ES482112A1 - Procedimiento de preparacion de nuevos derivados de 3,20- dioxo-4,9-dieno-21-hidroxilo-esteroides. - Google Patents

Procedimiento de preparacion de nuevos derivados de 3,20- dioxo-4,9-dieno-21-hidroxilo-esteroides.

Info

Publication number
ES482112A1
ES482112A1 ES482112A ES482112A ES482112A1 ES 482112 A1 ES482112 A1 ES 482112A1 ES 482112 A ES482112 A ES 482112A ES 482112 A ES482112 A ES 482112A ES 482112 A1 ES482112 A1 ES 482112A1
Authority
ES
Spain
Prior art keywords
preparation
dioxo
diene
medicines
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482112A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES482112A1 publication Critical patent/ES482112A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Procedimiento de preparación de nuevos derivados de 3,20- dioxo-4,9-dieno-21-hidroxilo-esteroides de fórmula I: **(Fórmula)** en la que: X representa un átomo de hidrógeno o un átomo de tritio, R1 representa un radical alcohilo que contiene de 1 a 3 átomos de carbono, R2 un alcohilo que contiene de 1 a 12 átomos de carbono, R3 un radical alcohilo que contiene de 1 a 4 átomos de carbono, en forma de cada uno de los epímeros 21R ó 21S, o en forma de una mezcla de estos epímeros.
ES482112A 1978-07-13 1979-07-02 Procedimiento de preparacion de nuevos derivados de 3,20- dioxo-4,9-dieno-21-hidroxilo-esteroides. Expired ES482112A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7820973A FR2430953A1 (fr) 1978-07-13 1978-07-13 Nouveaux derives 3,20-dioxo 4,9-diene 21-hydroxyle, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES482112A1 true ES482112A1 (es) 1980-07-01

Family

ID=9210732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES482112A Expired ES482112A1 (es) 1978-07-13 1979-07-02 Procedimiento de preparacion de nuevos derivados de 3,20- dioxo-4,9-dieno-21-hidroxilo-esteroides.

Country Status (15)

Country Link
US (1) US4273771A (es)
EP (2) EP0007823B1 (es)
JP (2) JPS5515475A (es)
AT (1) ATE8899T1 (es)
AU (1) AU527592B2 (es)
CA (1) CA1131215A (es)
DE (1) DE2965904D1 (es)
DK (2) DK163361C (es)
ES (1) ES482112A1 (es)
FR (1) FR2430953A1 (es)
HU (1) HU178088B (es)
IE (1) IE49457B1 (es)
IL (1) IL57691A (es)
PT (1) PT69903A (es)
ZA (1) ZA793453B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5830145A (ja) * 1981-08-17 1983-02-22 Sony Corp 半導体装置の製造方法
FR2549067B1 (fr) * 1983-06-14 1985-12-27 Roussel Uclaf Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques
US4804541A (en) * 1987-08-11 1989-02-14 Moleculon, Inc. Transdermal administration using benzyl alcohol
US5516790A (en) * 1989-01-23 1996-05-14 Texas A&M University System Technology Licensing Office Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents
FR2692267B1 (fr) * 1992-06-11 1995-05-19 Roussel Uclaf Nouveau procédé de préparation de composés stéroïdes 20-céto 21alpha-hydroxy et intermédiaires.
FR2694007B1 (fr) * 1992-07-23 1994-09-30 Roussel Uclaf Nouveau procédé de préparation de composés stéroïdes 20-céto 21 (S) hydroxy et des intermédiaires.
FR2749012B1 (fr) * 1996-05-22 1998-08-07 Hoechst Marion Roussel Inc Nouveaux steroides 1 ou 6-hydroxyles, leur procede de preparation, leur application a titre de medicament et les compositions pharmaceutiques les renfermant
FR2749514B1 (fr) * 1996-06-11 1998-08-07 Hoechst Marion Roussel Systemes transdermiques renfermant 2 principes actifs dans des compartiments separes, leur procede de preparation et leur application comme medicament
FR2749586B1 (fr) * 1996-06-11 1998-08-07 Hoechst Marion Roussel Inc Nouveaux dispositifs destines a l'administration transdermique de la trimegestone, leur procede de preparation et leur application a titre de medicaments
US5888543A (en) * 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
US5858405A (en) * 1996-07-26 1999-01-12 American Home Products Corporation Oral contraceptive
US6451778B1 (en) 1996-07-26 2002-09-17 Wyeth Oral contraceptive
US6479475B1 (en) 1996-07-26 2002-11-12 Wyeth Oral contraceptive
CA2435350A1 (en) * 2001-02-02 2002-08-15 Pharmacia Corporation Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
TW200306846A (en) * 2002-04-03 2003-12-01 Wyeth Corp Hormone replacement therapy
ITMI20042001A1 (it) 2004-10-21 2005-01-21 Ind Chimica Srl Processo per la preparazione di 21-idrossi steroidi con controllo della distribuzione epimerica nella posizione c-21
DE102005034498A1 (de) * 2005-07-20 2007-01-25 Grünenthal GmbH Orale Kontrazeption mit Trimegeston

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902373A (en) * 1960-01-22 1962-08-01 Pfizer & Co C Steroids and preparation thereof
US3810885A (en) * 1967-12-12 1974-05-14 Roussel Uclaf Novel steroids and processes
FR2077877B1 (es) * 1970-02-20 1974-02-01 Roussel Uclaf
FR2149302A1 (en) * 1971-08-19 1973-03-30 Roussel Uclaf 21-methyl pregnadienes prepn - used as progestomimetics
US3923414A (en) * 1973-07-16 1975-12-02 Valeron Corp Vibration damping support
FR2385737A1 (fr) * 1977-04-01 1978-10-27 Roussel Uclaf Nouveaux steroides, leur procede de preparation et leur application dans la synthese de steroides marques au tritium
FR2374335A1 (fr) * 1976-12-14 1978-07-13 Roussel Uclaf Nouveaux steroides, leur procede de preparation et leur application dans la synthese de steroides marques au tritium
JPS5894940U (ja) * 1981-12-21 1983-06-28 日野自動車株式会社 ビスカスダンパ

Also Published As

Publication number Publication date
EP0007823A2 (fr) 1980-02-06
JPH027600B2 (es) 1990-02-19
DK165637C (da) 1993-06-01
ZA793453B (en) 1980-06-25
ATE8899T1 (de) 1984-08-15
HU178088B (en) 1982-03-28
CA1131215A (fr) 1982-09-07
DK136391A (da) 1991-07-16
US4273771A (en) 1981-06-16
DK292579A (da) 1980-01-14
AU4889579A (en) 1980-01-17
DE2965904D1 (en) 1983-08-25
EP0007823A3 (en) 1980-05-14
FR2430953B1 (es) 1981-09-11
IE791339L (en) 1980-01-13
FR2430953A1 (fr) 1980-02-08
AU527592B2 (en) 1983-03-10
PT69903A (fr) 1979-08-01
DK163361B (da) 1992-02-24
EP0046001B1 (fr) 1984-08-08
IE49457B1 (en) 1985-10-16
IL57691A (en) 1983-10-31
JPS6254119B2 (es) 1987-11-13
EP0046001A1 (fr) 1982-02-17
JPS6333395A (ja) 1988-02-13
EP0007823B1 (fr) 1983-07-20
IL57691A0 (en) 1979-10-31
DK165637B (da) 1992-12-28
DK136391D0 (da) 1991-07-16
DK163361C (da) 1992-07-13
JPS5515475A (en) 1980-02-02

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