ES460621A1 - Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. - Google Patents
Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida.Info
- Publication number
- ES460621A1 ES460621A1 ES460621A ES460621A ES460621A1 ES 460621 A1 ES460621 A1 ES 460621A1 ES 460621 A ES460621 A ES 460621A ES 460621 A ES460621 A ES 460621A ES 460621 A1 ES460621 A1 ES 460621A1
- Authority
- ES
- Spain
- Prior art keywords
- sulfamoylbenzamide
- pyrrolidylmethyl
- dimethoxy
- allyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento de síntesis de N-(1'-alil-2'-pirrolidilmetil)-2, 3-dimetoxi-5-sulfamoil-benzamida, sus sales de amonio cuaternario, su óxido, sus sales de adición de ácidos farmacológicamente aceptables y sus isómeros dextrógiro y levógiro, *** ver imagen 01 Caracterizado porque se hacer reaccionar el compuesto de fórmula *** ver imagen 02 enla que X es un radical hidroxilo, un átomo de halógeno o un resto orgánico, con la l-alil-2-aminometilpirrolidina o con sus derivados reactivos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7622180A FR2358892A1 (fr) | 1976-07-19 | 1976-07-19 | N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES460621A1 true ES460621A1 (es) | 1978-05-01 |
Family
ID=9175947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES460621A Expired ES460621A1 (es) | 1976-07-19 | 1977-07-11 | Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. |
Country Status (38)
Country | Link |
---|---|
US (1) | US4499019A (es) |
JP (1) | JPS5338631A (es) |
AR (1) | AR214330A1 (es) |
AT (1) | AT365570B (es) |
AU (1) | AU509291B2 (es) |
BE (1) | BE856289A (es) |
CH (1) | CH627162A5 (es) |
CS (1) | CS219885B2 (es) |
CY (1) | CY1036A (es) |
DD (2) | DD132492A5 (es) |
DK (1) | DK156646C (es) |
EG (1) | EG12911A (es) |
ES (1) | ES460621A1 (es) |
FI (1) | FI67213C (es) |
FR (1) | FR2358892A1 (es) |
GB (1) | GB1539319A (es) |
GR (1) | GR60836B (es) |
HK (1) | HK17880A (es) |
HU (1) | HU174981B (es) |
IE (1) | IE46171B1 (es) |
IL (1) | IL52547A (es) |
IN (1) | IN146993B (es) |
LU (1) | LU77782A1 (es) |
MC (1) | MC1153A1 (es) |
MX (1) | MX4711E (es) |
NL (1) | NL174347C (es) |
NO (1) | NO146598C (es) |
NZ (1) | NZ184634A (es) |
OA (1) | OA05704A (es) |
PH (1) | PH12838A (es) |
PL (1) | PL104244B1 (es) |
PT (1) | PT66819B (es) |
RO (1) | RO71691A (es) |
SE (1) | SE425243B (es) |
SU (1) | SU695556A3 (es) |
YU (1) | YU40677B (es) |
ZA (1) | ZA774256B (es) |
ZM (1) | ZM5477A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2438650A1 (fr) * | 1978-10-11 | 1980-05-09 | Ile De France | N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire |
JPS5639431A (en) * | 1979-09-06 | 1981-04-15 | Susumu Yagyu | Colorimeter having two-light pass length and two-wave length |
FR2478093A1 (fr) * | 1980-03-12 | 1981-09-18 | Ile De France | Nouveau procede de preparation de n-(1-alkyl (ou allyl) 2-pyrrolidinyl-methyl)2-methoxy (ou 2,3-dimethoxy) 5-sulfamoyl (ou sulfamoyl substitue) |
FR2550447B1 (fr) * | 1983-08-10 | 1986-01-17 | Ile De France | Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire |
FR2584605B1 (fr) * | 1985-07-15 | 1988-06-17 | Ile De France | Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson |
US7645750B2 (en) * | 2006-12-13 | 2010-01-12 | Yung Shin Pharmaceutical Ind. Co., Ltd. | Method of treating symptoms of hormonal variations |
US8420624B2 (en) * | 2007-12-04 | 2013-04-16 | Yung Shin Pharm. Ind. Co., Ltd. | Methods for treating or preventing symptoms of hormonal variations |
CN105481733A (zh) * | 2015-12-30 | 2016-04-13 | 苏州诚和医药化学有限公司 | 一种一步法合成2-甲氧基-5-氨磺酰基苯甲酸甲酯的方法 |
-
1976
- 1976-07-19 FR FR7622180A patent/FR2358892A1/fr active Granted
-
1977
- 1977-05-24 CY CY1036A patent/CY1036A/xx unknown
- 1977-05-24 GB GB21883/77A patent/GB1539319A/en not_active Expired
- 1977-06-30 BE BE1008238A patent/BE856289A/xx not_active IP Right Cessation
- 1977-07-05 MC MC771249A patent/MC1153A1/xx unknown
- 1977-07-05 OA OA56219A patent/OA05704A/xx unknown
- 1977-07-08 PH PH19975A patent/PH12838A/en unknown
- 1977-07-08 ZM ZM54/77A patent/ZM5477A1/xx unknown
- 1977-07-11 AR AR268387A patent/AR214330A1/es active
- 1977-07-11 EG EG413/77A patent/EG12911A/xx active
- 1977-07-11 ES ES460621A patent/ES460621A1/es not_active Expired
- 1977-07-12 GR GR53944A patent/GR60836B/el unknown
- 1977-07-13 NZ NZ184634A patent/NZ184634A/xx unknown
