ES537944A0 - Procedimiento para la preparacion de (-)-1-(2-fluorofenilo)-2-terciobutilamino-1-etanol. - Google Patents

Procedimiento para la preparacion de (-)-1-(2-fluorofenilo)-2-terciobutilamino-1-etanol.

Info

Publication number: ES537944A0
Authority: ES; Spain
Prior art keywords: fluorophenyl; ethanol; preparation; therzybutylamine; procedure
Prior art date: 1983-11-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES537944A

Other languages

English (en)

Other versions

ES8600207A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cephalon France SAS

Original Assignee

Laboratoire L Lafon SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-15

Filing date

1984-11-15

Publication date

1985-10-01

1984-11-15 Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA

1985-10-01 Publication of ES8600207A1 publication Critical patent/ES8600207A1/es

1985-10-01 Publication of ES537944A0 publication Critical patent/ES537944A0/es

Status Granted legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
-1 2-FLUOROPHENYL Chemical class 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N EtOH Substances CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
XTJMTDZHCLBKFU-UHFFFAOYSA-N 2-(tert-butylamino)-1-(2-fluorophenyl)ethanol Chemical compound CC(C)(C)NCC(O)C1=CC=CC=C1F XTJMTDZHCLBKFU-UHFFFAOYSA-N 0.000 abstract 2
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 2
239000012458 free base Substances 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
230000009466 transformation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES537944A 1983-11-15 1984-11-15 Procedimiento para la preparacion de (-)-1-(2-fluorofenilo)-2-terciobutilamino-1-etanol. Granted ES537944A0 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8318140A FR2554811B2 (fr)	1979-12-14	1983-11-15	(-)-1-(2-fluorophenyl)-2-tertiobutylamino-1-ethanol, utilisation en therapeutique

Publications (2)

Publication Number	Publication Date
ES8600207A1 ES8600207A1 (es)	1985-10-01
ES537944A0 true ES537944A0 (es)	1985-10-01

Family

ID=9294128

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES537944A Granted ES537944A0 (es)	1983-11-15	1984-11-15	Procedimiento para la preparacion de (-)-1-(2-fluorofenilo)-2-terciobutilamino-1-etanol.

Country Status (9)

Country	Link
EP (1)	EP0146443B1 (es)
JP (1)	JPS60126251A (es)
AT (1)	ATE33824T1 (es)
CA (1)	CA1227808A (es)
DE (1)	DE3470735D1 (es)
ES (1)	ES537944A0 (es)
FR (1)	FR2554811B2 (es)
IE (1)	IE58085B1 (es)
ZA (1)	ZA848864B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1043510A (en) *	1963-10-09	1966-09-21	Bayer Ag	D-(--)-n-alkyl-1-phenyl-2-aminoethanols
DE1493941A1 (de) *	1964-12-04	1969-03-06	Selvi & C Lab Bioterapico	Verfahren zur Herstellung der linksdrehenden Form des 1-(4'-nitrophenyl)-2-isopropylamin-aethanol und seiner Salze
DE3165495D1 (en) *	1981-03-23	1984-09-20	Lafon Labor	Derivatives of fluorophenacyl amines and their therapeutic use
JPS57169450A (en) *	1981-04-13	1982-10-19	Lafon Labor	Fluorophenacyl-amine derivative and application to remedy

1983
- 1983-11-15 FR FR8318140A patent/FR2554811B2/fr not_active Expired
1984
- 1984-11-12 IE IE290284A patent/IE58085B1/en not_active IP Right Cessation
- 1984-11-13 CA CA000467625A patent/CA1227808A/en not_active Expired
- 1984-11-14 AT AT84402313T patent/ATE33824T1/de not_active IP Right Cessation
- 1984-11-14 ZA ZA848864A patent/ZA848864B/xx unknown
- 1984-11-14 EP EP84402313A patent/EP0146443B1/fr not_active Expired
- 1984-11-14 DE DE8484402313T patent/DE3470735D1/de not_active Expired
- 1984-11-15 JP JP59241550A patent/JPS60126251A/ja active Pending
- 1984-11-15 ES ES537944A patent/ES537944A0/es active Granted

Also Published As

Publication number	Publication date
FR2554811B2 (fr)	1987-02-13
IE58085B1 (en)	1993-06-30
EP0146443B1 (fr)	1988-04-27
ES8600207A1 (es)	1985-10-01
JPS60126251A (ja)	1985-07-05
ZA848864B (en)	1985-07-31
FR2554811A2 (fr)	1985-05-17
EP0146443A1 (fr)	1985-06-26
ATE33824T1 (de)	1988-05-15
IE842902L (en)	1985-05-15
DE3470735D1 (en)	1988-06-01
CA1227808A (en)	1987-10-06

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Legal Events

Date	Code	Title	Description
2000-07-01	FD1A	Patent lapsed	Effective date: 20000503