ES456591A1 - Un procedimiento para preparar un isomero l de un compuesto de cefalosporina. - Google Patents
Un procedimiento para preparar un isomero l de un compuesto de cefalosporina.Info
- Publication number
- ES456591A1 ES456591A1 ES456591A ES456591A ES456591A1 ES 456591 A1 ES456591 A1 ES 456591A1 ES 456591 A ES456591 A ES 456591A ES 456591 A ES456591 A ES 456591A ES 456591 A1 ES456591 A1 ES 456591A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alcohol
- heterothiomethyl
- cephalosporins
- ureido
- isomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- -1 ureido cephalosporins Chemical class 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 5
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003638 stannyl group Chemical group [H][Sn]([H])([H])* 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para preparar un isómero L de un compuesto de cefalosporina de la fórmula **(Fórmula)** donde R1 es fenilo, tienilo o furilo, R3 está seleccionado del grupo que consta de hidrógeno, alcohilo inferior fenil-alcohilo inferior, difenil-alcohilo inferior, tri(alcohilo inferior) sililo, tri(alcohilo inferior)estannilo, un ión formador de sales, fenilo sustituido-alcohilo inferior.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/664,796 US4088816A (en) | 1974-09-20 | 1976-03-08 | 3-Heterothio substituted 7-(ureido-heteroacetyl) cephalosporins |
US05/664,795 US4088815A (en) | 1974-09-20 | 1976-03-08 | 3-Heterothio-7-ureido cephalosporins |
US05/764,134 US4127716A (en) | 1976-03-08 | 1977-02-02 | 3-heterothiomethyl ureido cephalosporins |
Publications (1)
Publication Number | Publication Date |
---|---|
ES456591A1 true ES456591A1 (es) | 1978-02-16 |
Family
ID=27418117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES456591A Expired ES456591A1 (es) | 1976-03-08 | 1977-03-07 | Un procedimiento para preparar un isomero l de un compuesto de cefalosporina. |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS52108996A (es) |
AT (1) | AT352876B (es) |
AU (1) | AU2236777A (es) |
CA (1) | CA1088517A (es) |
CS (1) | CS191190B2 (es) |
DD (1) | DD129793A5 (es) |
DE (1) | DE2707812A1 (es) |
DK (1) | DK97077A (es) |
ES (1) | ES456591A1 (es) |
FR (1) | FR2343745A2 (es) |
GB (1) | GB1573786A (es) |
NL (1) | NL7702405A (es) |
NZ (1) | NZ183332A (es) |
PL (1) | PL196501A1 (es) |
PT (1) | PT66272B (es) |
SE (1) | SE7702558L (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2927534A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung |
-
1977
- 1977-02-14 NZ NZ183332A patent/NZ183332A/xx unknown
- 1977-02-15 CA CA271,818A patent/CA1088517A/en not_active Expired
- 1977-02-17 AU AU22367/77A patent/AU2236777A/en not_active Expired
- 1977-02-23 DE DE19772707812 patent/DE2707812A1/de not_active Ceased
- 1977-03-04 CS CS771474A patent/CS191190B2/cs unknown
- 1977-03-04 DK DK97077A patent/DK97077A/da not_active Application Discontinuation
- 1977-03-07 SE SE7702558A patent/SE7702558L/xx not_active Application Discontinuation
- 1977-03-07 PT PT66272A patent/PT66272B/pt unknown
- 1977-03-07 NL NL7702405A patent/NL7702405A/xx not_active Application Discontinuation
- 1977-03-07 ES ES456591A patent/ES456591A1/es not_active Expired
- 1977-03-07 GB GB9511/77A patent/GB1573786A/en not_active Expired
- 1977-03-08 JP JP2583677A patent/JPS52108996A/ja active Pending
- 1977-03-08 PL PL19650177A patent/PL196501A1/xx unknown
- 1977-03-08 AT AT155177A patent/AT352876B/de not_active IP Right Cessation
- 1977-03-08 DD DD7700197733A patent/DD129793A5/xx unknown
- 1977-03-08 FR FR7706808A patent/FR2343745A2/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
JPS52108996A (en) | 1977-09-12 |
NL7702405A (nl) | 1977-09-12 |
PT66272B (fr) | 1978-08-08 |
ATA155177A (de) | 1979-03-15 |
PT66272A (en) | 1977-03-31 |
GB1573786A (en) | 1980-08-28 |
CS191190B2 (en) | 1979-06-29 |
FR2343745A2 (fr) | 1977-10-07 |
SE7702558L (sv) | 1977-09-09 |
AU2236777A (en) | 1978-08-24 |
DK97077A (da) | 1977-09-09 |
NZ183332A (en) | 1979-10-25 |
AT352876B (de) | 1979-10-10 |
DD129793A5 (de) | 1978-02-08 |
PL196501A1 (pl) | 1978-02-13 |
CA1088517A (en) | 1980-10-28 |
DE2707812A1 (de) | 1977-09-15 |
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