ES476343A1 - Procedimiento para la obtencion de ciclopentan-1-aminas - Google Patents

Procedimiento para la obtencion de ciclopentan-1-aminas

Info

Publication number
ES476343A1
ES476343A1 ES476343A ES476343A ES476343A1 ES 476343 A1 ES476343 A1 ES 476343A1 ES 476343 A ES476343 A ES 476343A ES 476343 A ES476343 A ES 476343A ES 476343 A1 ES476343 A1 ES 476343A1
Authority
ES
Spain
Prior art keywords
atoms
alkyl
hydrogen
cyclopentan
amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476343A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES476343A1 publication Critical patent/ES476343A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • C07D303/06—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms in which the oxirane rings are condensed with a carbocyclic ring system having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la obtención de diclopentan-1-aminas, de fórmula I donde R1 y R2 significan hidrógeno o bencilo, R3 significa alquilo con 5 a 10 átomos de carbono ó 2 hidroxialquilo con 5 a 10 átomos de carbono, R4 significa hodrógeno, metilo o etilo, R5 significa alquilo con 5 a 10 átomos de carbono o ¿CnH2nCOOR6, R6 significa hidrógeno o alquilo con 1 o 4 átomos de carbono y n representa 0,4,5 ó 6 *** ver imagen 01 *** ver imagen 02
ES476343A 1976-12-23 1978-12-26 Procedimiento para la obtencion de ciclopentan-1-aminas Expired ES476343A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762658401 DE2658401A1 (de) 1976-12-23 1976-12-23 Cyclopentan-1-amine, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel

Publications (1)

Publication Number Publication Date
ES476343A1 true ES476343A1 (es) 1979-10-16

Family

ID=5996379

Family Applications (2)

Application Number Title Priority Date Filing Date
ES465384A Expired ES465384A1 (es) 1976-12-23 1977-12-23 Procedimiento para la obtencion de ciclopentan-1-aminas
ES476343A Expired ES476343A1 (es) 1976-12-23 1978-12-26 Procedimiento para la obtencion de ciclopentan-1-aminas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES465384A Expired ES465384A1 (es) 1976-12-23 1977-12-23 Procedimiento para la obtencion de ciclopentan-1-aminas

Country Status (13)

Country Link
US (1) US4188403A (es)
JP (1) JPS5379844A (es)
AT (1) ATA922877A (es)
AU (1) AU3191677A (es)
BE (1) BE862231A (es)
DE (1) DE2658401A1 (es)
ES (2) ES465384A1 (es)
FR (1) FR2375187A1 (es)
GB (1) GB1547127A (es)
IL (1) IL53650A0 (es)
NL (1) NL7714258A (es)
SE (1) SE7714592L (es)
ZA (1) ZA777611B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3162659D1 (en) * 1980-07-22 1984-04-19 Ono Pharmaceutical Co 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof
CH646148A5 (de) * 1981-05-12 1984-11-15 Gyogyszerkutato Intezet 16-amino-prostaglandin-derivate und verfahren zu ihrer herstellung.
DK218985A (da) * 1984-05-18 1985-11-19 Glaxo Group Ltd Aminocyklopentylaetere, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af dem
US5066824A (en) * 1990-05-15 1991-11-19 Mobay Corporation Novel process for the preparation of amine-terminated compounds
US5449830A (en) * 1994-03-11 1995-09-12 Marck & Co., Inc. Regiospecific processes to make CIS-1-Amino-2-Alkanol from Diol or Halohydrin
AU751772C (en) 1998-04-01 2006-09-07 Correvio International Sàrl Aminocyclohexyl ether compounds and uses thereof
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7057053B2 (en) 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
US20070099983A1 (en) 2003-05-02 2007-05-03 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
WO2005018635A2 (en) 2003-08-07 2005-03-03 Cardiome Pharma Corp. Ion channel modulating activity i
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
US8058304B2 (en) 2004-04-01 2011-11-15 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
WO2005113011A2 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
EP1868598B1 (en) 2004-11-08 2014-04-23 Cardiome Pharma Corp. A new dosing regimen for ion channel modulating compounds for treating acute atrial fibrillation in a human
JP5289971B2 (ja) * 2005-12-22 2013-09-11 ビーエーエスエフ ソシエタス・ヨーロピア Ｏ−アルキル化アミノアルコールの製造方法
WO2007074047A1 (de) * 2005-12-22 2007-07-05 Basf Se Verfahren zur herstellung von zyklischen o-alkylierten aminoalkoholen
KR102527797B1 (ko) 2012-12-21 2023-05-03 길리애드 사이언시즈, 인코포레이티드 폴리시클릭-카르바모일피리돈 화합물 및 그의 제약 용도
CA2916993C (en) 2013-07-12 2019-01-15 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
NO2865735T3 (es) 2013-07-12 2018-07-21
NO2717902T3 (es) 2014-06-20 2018-06-23
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2244778C3 (de) * 1972-09-13 1975-02-20 Th. Goldschmidt Ag, 4300 Essen 1 -n-Dodecylaminomethyl-2-aminocyclopentan, dessen Herstellung und Verwendung als mikrobicider Wirkstoff
DE2259260A1 (de) * 1972-12-04 1974-06-06 Merck Patent Gmbh Neue amine

Also Published As

Publication number Publication date
FR2375187A1 (fr) 1978-07-21
FR2375187B1 (es) 1980-04-04
GB1547127A (en) 1979-06-06
SE7714592L (sv) 1978-06-24
JPS5379844A (en) 1978-07-14
DE2658401A1 (de) 1978-07-06
ATA922877A (de) 1980-07-15
AU3191677A (en) 1979-06-28
IL53650A0 (en) 1978-03-10
US4188403A (en) 1980-02-12
ZA777611B (en) 1978-10-25
ES465384A1 (es) 1979-01-01
NL7714258A (nl) 1978-06-27
BE862231A (nl) 1978-06-23

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