ES494590A0 - Procedimiento para la preparacion de derivados de acidos b- carbolin-3-carboxilicos - Google Patents

Procedimiento para la preparacion de derivados de acidos b- carbolin-3-carboxilicos

Info

Publication number
ES494590A0
ES494590A0 ES494590A ES494590A ES494590A0 ES 494590 A0 ES494590 A0 ES 494590A0 ES 494590 A ES494590 A ES 494590A ES 494590 A ES494590 A ES 494590A ES 494590 A0 ES494590 A0 ES 494590A0
Authority
ES
Spain
Prior art keywords
carbolin
procedure
preparation
acid derivatives
carboxyl acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES494590A
Other languages
English (en)
Other versions
ES8106305A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK88980A external-priority patent/DK88980A/da
Priority claimed from DE19803015816 external-priority patent/DE3015816A1/de
Priority claimed from DE19803023567 external-priority patent/DE3023567A1/de
Application filed by Schering AG filed Critical Schering AG
Publication of ES494590A0 publication Critical patent/ES494590A0/es
Publication of ES8106305A1 publication Critical patent/ES8106305A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES494590A 1979-08-29 1980-08-29 Procedimiento para la preparacion de derivados de acidos b- carbolin-3-carboxilicos Expired ES8106305A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK362279 1979-08-29
DK88980A DK88980A (da) 1980-02-29 1980-02-29 Beta-carbonline-3-carboxylsyrederivater og fremgangsmaader til fremstilling af samme
DE19803015816 DE3015816A1 (de) 1980-04-22 1980-04-22 4-substituierte- (beta) -carbolin-3-carbonsaeurederivate, ihre herstellung und verwendung
DE19803023567 DE3023567A1 (de) 1980-06-20 1980-06-20 Substituierte (beta) -carbolin-3-carbonsaeurederivate

Publications (2)

Publication Number Publication Date
ES494590A0 true ES494590A0 (es) 1981-08-16
ES8106305A1 ES8106305A1 (es) 1981-08-16

Family

ID=27432526

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494590A Expired ES8106305A1 (es) 1979-08-29 1980-08-29 Procedimiento para la preparacion de derivados de acidos b- carbolin-3-carboxilicos

Country Status (16)

Country Link
US (2) US4371536A (es)
EP (1) EP0030254B1 (es)
CA (1) CA1150246A (es)
DD (1) DD152935A5 (es)
DE (1) DE3069559D1 (es)
ES (1) ES8106305A1 (es)
FI (1) FI68829C (es)
HU (1) HU186744B (es)
IE (1) IE50229B1 (es)
IL (1) IL60906A (es)
NO (1) NO155055C (es)
NZ (1) NZ194747A (es)
PL (1) PL226479A1 (es)
PT (1) PT71744B (es)
RO (1) RO80265B (es)
YU (1) YU215580A (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DK149270C (da) * 1983-05-27 1986-08-25 Schering Ag Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater
DE3322894A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DE3335323A1 (de) 1983-09-27 1985-04-04 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
FR2555988A1 (fr) * 1983-12-06 1985-06-07 Centre Nat Rech Scient Derive de b-carbolines, procede pour leurs preparations et medicament les contenant
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DE3535928A1 (de) * 1985-10-04 1987-04-09 Schering Ag Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
EP0285671B1 (en) * 1986-10-13 2003-09-03 Asahi Kasei Kabushiki Kaisha Pyridine derivatives
DE4029389A1 (de) * 1990-09-13 1992-03-26 Schering Ag Verfahren zur herstellung von (beta)-carbolin-derivaten
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
GB9508195D0 (en) * 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
ES2169857T3 (es) * 1996-04-04 2002-07-16 Hoffmann La Roche Uso de derivados de tetrahidro-beta-carbolinas como agentes antimetastaticos.
ES2194213T3 (es) * 1996-08-09 2003-11-16 Boehringer Ingelheim Pharma Beta-carbolinas-4- sustituidas en calidad de inmunomoduladores.
UA74826C2 (en) 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
AR036040A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
IL160884A0 (en) 2001-10-02 2004-08-31 Upjohn Co Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
BR0214016A (pt) 2001-11-09 2004-10-13 Upjohn Co Compostos azabicìclico-fenil-fundido heterocìclicos e seu uso como ligandos alfa 7 nachr
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
JP2005523288A (ja) 2002-02-19 2005-08-04 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 疾病治療用の縮合した二環式−ｎ−架橋−複素環式芳香族カルボキサミド
PA8586801A1 (es) * 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
BRPI0407052A (pt) * 2003-01-27 2006-01-17 Pfizer Inibidores da hiv-integrase, composições farmacêuticas, e métodos para sua utilização
CN100503607C (zh) 2003-06-02 2009-06-24 新疆华世丹药物研究有限责任公司 去氢骆驼蓬碱衍生物类化合物及其应用
CA2563761C (en) * 2004-04-26 2009-12-29 Pfizer Inc. Inhibitors of the hiv integrase enzyme
WO2005103003A2 (en) 2004-04-26 2005-11-03 Pfizer Inc. Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors
RS20080141A (en) * 2005-10-07 2009-07-15 Pfizer Products Inc., Inhibitors of the hiv integrase enzyme
CN101573333B (zh) 2006-10-28 2013-06-12 梅特希尔基因公司 组蛋白脱乙酰酶抑制剂
AU2013205135B2 (en) * 2006-10-28 2015-11-05 Forum Pharmaceuticals Inc. Inhibitors of histone deacetylase
US8268854B2 (en) 2008-05-22 2012-09-18 The Uwm Research Foundation, Inc. Aza-beta-carbolines and methods of using same
CN104211699A (zh) * 2013-06-05 2014-12-17 首都医科大学 β-咔啉衍生物,其制备,纳米结构,抗肿瘤活性和应用
CN104628722B (zh) * 2015-01-30 2016-06-22 华南农业大学 一种骆驼蓬碱酰胺类化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA786351A (en) * 1968-05-28 Leonard Frederick PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLIN-CARBOXYLIC ACID AMIDE DERIVATIVES
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
GB1084257A (es) * 1963-11-06
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3322894A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung

