-05-14 NZ NZ212067A patent/NZ212067A/xx unknown
- 1985-05-15 ZA ZA853697A patent/ZA853697B/xx unknown
- 1985-05-15 BR BR8502293A patent/BR8502293A/pt not_active IP Right Cessation
- 1985-05-15 YU YU81685A patent/YU45720B/sh unknown
- 1985-05-15 TR TR22204A patent/TR22204A/xx unknown
- 1985-05-15 JP JP60101644A patent/JPS60252490A/ja active Granted
- 1985-05-15 YU YU81585A patent/YU45719B/sh unknown
- 1985-06-11 CN CN85104463A patent/CN1014791B/zh not_active Expired
1986
- 1986-07-29 US US06/891,515 patent/US4717512A/en not_active Expired - Lifetime
1987
- 1987-07-06 PH PH35499A patent/PH23978A/en unknown
1992
- 1992-08-03 DK DK098192A patent/DK98192A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO163100C (no)	1990-04-04
DK212185A (da)	1985-11-16
ES8603900A1 (es)	1986-01-01
IL75133A0 (en)	1985-09-29
YU45720B (sh)	1992-07-20
EP0161519A3 (en)	1986-02-12
AU565316B2 (en)	1987-09-10
AU4244885A (en)	1985-11-21
YU81585A (en)	1987-10-31
ES8603899A1 (es)	1986-01-01
NO163100B (no)	1989-12-27
DD233130A1 (de)	1986-02-19
YU45719B (sh)	1992-07-20
DK167441B (da)	1993-11-01
CA1251462C (es)	1989-03-21
ZA853697B (en)	1986-01-29
KR920009556B1 (ko)	1992-10-19
CN1014791B (zh)	1991-11-20
HU203555B (en)	1991-08-28
PH23978A (en)	1990-02-09
HU199486B (en)	1990-02-28
AT383130B (de)	1987-05-25
IE58511B1 (en)	1993-10-06
NO851928L (no)	1985-11-18
FI851781A0 (fi)	1985-05-07
PH21831A (en)	1988-03-17
SU1422999A3 (ru)	1988-09-07
DE3563533D1 (en)	1988-08-04
ES543147A0 (es)	1986-01-01
ATE35416T1 (de)	1988-07-15
US4622180A (en)	1986-11-11
NZ212067A (en)	1988-10-28
DK212185D0 (da)	1985-05-14
KR850008677A (ko)	1985-12-21
ATA159084A (de)	1986-10-15
EP0161519B1 (de)	1988-06-29
EP0161519A2 (de)	1985-11-21
TR22204A (tr)	1986-09-24
CN85104463A (zh)	1986-12-10
FI851781L (fi)	1985-11-16
DK98192D0 (da)	1992-08-03
DK98192A (da)	1992-08-03
FI77663C (fi)	1989-04-10
BR8502293A (pt)	1986-01-21
IL75133A (en)	1988-12-30
FI77663B (fi)	1988-12-30
US4717512A (en)	1988-01-05
DD245668A1 (de)	1987-05-13
JPH0482157B2 (es)	1992-12-25
SU1400511A3 (ru)	1988-05-30
HUT39454A (en)	1986-09-29
CA1244462A (en)	1988-11-08
IE851136L (en)	1985-11-15
YU81685A (en)	1987-10-31
JPS60252490A (ja)	1985-12-13
DK167441C (da)	1994-04-18

Legal Events

Date	Code	Title	Description
1997-11-16	FD1A	Patent lapsed	Effective date: 19971001

Publication	Publication Date	Title
ES543146A0 (es)	1986-01-01	Procedimiento para la obtencion de derivados trifenilmetili-cos de la snglicero-3-fosfocolina y sn-glicero-3-fosfoetano-lamina
ES557316A0 (es)	1988-04-01	Procedimiento para la obtencion de derivados de 5-amino-4-hidrovalerilo.
ES552397A0 (es)	1987-05-01	Procedimiento para la obtencion de poli-hidro piridazo diacepinas, triacepinas o diazocinas
ES556369A0 (es)	1988-05-01	Procedimiento para la obtencion de acidos 4-quinolon-3-carboxilicos 1,8- puenteados.
ES543430A0 (es)	1986-01-01	Procedimiento para la obtencion de 1-fenil-3-azabiciclo (3,1,0)hexan-2,4-dionas
ES540173A0 (es)	1985-12-01	Procedimiento para la obtencion de nuevos 1,3,2-dioxaborina-nos
ES541265A0 (es)	1985-12-01	Procedimiento para la obtencion de derivados de tiocianopi- rimidina
ES546557A0 (es)	1987-03-01	Procedimiento para la obtencion de derivados de sulfonilgua-nidinopirimidina
ES555536A0 (es)	1988-01-01	Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno.
ES530125A0 (es)	1985-11-01	Procedimiento para la obtencion de 5-diazacicloalquilimidazo-(i, 2-c)-(i, 3)-benzodiazepinas
ES549906A0 (es)	1987-06-16	Procedimiento para la preparacion de derivados de 1,4-dihi- dropiridina
ES554339A0 (es)	1987-11-16	Procedimiento para la obtencion de derivados de 1,4-dihidropiridina
ES532084A0 (es)	1985-06-16	Procedimiento para la obtencion de derivados de isopropilamino-2-propanol
ES534034A0 (es)	1985-06-16	Procedimiento para la preparacion de derivados del 2, 4-difluorobifenilo
MX157842A (es)	1988-12-16	Procedimiento para la preparacion de 2-oxindoles 1,3 disustituidos
ES530149A0 (es)	1985-04-01	Procedimiento para la obtencion de 2-quinoxalin-metilen-carbazato de metilo-1, 4-dioxido
ES537424A0 (es)	1985-09-16	Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas
ES534861A0 (es)	1986-03-16	Procedimiento para la obtencion de 2,4,6-triyodofenol
ES518495A0 (es)	1984-02-01	Procedimiento para la obtencion de 2-bromometil-2-(2,4-diclorofenil)-4-hidroximetil-1,3-dioxolano.
MX158722A (es)	1989-03-03	Procedimiento para la preparacion de esteres de 3,5-dibromo-4-hi-droxibenzonitrilo