ES460621A1 - Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. - Google Patents

Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida.

Info

Publication number
ES460621A1
ES460621A1 ES460621A ES460621A ES460621A1 ES 460621 A1 ES460621 A1 ES 460621A1 ES 460621 A ES460621 A ES 460621A ES 460621 A ES460621 A ES 460621A ES 460621 A1 ES460621 A1 ES 460621A1
Authority
ES
Spain
Prior art keywords
sulfamoylbenzamide
pyrrolidylmethyl
dimethoxy
allyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES460621A
Other languages
English (en)
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of ES460621A1 publication Critical patent/ES460621A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento de síntesis de N-(1'-alil-2'-pirrolidilmetil)-2, 3-dimetoxi-5-sulfamoil-benzamida, sus sales de amonio cuaternario, su óxido, sus sales de adición de ácidos farmacológicamente aceptables y sus isómeros dextrógiro y levógiro, *** ver imagen 01 Caracterizado porque se hacer reaccionar el compuesto de fórmula *** ver imagen 02 enla que X es un radical hidroxilo, un átomo de halógeno o un resto orgánico, con la l-alil-2-aminometilpirrolidina o con sus derivados reactivos.
ES460621A 1976-07-19 1977-07-11 Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. Expired ES460621A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7622180A FR2358892A1 (fr) 1976-07-19 1976-07-19 N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives

Publications (1)

Publication Number Publication Date
ES460621A1 true ES460621A1 (es) 1978-05-01

Family

ID=9175947

Family Applications (1)

Application Number Title Priority Date Filing Date
ES460621A Expired ES460621A1 (es) 1976-07-19 1977-07-11 Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida.

Country Status (38)

Country Link
US (1) US4499019A (es)
JP (1) JPS5338631A (es)
AR (1) AR214330A1 (es)
AT (1) AT365570B (es)
AU (1) AU509291B2 (es)
BE (1) BE856289A (es)
CH (1) CH627162A5 (es)
CS (1) CS219885B2 (es)
CY (1) CY1036A (es)
DD (2) DD132492A5 (es)
DK (1) DK156646C (es)
EG (1) EG12911A (es)
ES (1) ES460621A1 (es)
FI (1) FI67213C (es)
FR (1) FR2358892A1 (es)
GB (1) GB1539319A (es)
GR (1) GR60836B (es)
HK (1) HK17880A (es)
HU (1) HU174981B (es)
IE (1) IE46171B1 (es)
IL (1) IL52547A (es)
IN (1) IN146993B (es)
LU (1) LU77782A1 (es)
MC (1) MC1153A1 (es)
MX (1) MX4711E (es)
NL (1) NL174347C (es)
NO (1) NO146598C (es)
NZ (1) NZ184634A (es)
OA (1) OA05704A (es)
PH (1) PH12838A (es)
PL (1) PL104244B1 (es)
PT (1) PT66819B (es)
RO (1) RO71691A (es)
SE (1) SE425243B (es)
SU (1) SU695556A3 (es)
YU (1) YU40677B (es)
ZA (1) ZA774256B (es)
ZM (1) ZM5477A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2438650A1 (fr) * 1978-10-11 1980-05-09 Ile De France N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire
JPS5639431A (en) * 1979-09-06 1981-04-15 Susumu Yagyu Colorimeter having two-light pass length and two-wave length
FR2478093A1 (fr) * 1980-03-12 1981-09-18 Ile De France Nouveau procede de preparation de n-(1-alkyl (ou allyl) 2-pyrrolidinyl-methyl)2-methoxy (ou 2,3-dimethoxy) 5-sulfamoyl (ou sulfamoyl substitue)
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2584605B1 (fr) * 1985-07-15 1988-06-17 Ile De France Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson
US7645750B2 (en) * 2006-12-13 2010-01-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Method of treating symptoms of hormonal variations
US8420624B2 (en) * 2007-12-04 2013-04-16 Yung Shin Pharm. Ind. Co., Ltd. Methods for treating or preventing symptoms of hormonal variations
CN105481733A (zh) * 2015-12-30 2016-04-13 苏州诚和医药化学有限公司 一种一步法合成2-甲氧基-5-氨磺酰基苯甲酸甲酯的方法

Also Published As

Publication number Publication date
RO71691A (ro) 1982-09-09
MX4711E (es) 1982-08-11
DK156646C (da) 1990-02-05
MC1153A1 (fr) 1978-04-17
FR2358892B1 (es) 1978-12-15
PT66819A (fr) 1977-08-01
FI67213C (fi) 1985-02-11
CS219885B2 (en) 1983-03-25
IL52547A (en) 1980-01-31
PL104244B1 (pl) 1979-08-31
IE46171L (en) 1978-01-19
OA05704A (fr) 1981-05-31
IN146993B (es) 1979-10-20
FI67213B (fi) 1984-10-31
NO772530L (no) 1978-01-20
DK156646B (da) 1989-09-18
JPS5338631A (en) 1978-04-08
SU695556A3 (ru) 1979-10-30
FR2358892A1 (fr) 1978-02-17
AT365570B (de) 1982-01-25
LU77782A1 (es) 1977-10-17
NL174347C (nl) 1984-06-01
US4499019A (en) 1985-02-12
SE7708176L (sv) 1978-01-20
NO146598C (no) 1982-11-03
YU173977A (en) 1983-01-21
HK17880A (en) 1980-04-11
IE46171B1 (en) 1983-03-23
GB1539319A (en) 1979-01-31
AU509291B2 (en) 1980-05-01
CH627162A5 (es) 1981-12-31
SE425243B (sv) 1982-09-13
AR214330A1 (es) 1979-05-31
NO146598B (no) 1982-07-26
FI772214A (es) 1978-01-20
AU2702677A (en) 1979-01-18
ZA774256B (en) 1978-06-28
YU40677B (en) 1986-04-30
NL7707982A (nl) 1978-01-23
CY1036A (en) 1980-08-01
DD132492A5 (de) 1978-10-04
NL174347B (nl) 1984-01-02
DD137670A5 (de) 1979-09-19
PT66819B (fr) 1978-12-22
HU174981B (hu) 1980-04-28
PL199723A1 (pl) 1978-04-24
JPS554724B2 (es) 1980-01-31
GR60836B (en) 1978-08-31
DK326377A (da) 1978-01-20
ATA511677A (de) 1981-06-15
ZM5477A1 (en) 1978-05-22
EG12911A (en) 1980-12-31
IL52547A0 (en) 1977-10-31
BE856289A (fr) 1977-12-30
NZ184634A (en) 1978-11-13
PH12838A (en) 1979-09-05

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