ES453263A1 - Heterocyclic thioalkyl-amines-guanidines and -thioureas - Google Patents
Heterocyclic thioalkyl-amines-guanidines and -thioureasInfo
- Publication number
- ES453263A1 ES453263A1 ES453263A ES453263A ES453263A1 ES 453263 A1 ES453263 A1 ES 453263A1 ES 453263 A ES453263 A ES 453263A ES 453263 A ES453263 A ES 453263A ES 453263 A1 ES453263 A1 ES 453263A1
- Authority
- ES
- Spain
- Prior art keywords
- histamine
- compounds
- useful
- antagonists
- blocked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Process for preparing pharmacologically active compounds, useful for use in pharmaceutical compositions. The compounds produced by the process of this invention have a useful h2 histamine antagonist activity. These compounds can exist as acid addition salts. Histamine h2 antagonists can be defined as compounds that block histamine h2 receptors. H2 histamine receptors are not blocked by mepyramine and typical "antihistamines" (histamine h1 receptor antagonists), but are blocked by burimamide. Histamine h2 antagonists are useful as inhibitors of gastric acid secretion, as anti-inflammatory agents and as agents that act on the cardiovascular system. The products of the process of this invention are represented by the following formula i: ** (formula) **. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB46732/75A GB1573611A (en) | 1975-11-12 | 1975-11-12 | Heterocyclic thioalkyl-amines-guanidines and -thioureas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES453263A1 true ES453263A1 (en) | 1978-01-16 |
Family
ID=10442384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES453263A Expired ES453263A1 (en) | 1975-11-12 | 1976-11-12 | Heterocyclic thioalkyl-amines-guanidines and -thioureas |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5262274A (en) |
| AT (1) | AT350583B (en) |
| AU (1) | AU508143B2 (en) |
| BE (1) | BE848108A (en) |
| CA (1) | CA1070316A (en) |
| DE (1) | DE2649546A1 (en) |
| DK (1) | DK503176A (en) |
| ES (1) | ES453263A1 (en) |
| FI (1) | FI763209A (en) |
| FR (1) | FR2331342A1 (en) |
| GB (1) | GB1573611A (en) |
| HU (1) | HU175667B (en) |
| IE (1) | IE44103B1 (en) |
| IL (1) | IL50748A0 (en) |
| LU (1) | LU76162A1 (en) |
| NL (1) | NL7611590A (en) |
| NO (1) | NO763812L (en) |
| NZ (1) | NZ182309A (en) |
| PT (1) | PT65759B (en) |
| SE (1) | SE7611405L (en) |
| SU (1) | SU634668A3 (en) |
| ZA (1) | ZA766201B (en) |
-
1975
- 1975-11-12 GB GB46732/75A patent/GB1573611A/en not_active Expired
-
1976
- 1976-10-12 NZ NZ182309A patent/NZ182309A/en unknown
- 1976-10-14 SE SE7611405A patent/SE7611405L/en unknown
- 1976-10-18 ZA ZA766201A patent/ZA766201B/en unknown
- 1976-10-19 CA CA263,718A patent/CA1070316A/en not_active Expired
- 1976-10-20 NL NL7611590A patent/NL7611590A/en not_active Application Discontinuation
- 1976-10-21 AU AU18900/76A patent/AU508143B2/en not_active Expired
- 1976-10-22 IL IL50748A patent/IL50748A0/en unknown
- 1976-10-26 PT PT65759A patent/PT65759B/en unknown
- 1976-10-26 IE IE2363/76A patent/IE44103B1/en unknown
- 1976-10-29 DE DE19762649546 patent/DE2649546A1/en not_active Withdrawn
- 1976-11-04 AT AT819776A patent/AT350583B/en active
- 1976-11-08 BE BE172167A patent/BE848108A/en not_active IP Right Cessation
- 1976-11-08 DK DK503176A patent/DK503176A/en not_active Application Discontinuation
- 1976-11-09 NO NO763812A patent/NO763812L/no unknown
- 1976-11-09 FI FI763209A patent/FI763209A/fi not_active Application Discontinuation
- 1976-11-10 LU LU76162A patent/LU76162A1/xx unknown
- 1976-11-10 JP JP51135826A patent/JPS5262274A/en active Pending
- 1976-11-10 FR FR7633962A patent/FR2331342A1/en active Granted
- 1976-11-11 HU HU76SI1548A patent/HU175667B/en unknown
- 1976-11-11 SU SU762418884A patent/SU634668A3/en active
- 1976-11-12 ES ES453263A patent/ES453263A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1573611A (en) | 1980-08-28 |
| DK503176A (en) | 1977-05-13 |
| IL50748A0 (en) | 1976-12-31 |
| FR2331342B1 (en) | 1980-03-07 |
| ZA766201B (en) | 1977-09-28 |
| NL7611590A (en) | 1977-05-16 |
| DE2649546A1 (en) | 1977-05-26 |
| IE44103L (en) | 1977-05-12 |
| AT350583B (en) | 1979-06-11 |
| JPS5262274A (en) | 1977-05-23 |
| SU634668A3 (en) | 1978-11-25 |
| PT65759A (en) | 1976-11-01 |
| HU175667B (en) | 1980-09-28 |
| LU76162A1 (en) | 1977-05-18 |
| ATA819776A (en) | 1978-11-15 |
| IE44103B1 (en) | 1981-08-12 |
| AU1890076A (en) | 1978-04-27 |
| PT65759B (en) | 1978-04-27 |
| AU508143B2 (en) | 1980-03-13 |
| BE848108A (en) | 1977-05-09 |
| NO763812L (en) | 1977-05-13 |
| SE7611405L (en) | 1977-05-13 |
| NZ182309A (en) | 1978-07-10 |
| FI763209A (en) | 1977-05-13 |
| CA1070316A (en) | 1980-01-22 |
| FR2331342A1 (en) | 1977-06-10 |
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