ES458411A1 - Immunoassay procedure and composite therefor - Google Patents

Immunoassay procedure and composite therefor

Info

Publication number
ES458411A1
ES458411A1 ES458411A ES458411A ES458411A1 ES 458411 A1 ES458411 A1 ES 458411A1 ES 458411 A ES458411 A ES 458411A ES 458411 A ES458411 A ES 458411A ES 458411 A1 ES458411 A1 ES 458411A1
Authority
ES
Spain
Prior art keywords
composite
immunoassay procedure
coupling agent
therefor
bifunctional coupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458411A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/682,830 external-priority patent/US4081246A/en
Priority claimed from US05/682,807 external-priority patent/US4081244A/en
Priority claimed from US05/682,808 external-priority patent/US4081245A/en
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of ES458411A1 publication Critical patent/ES458411A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody

Abstract

A solution is placed in contact with a composite comprising a matrix of a polysaccharide derivative covalently linked to an antibody by a bifunctional coupling agent, and then the solution containing the free fractions is separated from the composite which has reacted. The separation is particularly effective by virtue of the use, as bifunctional coupling agent, of a compound of formula I in which n represents an integer from 1 to 6 and e is equal to 1 or 2.
ES458411A 1976-05-03 1977-05-03 Immunoassay procedure and composite therefor Expired ES458411A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/682,830 US4081246A (en) 1976-05-03 1976-05-03 Solid phase column immunoassay procedure employing novel immunochemical composites
US05/682,807 US4081244A (en) 1976-05-03 1976-05-03 Immunoassay procedure employing novel immunochemical composites
US05/682,808 US4081245A (en) 1976-05-03 1976-05-03 Immunoassay procedure employing novel immunochemical composites

Publications (1)

Publication Number Publication Date
ES458411A1 true ES458411A1 (en) 1978-12-01

Family

ID=27418405

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458411A Expired ES458411A1 (en) 1976-05-03 1977-05-03 Immunoassay procedure and composite therefor

Country Status (10)

Country Link
JP (1) JPS52134020A (en)
AU (1) AU510210B2 (en)
CH (1) CH629894A5 (en)
DE (1) DE2719772A1 (en)
ES (1) ES458411A1 (en)
FR (1) FR2361414A1 (en)
GB (1) GB1588253A (en)
IT (1) IT1081386B (en)
NL (1) NL7704784A (en)
NZ (1) NZ183970A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54147913A (en) * 1978-05-12 1979-11-19 Unitika Ltd Preparation of immunoadsorbent
FR2459479B1 (en) * 1979-06-21 1983-07-08 Inst Nat Sante Rech Med PROCESS FOR SEPARATING A PROTEIN SUBSTANCE FROM A SOLUTION CONTAINING IT BY AFFINITY FILTRATION AND APPLICATION OF SAID METHOD FOR ENZYMATIC ASSAYS
DE3019163C2 (en) 1980-05-20 1984-07-26 B.A.T. Cigaretten-Fabriken Gmbh, 2000 Hamburg Use of cellulose fibers containing amino groups as a material for tobacco smoke filters
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
DE4140142A1 (en) * 1991-12-05 1993-06-09 Boehringer Mannheim Gmbh, 6800 Mannheim, De MULTIVALENT DEXTRANREAGENT FOR USE IN PRECIPITATION TESTS
DE4229378A1 (en) * 1992-09-03 1994-03-10 Daimler Benz Ag Tube-section union with adhesive components - comprises segments alternately overlapping adjacent sections, adhesion being by hook-pile fasteners butting together

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867366A (en) * 1972-11-06 1975-02-18 Synvar Associates A K A Syva C Opiate imidates and protein conjugates thereof

Also Published As

Publication number Publication date
JPS52134020A (en) 1977-11-09
AU510210B2 (en) 1980-06-12
DE2719772A1 (en) 1977-11-24
GB1588253A (en) 1981-04-23
NZ183970A (en) 1979-06-08
FR2361414A1 (en) 1978-03-10
CH629894A5 (en) 1982-05-14
NL7704784A (en) 1977-11-07
AU2471977A (en) 1978-11-02
FR2361414B1 (en) 1982-11-19
IT1081386B (en) 1985-05-21

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