ES452943A1 - Procedimiento para preparar 1,2,3,4-tetrahidro-4-oxo-1-naf- tilisocianato e isotiocianato. - Google Patents

Procedimiento para preparar 1,2,3,4-tetrahidro-4-oxo-1-naf- tilisocianato e isotiocianato.

Info

Publication number
ES452943A1
ES452943A1 ES452943A ES452943A ES452943A1 ES 452943 A1 ES452943 A1 ES 452943A1 ES 452943 A ES452943 A ES 452943A ES 452943 A ES452943 A ES 452943A ES 452943 A1 ES452943 A1 ES 452943A1
Authority
ES
Spain
Prior art keywords
naphthylisocyanate
tetrahydro
oxo
isothiocyanate
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452943A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES452943A1 publication Critical patent/ES452943A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
    • C08G18/751—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring
    • C08G18/752—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group
    • C08G18/757—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group containing at least two isocyanate or isothiocyanate groups linked to the cycloaliphatic ring by means of an aliphatic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para preparar 1,2,3,4-tetrahidro-4-oxo-1-naftilisocianato e isotiocianato, de fórmula: **(fórmula)** en la que X es oxígeno o azufre; la mezcla racémica y los isómeros ópticos del mismo. El tetrahidro-4-oxo-1-naftilisocianato e isotiocianato de fórmula (I), sus mezclas racémicas o sus isómeros ópticamente activos, se pueden preparar mediante las siguientes vías preferidas. Se puede preparar un isocianato de fórmula (I) haciendo reaccionar 1, 2, 3, 4-tetrahidro-4-oxo-1-naftilamina de fórmula (IV) o una sal de adición de ácido de la misma, con fosgeno, en un disolvente anhidro, seleccionado entre benceno, tolueno, clorobenceno, hidrocarburos clorados o xilenos, y si así se desea bajo un manto de un gas inerte, por ejemplo, nitrógeno, a una temperatura entre 20ºC y el punto de ebullición del disolvente seleccionado, hasta que la reacción es prácticamente completa. El isocianato de fórmula (I) así obtenidos se puede utilizar como tal para la preparación de los compuestos de urea reguladores del crecimiento animal.
ES452943A 1975-11-03 1976-11-03 Procedimiento para preparar 1,2,3,4-tetrahidro-4-oxo-1-naf- tilisocianato e isotiocianato. Expired ES452943A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/628,030 US3993677A (en) 1975-11-03 1975-11-03 1,2,3,4-Tetrahydro-4-oxo-1-naphthylisocyanate

Publications (1)

Publication Number Publication Date
ES452943A1 true ES452943A1 (es) 1978-01-16

Family

ID=24517126

Family Applications (1)

Application Number Title Priority Date Filing Date
ES452943A Expired ES452943A1 (es) 1975-11-03 1976-11-03 Procedimiento para preparar 1,2,3,4-tetrahidro-4-oxo-1-naf- tilisocianato e isotiocianato.

Country Status (4)

Country Link
US (1) US3993677A (es)
JP (1) JPS5259143A (es)
ES (1) ES452943A1 (es)
NL (1) NL7612185A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049717A (en) * 1976-05-13 1977-09-20 American Cyanamid Company Novel 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamines and method of preparation thereof
US4041070A (en) * 1976-07-14 1977-08-09 American Cyanamid Company Tetrahydro-4-imino-1-naphthylureas
US4051183A (en) * 1976-09-02 1977-09-27 American Cyanamid Company 1-benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)-urea, a novel and useful intermediate for the preparation of animal growth promoting agents
DE2842539A1 (de) * 1978-09-29 1980-04-10 Bayer Ag 1-isocyanato-anthrachinone
EP0381902A1 (en) * 1989-01-09 1990-08-16 Merrell Dow Pharmaceuticals Inc. Tetralin derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683160A (en) * 1953-03-19 1954-07-06 Du Pont Preparation of aromatic isocyanates
US3576812A (en) * 1968-07-02 1971-04-27 American Home Prod 1,5-methano-3-benzazocine derivatives
US3535322A (en) * 1968-07-02 1970-10-20 American Home Prod 1 - phenyl - 1,5 - methano-3-benzazocine derivatives and process of preparation

Also Published As

Publication number Publication date
NL7612185A (nl) 1977-05-05
JPS5259143A (en) 1977-05-16
US3993677A (en) 1976-11-23

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