ES516357A0 - "procedimiento para preparar 1-(3-(6-fluor-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas". - Google Patents

"procedimiento para preparar 1-(3-(6-fluor-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas".

Info

Publication number
ES516357A0
ES516357A0 ES516357A ES516357A ES516357A0 ES 516357 A0 ES516357 A0 ES 516357A0 ES 516357 A ES516357 A ES 516357A ES 516357 A ES516357 A ES 516357A ES 516357 A0 ES516357 A0 ES 516357A0
Authority
ES
Spain
Prior art keywords
hydroxipiperidines
propil
benzisoxazol
fluor
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES516357A
Other languages
English (en)
Other versions
ES8400745A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES516357A0 publication Critical patent/ES516357A0/es
Publication of ES8400745A1 publication Critical patent/ES8400745A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES516357A 1982-04-09 1982-10-08 "procedimiento para preparar 1-(3-(6-fluor-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas". Expired ES8400745A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/366,247 US4396770A (en) 1982-04-09 1982-04-09 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines

Publications (2)

Publication Number Publication Date
ES516357A0 true ES516357A0 (es) 1983-11-01
ES8400745A1 ES8400745A1 (es) 1983-11-01

Family

ID=23442253

Family Applications (2)

Application Number Title Priority Date Filing Date
ES516357A Expired ES8400745A1 (es) 1982-04-09 1982-10-08 "procedimiento para preparar 1-(3-(6-fluor-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas".
ES517763A Granted ES517763A0 (es) 1982-04-09 1982-11-29 Procedimiento para preparar 1-(3-(6-fluoro-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES517763A Granted ES517763A0 (es) 1982-04-09 1982-11-29 Procedimiento para preparar 1-(3-(6-fluoro-1,2-benzisoxazol-3-il)propil)-4-fenil-4-hidroxipiperidinas.

Country Status (6)

Country Link
US (1) US4396770A (es)
JP (1) JPS58177989A (es)
CA (1) CA1197510A (es)
ES (2) ES8400745A1 (es)
HU (1) HU191086B (es)
PH (1) PH18982A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835177A (ja) * 1981-08-26 1983-03-01 Dainippon Pharmaceut Co Ltd ２−環状アミノ−２−（１，２−ベンズイソキサゾ−ル−３−イル）酢酸エステル類並びにその酸付加塩類および第４級アンモニウム塩類
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4609658A (en) * 1982-04-09 1986-09-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4610988A (en) * 1982-04-09 1986-09-09 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
US4980365A (en) * 1987-07-13 1990-12-25 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
BR9205811A (pt) * 1991-03-28 1994-06-28 Pfizer Derivados heterociclicos de aminas ciclicas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1488003A (en) * 1973-10-23 1977-10-05 Lilly Industries Ltd 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals
FI60390C (fi) * 1975-03-05 1982-01-11 Sumitomo Chemical Co Foerfarande foer framstaellning av neuroleptiska butyrofenoner

Also Published As

Publication number Publication date
PH18982A (en) 1985-11-29
HU191086B (en) 1987-01-28
ES8401484A1 (es) 1983-12-16
CA1197510A (en) 1985-12-03
US4396770A (en) 1983-08-02
ES517763A0 (es) 1983-12-16
JPS58177989A (ja) 1983-10-18
ES8400745A1 (es) 1983-11-01

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