ES484056A1 - Un procedimiento para la preparacion de un derivado de glio-xal-2-oxima - Google Patents
Un procedimiento para la preparacion de un derivado de glio-xal-2-oximaInfo
- Publication number
- ES484056A1 ES484056A1 ES484056A ES484056A ES484056A1 ES 484056 A1 ES484056 A1 ES 484056A1 ES 484056 A ES484056 A ES 484056A ES 484056 A ES484056 A ES 484056A ES 484056 A1 ES484056 A1 ES 484056A1
- Authority
- ES
- Spain
- Prior art keywords
- glyoxal
- derivatives
- relieving pain
- oxim
- inflammation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- GSIPOZWLYGLXDM-UHFFFAOYSA-N 1,2-oxazole-5-carbaldehyde Chemical compound O=CC1=CC=NO1 GSIPOZWLYGLXDM-UHFFFAOYSA-N 0.000 abstract 1
- GKUBGXGRJNAABQ-UHFFFAOYSA-N 1-(1,2-oxazol-5-yl)ethanone Chemical compound CC(=O)C1=CC=NO1 GKUBGXGRJNAABQ-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract 1
- 150000004703 alkoxides Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- LYGJENNIWJXYER-UHFFFAOYSA-N nitromethane Chemical compound C[N+]([O-])=O LYGJENNIWJXYER-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Un procedimiento para la preparación de un derivado de glioxal-2-oxima representado por la fórmula: **(fórmula-01)** (I) donde R es hidrógeno o un grupo alquilo inferior C{sub, 1-4} o fenilo, cuyo procedimiento consiste en hacer reaccionar un compuesto de fórmula: **(fórmula-02)** (III) donde R es el definido anteriormente, con un conpuesto de fórmula R''ONO (IV) donde R'' es hidrógeno o un grupo alquilo inferior C{sub, 1-4}, a una temperatura de -10ºC a 50ºC.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP53027300A JPS6034546B2 (ja) | 1978-03-09 | 1978-03-09 | グリオキサ−ル−２−オキシム誘導体及びその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484056A1 true ES484056A1 (es) | 1980-04-16 |
Family
ID=12217231
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478416A Expired ES478416A1 (es) | 1978-03-09 | 1979-03-08 | Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima. |
| ES484056A Expired ES484056A1 (es) | 1978-03-09 | 1979-09-10 | Un procedimiento para la preparacion de un derivado de glio-xal-2-oxima |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478416A Expired ES478416A1 (es) | 1978-03-09 | 1979-03-08 | Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima. |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US4212874A (es) |
| JP (1) | JPS6034546B2 (es) |
| DE (1) | DE2909025A1 (es) |
| ES (2) | ES478416A1 (es) |
| FR (1) | FR2419289A1 (es) |
| GB (1) | GB2017091B (es) |
| IT (1) | IT1114569B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6139453U (ja) * | 1984-08-17 | 1986-03-12 | 三菱自動車工業株式会社 | 電子ビ−ム溶接ピストン |
| DE3528753A1 (de) * | 1985-08-10 | 1987-02-19 | Bayer Ag | Substituierte pyrazolin-5-one |
| DE3726127A1 (de) * | 1987-08-06 | 1989-02-16 | Basf Ag | 5-formylisoxazole |
| DE3738909A1 (de) * | 1987-11-17 | 1989-05-24 | Basf Ag | Verfahren zur herstellung von heterocyclisch-aromatischen aldehyden |
| US5360811A (en) * | 1990-03-13 | 1994-11-01 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents |
| US7229359B2 (en) * | 2003-10-24 | 2007-06-12 | Henry, Schooley & Associates, L.L.C. | Continuous water ride |
| CA2611139A1 (en) * | 2005-04-20 | 2006-10-26 | Henry, Schooley & Associates, L.L.C. | Water amusement system with composite trees |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2772280A (en) * | 1954-12-23 | 1956-11-27 | Merck & Co Inc | Synthesis of 4-amino-3-isoxazolidone and its derivatives |
| SE307356B (es) * | 1963-07-31 | 1969-01-07 | Shionogi & Co | |
| GB1101158A (en) * | 1964-11-20 | 1968-01-31 | Shionogi & Co | Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives |
| GB1164510A (en) * | 1967-06-15 | 1969-09-17 | Ici Ltd | Novel Isoxazole Derivatives, the preparation thereof, and Compositions containing the same |
| FR2073284B1 (es) * | 1969-12-23 | 1973-07-13 | Ferlux | |
| JPS5229311B2 (es) * | 1972-08-22 | 1977-08-01 |
-
1978
- 1978-03-09 JP JP53027300A patent/JPS6034546B2/ja not_active Expired
-
1979
- 1979-03-02 US US05/016,821 patent/US4212874A/en not_active Expired - Lifetime
- 1979-03-07 IT IT48245/79A patent/IT1114569B/it active
- 1979-03-08 FR FR7905980A patent/FR2419289A1/fr active Granted
- 1979-03-08 GB GB7908203A patent/GB2017091B/en not_active Expired
- 1979-03-08 DE DE19792909025 patent/DE2909025A1/de not_active Withdrawn
- 1979-03-08 ES ES478416A patent/ES478416A1/es not_active Expired
- 1979-08-20 US US06/067,889 patent/US4243812A/en not_active Expired - Lifetime
- 1979-08-20 US US06/067,888 patent/US4224450A/en not_active Expired - Lifetime
- 1979-09-10 ES ES484056A patent/ES484056A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES478416A1 (es) | 1979-12-16 |
| US4224450A (en) | 1980-09-23 |
| GB2017091B (en) | 1982-09-02 |
| IT7948245A0 (it) | 1979-03-07 |
| IT1114569B (it) | 1986-01-27 |
| US4212874A (en) | 1980-07-15 |
| FR2419289A1 (fr) | 1979-10-05 |
| FR2419289B1 (es) | 1982-10-08 |
| DE2909025A1 (de) | 1979-09-13 |
| JPS54119457A (en) | 1979-09-17 |
| JPS6034546B2 (ja) | 1985-08-09 |
| GB2017091A (en) | 1979-10-03 |
| US4243812A (en) | 1981-01-06 |
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