ES541445A0 - Un procedimiento para preparar un sulfato de 5,6,7,8-tetra- hidro-l-eritro-bioptelina - Google Patents
Un procedimiento para preparar un sulfato de 5,6,7,8-tetra- hidro-l-eritro-bioptelinaInfo
- Publication number
- ES541445A0 ES541445A0 ES85541445A ES541445A ES541445A0 ES 541445 A0 ES541445 A0 ES 541445A0 ES 85541445 A ES85541445 A ES 85541445A ES 541445 A ES541445 A ES 541445A ES 541445 A0 ES541445 A0 ES 541445A0
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- biopteline
- eritro
- hydro
- sulphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59056584A JPS60199889A (ja) | 1984-03-24 | 1984-03-24 | 5,6,7,8−テトラヒドロ−l−エリスロ−ビオプテリンの硫酸塩およびその製法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES541445A0 true ES541445A0 (es) | 1986-05-16 |
ES8607255A1 ES8607255A1 (es) | 1986-05-16 |
Family
ID=13031220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES85541445A Expired ES8607255A1 (es) | 1984-03-24 | 1985-03-21 | Un procedimiento para preparar un sulfato de 5,6,7,8-tetra- hidro-l-eritro-bioptelina |
Country Status (7)
Country | Link |
---|---|
US (1) | US4649197A (es) |
EP (1) | EP0156330B1 (es) |
JP (1) | JPS60199889A (es) |
AT (1) | ATE47141T1 (es) |
CA (1) | CA1250837A (es) |
DE (1) | DE3573601D1 (es) |
ES (1) | ES8607255A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0318926B1 (en) * | 1987-11-30 | 1995-05-03 | Kabushiki Kaisha Vitamin Kenkyusyo | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives |
US7442372B2 (en) | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
EP3138566B1 (en) * | 2003-11-17 | 2022-01-26 | BioMarin Pharmaceutical Inc. | Treatment of phenylketonuria with bh4 |
WO2006055511A2 (en) | 2004-11-17 | 2006-05-26 | Biomarin Pharmaceutical Inc. | Stable tablet formulation of tetrahydrobiopterin |
CA2588994A1 (en) * | 2004-12-08 | 2006-06-15 | Biomarin Pharmaceutical Inc. | Methods and compositions for the treatment of pulmonary hypertension of the newborn |
WO2007067570A1 (en) * | 2005-12-05 | 2007-06-14 | Biomarin Pharmaceutical Inc. | Methods and compositions for the treatment of disease |
AU2008206486C1 (en) * | 2007-01-12 | 2013-09-26 | Biomarin Pharmaceutical Inc. | Tetrahydrobiopterin prodrugs |
WO2008089148A1 (en) * | 2007-01-12 | 2008-07-24 | Biomarin Pharmaceutical Inc. | Method of treating a metabolic or neuropsychiatry disorder with a bh4 derivative prodrug |
ES2851177T3 (es) | 2007-04-11 | 2021-09-03 | Biomarin Pharm Inc | Tetrahidrobiopterina para el tratamiento de afecciones asociadas con niveles elevados de fenilalanina |
CA2711160A1 (en) | 2008-01-03 | 2009-07-16 | Biomarin Pharmaceutical Inc. | Pterin analog for treating bh4 responsive condition |
CN101959891A (zh) * | 2008-01-07 | 2011-01-26 | 生物马林药物股份有限公司 | 合成四氢生物蝶呤的方法 |
CN102443006B (zh) | 2010-10-13 | 2016-02-24 | 因华生技制药股份有限公司 | (6r)-四氢生物喋呤盐酸盐的制备方法 |
US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
WO2019175328A1 (en) | 2018-03-14 | 2019-09-19 | Imba - Institut Für Molekulare Biotechnologie Gmbh | Bh4pathwayactivationandusethereoffortreatingcancer |
WO2019175332A1 (en) | 2018-03-14 | 2019-09-19 | Imba - Institut Für Molekulare Biotechnologie Gmbh | Bh4 pathway inhibition and use thereof for treating t-cell mediated autoimmune diseases or hypersensitivity |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA487930A (en) * | 1952-11-11 | Roth Barbara | Salts of substituted pteridines and method of preparing the same | |
US3468886A (en) * | 1967-10-23 | 1969-09-23 | Us Health Education & Welfare | Tetrahydrohomofolic acid sulfate and synthesis thereof |
EP0012444B1 (de) * | 1978-12-18 | 1984-07-25 | Wachter, Helmut, Univ.-Prof. Dr. | Diagnostizierverfahren, insbesondere zur Früherkennung von malignen Tumoren und/oder viralen Erkrankungen und Mittel zu seiner Durchführung |
JPS5883691A (ja) * | 1981-11-13 | 1983-05-19 | Kanegafuchi Chem Ind Co Ltd | 1′,2′−ジアシル−(6r,s)−5,6,7,8−テトラヒドロ−l−ビオプテリンおよびその製法 |
JPS60178887A (ja) * | 1984-02-23 | 1985-09-12 | Kanegafuchi Chem Ind Co Ltd | 5,6,7,8−テトラヒドロ−l−ビオプテリンの製造法 |
-
1984
- 1984-03-24 JP JP59056584A patent/JPS60199889A/ja active Granted
-
1985
- 1985-03-15 CA CA000476629A patent/CA1250837A/en not_active Expired
- 1985-03-18 US US06/712,813 patent/US4649197A/en not_active Expired - Fee Related
- 1985-03-21 ES ES85541445A patent/ES8607255A1/es not_active Expired
- 1985-03-22 EP EP85103417A patent/EP0156330B1/en not_active Expired
- 1985-03-22 AT AT85103417T patent/ATE47141T1/de not_active IP Right Cessation
- 1985-03-22 DE DE8585103417T patent/DE3573601D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CA1250837A (en) | 1989-03-07 |
ATE47141T1 (de) | 1989-10-15 |
JPH0469157B2 (es) | 1992-11-05 |
JPS60199889A (ja) | 1985-10-09 |
EP0156330A2 (en) | 1985-10-02 |
US4649197A (en) | 1987-03-10 |
EP0156330A3 (en) | 1986-10-08 |
ES8607255A1 (es) | 1986-05-16 |
EP0156330B1 (en) | 1989-10-11 |
DE3573601D1 (en) | 1989-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010301 |