- 1977-07-13 YU YU1739/77A patent/YU40677B/xx unknown
- 1977-07-13 CH CH867977A patent/CH627162A5/fr not_active IP Right Cessation
- 1977-07-14 SE SE7708176A patent/SE425243B/xx not_active IP Right Cessation
- 1977-07-14 AU AU27026/77A patent/AU509291B2/en not_active Expired
- 1977-07-15 IE IE1482/77A patent/IE46171B1/en not_active IP Right Cessation
- 1977-07-15 HU HU77SO1193A patent/HU174981B/hu unknown
- 1977-07-15 NO NO772530A patent/NO146598C/no unknown
- 1977-07-15 DD DD7700200091A patent/DD132492A5/xx not_active IP Right Cessation
- 1977-07-15 LU LU77782A patent/LU77782A1/xx unknown
- 1977-07-15 JP JP8552977A patent/JPS5338631A/ja active Granted
- 1977-07-15 MX MX775905U patent/MX4711E/es unknown
- 1977-07-15 DD DD77207969A patent/DD137670A5/xx not_active IP Right Cessation
- 1977-07-15 AT AT0511677A patent/AT365570B/de not_active IP Right Cessation
- 1977-07-15 PT PT66819A patent/PT66819B/pt unknown
- 1977-07-18 DK DK326377A patent/DK156646C/da not_active IP Right Cessation
- 1977-07-18 FI FI772214A patent/FI67213C/fi not_active IP Right Cessation
- 1977-07-18 PL PL1977199723A patent/PL104244B1/pl unknown
- 1977-07-18 NL NLAANVRAGE7707982,A patent/NL174347C/xx not_active IP Right Cessation
- 1977-07-18 IL IL52547A patent/IL52547A/xx unknown
- 1977-07-19 SU SU772504152A patent/SU695556A3/ru active
- 1977-07-19 CS CS774811A patent/CS219885B2/cs unknown
- 1977-07-19 RO RO7791091A patent/RO71691A/ro unknown
- 1977-08-23 IN IN1318/CAL/77A patent/IN146993B/en unknown
-
1978
- 1978-05-12 ZA ZA00774256A patent/ZA774256B/xx unknown
-
1980
- 1980-04-03 HK HK178/80A patent/HK17880A/xx unknown
-
1983
- 1983-10-13 US US06/540,918 patent/US4499019A/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO154918C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. | |
IT7821872A0 (it) | Derivati d'acetammide impiegabili segnatamente in terapia, eprocedimento per produrli. | |
IT7829043A0 (it) | Polisaccaride avente attivita'anti-tumorale, procedimento per lasua produzione e sostanza anti-tumorale comprendente detto polisaccaride. | |
IT1083903B (it) | Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche | |
DK140583B (da) | Operationsstol for en behandlende læge. | |
RO71931A (ro) | Procedeu pentru prepararea unor feniletilamino-derivati ai 3,4-dihidro-2h-izochinolin-1-onei sau ai 1,2,3,4-tetrahidro-5h-benzazepin-1-onei | |
BE848496A (fr) | Derives d'amino-alcools, leur preparation et utilisation, ainsi que compositions contenant ces derives. | |
IT1067959B (it) | Laminato tessile,nonche' procedimento e dispositivo per la sua fabbricazione | |
RO75777A (ro) | Procedeu pentru prepararea unor 1,2-benzizotiazolin-3-one | |
ES460621A1 (es) | Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. | |
NL7806912A (nl) | N'fenyl-n-methyl-ureumderivaten, de bereidingswijze en toepassing daarvan. | |
RO81681A (ro) | Procedeu pentru prepararea unor 1,2,3-tiadiazol-3-in-5-ilidenuree | |
RO76721A (ro) | Procedeu pentru prepararea 3.12.-hidroxi-4-fenil-cicloalcanonei | |
MY102991A (en) | Medicaments for treating hypertension. | |
SE408412B (sv) | Forfarande for framstellning av l-3-(3,4-dihydroxi-fenyl)-2-metyl-alanin-peptider med blodtryckssenkande egenskaper | |
AR218498A1 (es) | Procedimiento de preparacion de derivados de 1,3-difenoxipropan-2-ona | |
IT1079246B (it) | Potrona d'intervento per gabinetti medici,dentisti e simili | |
RO81212A (ro) | Procedeu pentru prepararea unor 2',6'-dialchil-n-(alcoximetil)2-cloracetanilide | |
FR2315921A1 (fr) | Thioindoles substitues sur l'atome de soufre et eventuellement sur le noyau indole, procede de preparation de ceux-ci, et agents therapeutiques en comportant application | |
SE7603223L (sv) | 13,14-dehydro-11-deoxi-prostaglandiner och forfarande for deras framstellning | |
FR2415107A1 (fr) | Derives de 5-phenethyl-2-oxazolidone, leur procede de preparation et leur application en therapeutique | |
FR2363541A1 (fr) | Acyloxy-n,n' diacylmalonamides et leur mode de preparation | |
IT1118225B (it) | Procedimento per l'ottenimento di steroidi poliossidrilati,lisergolo ed alcaloidi ergolici | |
SE7708824L (sv) | Forfarande for framstellning av 2,6-di-tert butylfenol | |
BE842528R (fr) | Derives actifs de methylamine, compositions therapeutiques les contenant ainsi que les procedes de preparation de ces derives et compositions |