Also Published As

Publication number Publication date
IL60906A (en) 1985-11-29
IE801806L (en) 1981-02-28
NZ194747A (en) 1988-11-29
FI68829C (fi) 1985-11-11
RO80265B (ro) 1983-04-30
YU215580A (en) 1984-02-29
IL60906A0 (en) 1980-10-26
NO802546L (no) 1981-03-02
PT71744B (en) 1981-06-08
EP0030254A1 (en) 1981-06-17
NO155055B (no) 1986-10-27
PL226479A1 (es) 1981-10-30
DE3069559D1 (en) 1984-12-06
RO80265A (ro) 1983-04-29
HU186744B (en) 1985-09-30
DD152935A5 (de) 1981-12-16
FI68829B (fi) 1985-07-31
US5010077A (en) 1991-04-23
NO155055C (no) 1987-02-04
IE50229B1 (en) 1986-03-05
FI802720A (fi) 1981-03-01
US4371536A (en) 1983-02-01
PT71744A (en) 1980-09-01
ES8106305A1 (es) 1981-08-16
CA1150246A (en) 1983-07-19
EP0030254B1 (en) 1984-10-31

Similar Documents

Publication Publication Date Title
ES494590A0 (es) Procedimiento para la preparacion de derivados de acidos b- carbolin-3-carboxilicos
ES489934A0 (es) Procedimiento para la preparacion de derivados de pipreridi-na
ES490536A0 (es) Procedimiento para la preparacion de derivados de la glici- namida
MX6749E (es) Procedimiento para la preparacion de derivados de tetrazolilalcoxicarboestirilo
ES492891A0 (es) Procedimiento para la preparacion de derivados triyodados deacido 5-amino- isoftalico
AR227645A1 (es) Procedimiento para la preparacion de oxoalcohilxantinas
ES494989A0 (es) Procedimiento para la preparacion de derivados de aminoaci- dos
ES492566A0 (es) Procedimiento para la preparacion de nuevos derivados de en-cafalina
ES495977A0 (es) Un procedimiento para la preparacion de derivados acidos penem-carboxilicos
AR221428A1 (es) Procedimiento para la preparacion de derivados de pirrolidinil-y de pirrolidinilmetil-benzamidas
ES491143A0 (es) Procedimiento para la preparacion de derivados de bencimida-zol
ES496382A0 (es) Procedimiento para la preparacion de acidos oxocarboxilicos sustituidos
ES491154A0 (es) Procedimiento para la preparacion de derivados furanonicos
MX6221E (es) Procedimiento para la preparacion de derivados de homoserina
MX5594E (es) Procedimiento mejorado para la preparacion de derivados de n-trifluoroacetil-n-fosfonometilglicinatos
AR225159A1 (es) Procedimiento para la preparacion de l-alpha-gliceril-fosforilcolina
ES491601A0 (es) Procedimiento para la preparacion de derivados de acido n-acil-amino
ES494594A0 (es) Procedimiento para la preparacion de derivados de acidos al-canocarboxilicos
ES490959A0 (es) Procedimiento para la preparacion de derivados de acidos pi-rrolidinilsulfamoilbenzoicos sustituidos
MX5955E (es) Procedimiento para la preparacion de derivados de piridoxina
AR224518A1 (es) Procedimiento para la preparacion de derivados de 1-piperidino-ftalazina
MX5674E (es) Procedimiento para la preparacion de derivados de la butenofenona
MX5445E (es) Procedimiento para la preparacion de derivados de isotiocianobenzotiazol
AR223383A1 (es) Procedimiento para la preparacion de 2-isopropilamino-pirimidina
ES494222A0 (es) Procedimiento para la preparacion de derivados de cinamoil- piperidinobutirofenona

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301