ES482742A1 - Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2)sustituidas - Google Patents

Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2)sustituidas

Info

Publication number
ES482742A1
ES482742A1 ES482742A ES482742A ES482742A1 ES 482742 A1 ES482742 A1 ES 482742A1 ES 482742 A ES482742 A ES 482742A ES 482742 A ES482742 A ES 482742A ES 482742 A1 ES482742 A1 ES 482742A1
Authority
ES
Spain
Prior art keywords
imidazolines
phenylamino
substituted
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482742A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES482742A1 publication Critical patent/ES482742A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de 2-fenil- amino-imidazolinas-(2) sustituidas de la fórmula general **(Fórmula)** en que Ar significa los radicales 2,6-dibromofenilo, 2-fluoro-6- trifluorometilfenilo, 2-fluoro-6-clorofenilo, 2- cloro-6-bromofenilo, 2,6-difluorofenilo, 2,4- diclorofenilo, 2-bromo-3-clorofenilo, 2,6 dicloro- 4-hidroxicarbonil-fenilo, 2,6-dicloro-4- etoxicarbonil-fenilo, 2,6-dicloro-4-metoxi-fenilo o 2 bromo-6-fluorofenilo, así como sus sales por adición de ácido.
ES482742A 1978-07-22 1979-07-21 Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2)sustituidas Expired ES482742A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782832310 DE2832310A1 (de) 1978-07-22 1978-07-22 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
ES482742A1 true ES482742A1 (es) 1980-04-16

Family

ID=6045138

Family Applications (1)

Application Number Title Priority Date Filing Date
ES482742A Expired ES482742A1 (es) 1978-07-22 1979-07-21 Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2)sustituidas

Country Status (13)

Country Link
EP (1) EP0007991A1 (es)
JP (1) JPS5519272A (es)
AU (1) AU4910179A (es)
DE (1) DE2832310A1 (es)
DK (1) DK307079A (es)
ES (1) ES482742A1 (es)
FI (1) FI792275A (es)
GR (1) GR69649B (es)
IL (1) IL57854A0 (es)
NO (1) NO792406L (es)
NZ (1) NZ191067A (es)
PT (1) PT69952A (es)
ZA (1) ZA793720B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US7049326B2 (en) 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects
US6750238B1 (en) * 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759125A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-allyl-2-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
DE2523103C3 (de) * 1975-05-24 1979-11-29 C.H. Boehringer Sohn, 6507 Ingelheim Substituierte 2-[N-Progargyl-N-(2-chlorphenyl)amino] -imidazoline-^), deren Säureadditionssalze, Verfahren zu ihrer Herstellung und deren Verwendung

Also Published As

Publication number Publication date
DE2832310A1 (de) 1980-02-07
ZA793720B (en) 1981-03-25
PT69952A (de) 1979-08-01
FI792275A (fi) 1980-01-23
DK307079A (da) 1980-01-23
JPS5519272A (en) 1980-02-09
NZ191067A (en) 1981-05-01
EP0007991A1 (de) 1980-02-20
AU4910179A (en) 1980-01-31
NO792406L (no) 1980-01-23
GR69649B (es) 1982-07-07
IL57854A0 (en) 1979-11-30

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