ES476913A1 - Tetradeca peptides - Google Patents

Tetradeca peptides

Info

Publication number
ES476913A1
ES476913A1 ES476913A ES476913A ES476913A1 ES 476913 A1 ES476913 A1 ES 476913A1 ES 476913 A ES476913 A ES 476913A ES 476913 A ES476913 A ES 476913A ES 476913 A1 ES476913 A1 ES 476913A1
Authority
ES
Spain
Prior art keywords
compounds
novel
tetradeca
peptides
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476913A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US04/874,173 external-priority patent/US4151394A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES476913A1 publication Critical patent/ES476913A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Novel, therapeutically active compounds have the following formula < IMAGE > in which Y denotes D-Val or D-Ala. The compounds can also be in the form of pharmaceutically acceptable acid addition salts. The compounds of the formula I are prepared by oxidising a corresponding tetradecapeptide, the two sulphydryl groups being converted into a disulphide bridge. The novel compounds can be used for inhibiting the release of growth hormones and for reducing intestinal motility.
ES476913A 1977-04-21 1979-01-16 Tetradeca peptides Expired ES476913A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78947377A 1977-04-21 1977-04-21
US04/874,173 US4151394A (en) 1978-02-01 1978-02-01 Guidance system for arc welder

Publications (1)

Publication Number Publication Date
ES476913A1 true ES476913A1 (en) 1979-09-16

Family

ID=27120917

Family Applications (2)

Application Number Title Priority Date Filing Date
ES469004A Expired ES469004A1 (en) 1977-04-21 1978-04-20 Tetradeca peptides
ES476913A Expired ES476913A1 (en) 1977-04-21 1979-01-16 Tetradeca peptides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES469004A Expired ES469004A1 (en) 1977-04-21 1978-04-20 Tetradeca peptides

Country Status (23)

Country Link
JP (1) JPS53132589A (en)
AR (1) AR229798A1 (en)
AT (1) AT360675B (en)
AU (1) AU518731B2 (en)
BG (2) BG28705A4 (en)
CA (1) CA1120030A (en)
CH (1) CH634040A5 (en)
DD (1) DD136739A5 (en)
DE (1) DE2816855A1 (en)
DK (1) DK174178A (en)
EG (1) EG14800A (en)
ES (2) ES469004A1 (en)
FI (1) FI64575C (en)
FR (1) FR2387942A1 (en)
GB (1) GB1596329A (en)
GR (1) GR69789B (en)
IE (1) IE46617B1 (en)
IL (1) IL54532A (en)
IT (1) IT1094471B (en)
NL (1) NL7804219A (en)
NZ (1) NZ187010A (en)
PT (1) PT67912B (en)
SE (1) SE7804398L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8423431D0 (en) * 1984-09-17 1984-10-24 Sandoz Ltd Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2608336A1 (en) * 1975-03-11 1976-09-30 Sandoz Ag NEW ORGANIC COMPOUNDS, THEIR PRODUCTION AND USE
US4372884A (en) * 1975-08-06 1983-02-08 The Salk Institute For Biological Studies Pharmaceutically active peptides

Also Published As

Publication number Publication date
ES469004A1 (en) 1979-09-01
DK174178A (en) 1978-10-22
JPS53132589A (en) 1978-11-18
CA1120030A (en) 1982-03-16
GR69789B (en) 1982-07-07
FI781183A (en) 1978-10-22
GB1596329A (en) 1981-08-26
SE7804398L (en) 1978-10-22
EG14800A (en) 1985-06-30
FI64575B (en) 1983-08-31
IL54532A0 (en) 1978-07-31
DE2816855A1 (en) 1978-11-02
AR229798A1 (en) 1983-11-30
BG28704A3 (en) 1980-06-16
NZ187010A (en) 1980-08-26
PT67912B (en) 1979-11-14
ATA282978A (en) 1980-06-15
NL7804219A (en) 1978-10-24
IL54532A (en) 1983-03-31
AU518731B2 (en) 1981-10-15
AU3534178A (en) 1979-10-25
IT1094471B (en) 1985-08-02
AT360675B (en) 1981-01-26
FI64575C (en) 1983-12-12
BG28705A4 (en) 1980-06-16
IT7822553A0 (en) 1978-04-20
FR2387942A1 (en) 1978-11-17
IE780766L (en) 1978-10-21
PT67912A (en) 1978-05-01
CH634040A5 (en) 1983-01-14
DD136739A5 (en) 1979-07-25
FR2387942B1 (en) 1981-06-26
IE46617B1 (en) 1983-08-10

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