ES485441A1 - Un procedimiento para la preparacion de antibioticos de ce- falosporina - Google Patents
Un procedimiento para la preparacion de antibioticos de ce- falosporinaInfo
- Publication number
- ES485441A1 ES485441A1 ES485441A ES485441A ES485441A1 ES 485441 A1 ES485441 A1 ES 485441A1 ES 485441 A ES485441 A ES 485441A ES 485441 A ES485441 A ES 485441A ES 485441 A1 ES485441 A1 ES 485441A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotics
- alkyl group
- activity against
- high activity
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- -1 Cephalosporin compounds Chemical class 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 3
- 229940088710 antibiotic agent Drugs 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 241000588921 Enterobacteriaceae Species 0.000 abstract 1
- 241000589516 Pseudomonas Species 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para la preparación de antibióticos de cefalosporina de la fórmula general **(Fórmula)** (donde Ra y Rb, que pueden ser iguales o diferentes, representan cada una de ellas un grupo alcohilo de 1 a 4 átomós de carbono, o Ra y Rb, junto con el átomo de carbono al cual están unidos, forman un grupo cicloalcohilideno de 3 a 7 átomos de carbono; y R1 representa un grupo alcohilo de 1 a 4 átomos de carbono) y sales no tóxicas y ésteres no tóxicos y metabólicamente lábiles de los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7842165 | 1978-10-27 | ||
| GB7842164 | 1978-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES485441A1 true ES485441A1 (es) | 1980-07-01 |
Family
ID=26269350
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES485441A Expired ES485441A1 (es) | 1978-10-27 | 1979-10-26 | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
| ES485439A Expired ES485439A1 (es) | 1978-10-27 | 1979-10-26 | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
| ES485440A Expired ES485440A1 (es) | 1978-10-27 | 1979-10-26 | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES485439A Expired ES485439A1 (es) | 1978-10-27 | 1979-10-26 | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
| ES485440A Expired ES485440A1 (es) | 1978-10-27 | 1979-10-26 | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT369009B (es) |
| CA (1) | CA1130280A (es) |
| CH (1) | CH644868A5 (es) |
| DE (1) | DE2943427A1 (es) |
| DK (1) | DK452679A (es) |
| ES (3) | ES485441A1 (es) |
| FR (1) | FR2439786A1 (es) |
| GB (1) | GB2036724B (es) |
| IE (1) | IE49100B1 (es) |
| IT (1) | IT1126819B (es) |
| NL (1) | NL7907882A (es) |
| NZ (1) | NZ191937A (es) |
| SE (1) | SE7908896L (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR78245B (es) * | 1980-09-12 | 1984-09-26 | Ciba Geigy Ag | |
| KR860000487B1 (ko) * | 1980-09-25 | 1986-04-30 | 도야마 가가꾸 고오교 가부시끼가이샤 | 세팔로스포린의 제조방법 |
| NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
| EP0062321B1 (en) * | 1981-04-03 | 1989-03-01 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
| FR2533216A1 (fr) * | 1982-09-22 | 1984-03-23 | Toyama Chemical Co Ltd | Nouvelles cephalosporines, et leurs sels |
| DE3336757A1 (de) * | 1983-10-08 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| CA1299564C (en) * | 1985-09-03 | 1992-04-28 | Akihiro Shimabayashi | Cephalosporin derivative |
| US4826834A (en) * | 1985-09-27 | 1989-05-02 | Takeda Chemical Industries, Ltd. | Cephem compounds |
| CN86107947A (zh) * | 1985-11-22 | 1987-05-27 | 藤沢药品工业株式会社 | 新的头孢烯化合物及其制备方法 |
| KR930009796B1 (ko) * | 1991-05-25 | 1993-10-11 | 주식회사 대웅제약 | 신규의 세팔로스포린 및 그의 제조방법 |
| CN114105903B (zh) * | 2021-12-16 | 2023-06-27 | 河北合佳医药科技集团股份有限公司 | 一种高纯度去甲基氨噻肟酸乙酯的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE42144B1 (en) * | 1973-12-21 | 1980-06-18 | Glaxo Lab Ltd | Improvements in or relating to antibiotics |
| GB1496757A (en) * | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
| NO750810L (es) * | 1974-03-20 | 1975-09-23 | Hoeganaes Ab | |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
-
1979
- 1979-10-26 ES ES485441A patent/ES485441A1/es not_active Expired
- 1979-10-26 IT IT50680/79A patent/IT1126819B/it active
- 1979-10-26 ES ES485439A patent/ES485439A1/es not_active Expired
- 1979-10-26 DE DE19792943427 patent/DE2943427A1/de not_active Withdrawn
- 1979-10-26 CA CA338,576A patent/CA1130280A/en not_active Expired
- 1979-10-26 CH CH964579A patent/CH644868A5/de not_active IP Right Cessation
- 1979-10-26 SE SE7908896A patent/SE7908896L/xx not_active Application Discontinuation
- 1979-10-26 FR FR7926634A patent/FR2439786A1/fr active Granted
- 1979-10-26 ES ES485440A patent/ES485440A1/es not_active Expired
- 1979-10-26 DK DK452679A patent/DK452679A/da not_active Application Discontinuation
- 1979-10-26 IE IE2070/79A patent/IE49100B1/en unknown
- 1979-10-26 NL NL7907882A patent/NL7907882A/nl not_active Application Discontinuation
- 1979-10-26 NZ NZ191937A patent/NZ191937A/xx unknown
- 1979-10-26 GB GB7937305A patent/GB2036724B/en not_active Expired
- 1979-10-29 AT AT0698079A patent/AT369009B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE792070L (en) | 1980-04-27 |
| GB2036724A (en) | 1980-07-02 |
| IE49100B1 (en) | 1985-07-24 |
| AT369009B (de) | 1982-11-25 |
| IT7950680A0 (it) | 1979-10-26 |
| CH644868A5 (de) | 1984-08-31 |
| FR2439786A1 (fr) | 1980-05-23 |
| DE2943427A1 (de) | 1980-05-08 |
| DK452679A (da) | 1980-04-28 |
| ATA698079A (de) | 1982-04-15 |
| NZ191937A (en) | 1982-09-07 |
| ES485439A1 (es) | 1980-07-01 |
| GB2036724B (en) | 1983-01-19 |
| FR2439786B1 (es) | 1983-05-20 |
| SE7908896L (sv) | 1980-04-28 |
| NL7907882A (nl) | 1980-04-29 |
| IT1126819B (it) | 1986-05-21 |
| ES485440A1 (es) | 1980-07-01 |
| CA1130280A (en) | 1982-08-24 |
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