ES471766A1 - Parainfluenza virus vaccine and its preparation. - Google Patents

Parainfluenza virus vaccine and its preparation.

Info

Publication number
ES471766A1
ES471766A1 ES471766A ES471766A ES471766A1 ES 471766 A1 ES471766 A1 ES 471766A1 ES 471766 A ES471766 A ES 471766A ES 471766 A ES471766 A ES 471766A ES 471766 A1 ES471766 A1 ES 471766A1
Authority
ES
Spain
Prior art keywords
parainfluenza virus
preparation
virus vaccine
virus
live
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471766A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES471766A1 publication Critical patent/ES471766A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

By serially passaging a previously isolated and adapted virulent parainfluenza virus in tissue culture prepared from embryonated hens' eggs, a live, non-pathogenic but antigenic parainfluenza virus is produced. This virus is useful in preparing a live virus vaccine.
ES471766A 1977-07-22 1978-07-14 Parainfluenza virus vaccine and its preparation. Expired ES471766A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81795577A 1977-07-22 1977-07-22

Publications (1)

Publication Number Publication Date
ES471766A1 true ES471766A1 (en) 1979-10-01

Family

ID=25224287

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471766A Expired ES471766A1 (en) 1977-07-22 1978-07-14 Parainfluenza virus vaccine and its preparation.

Country Status (9)

Country Link
EP (1) EP0000677B1 (en)
JP (1) JPS5444015A (en)
DE (1) DE2860895D1 (en)
DK (1) DK326878A (en)
EG (1) EG14362A (en)
ES (1) ES471766A1 (en)
IT (1) IT1105533B (en)
PT (1) PT68284A (en)
ZA (1) ZA784161B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215107A (en) * 1978-12-29 1980-07-29 Merck & Co., Inc. Parainfluenza virus vaccine and its preparation
EP0310317B1 (en) * 1987-09-28 1993-12-15 Beecham Inc. Inactivation of viruses and bacteria

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5317049B2 (en) * 1972-08-25 1978-06-06

Also Published As

Publication number Publication date
JPS5444015A (en) 1979-04-07
DK326878A (en) 1979-01-23
EP0000677A1 (en) 1979-02-07
IT7850293A0 (en) 1978-07-13
PT68284A (en) 1978-08-01
EG14362A (en) 1984-03-31
IT1105533B (en) 1985-11-04
DE2860895D1 (en) 1981-11-05
EP0000677B1 (en) 1981-08-05
ZA784161B (en) 1980-02-27

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