ES437100A1 - D-homosteroid lactones - Google Patents

D-homosteroid lactones

Info

Publication number
ES437100A1
ES437100A1 ES437100A ES437100A ES437100A1 ES 437100 A1 ES437100 A1 ES 437100A1 ES 437100 A ES437100 A ES 437100A ES 437100 A ES437100 A ES 437100A ES 437100 A1 ES437100 A1 ES 437100A1
Authority
ES
Spain
Prior art keywords
homosteroid
lactones
general formula
formula
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437100A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES437100A1 publication Critical patent/ES437100A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

A procedure for the preparation of D-homosteroids of the general formula ** (See formula) ** in which the dashed lines at positions 1,2-, 6,7 and 16,17 denote optional links, whose process is characterized in that it comprises isomerizing the 5,10 double bond into a D-homo-steroid of the general formula ** (See formula) ** in which the dashed line at position 16,17 has the meaning indicated above at position 4,5. (Machine-translation by Google Translate, not legally binding)
ES437100A 1973-09-26 1975-04-28 D-homosteroid lactones Expired ES437100A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1376373A CH601352A5 (en) 1973-09-26 1973-09-26

Publications (1)

Publication Number Publication Date
ES437100A1 true ES437100A1 (en) 1977-01-16

Family

ID=4395102

Family Applications (4)

Application Number Title Priority Date Filing Date
ES430369A Expired ES430369A1 (en) 1973-09-26 1974-09-24 D-homosteroid lactones
ES437101A Expired ES437101A1 (en) 1973-09-26 1975-04-28 D-homosteroid lactones
ES437099A Expired ES437099A1 (en) 1973-09-26 1975-04-28 D-homosteroid lactones
ES437100A Expired ES437100A1 (en) 1973-09-26 1975-04-28 D-homosteroid lactones

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES430369A Expired ES430369A1 (en) 1973-09-26 1974-09-24 D-homosteroid lactones
ES437101A Expired ES437101A1 (en) 1973-09-26 1975-04-28 D-homosteroid lactones
ES437099A Expired ES437099A1 (en) 1973-09-26 1975-04-28 D-homosteroid lactones

Country Status (27)

Country Link
US (1) US3920703A (en)
JP (1) JPS5058054A (en)
AR (2) AR207230A1 (en)
AT (1) AT337915B (en)
BE (1) BE820303A (en)
CA (1) CA1025435A (en)
CH (1) CH601352A5 (en)
CS (1) CS178930B2 (en)
DD (1) DD115492A5 (en)
DE (1) DE2445783A1 (en)
DK (1) DK135723B (en)
EG (1) EG11189A (en)
ES (4) ES430369A1 (en)
FI (1) FI53709C (en)
FR (1) FR2244497B1 (en)
GB (1) GB1450884A (en)
HU (1) HU172656B (en)
IE (1) IE39913B1 (en)
IL (1) IL45483A (en)
LU (1) LU70980A1 (en)
NL (1) NL7411617A (en)
NO (1) NO140305C (en)
PH (1) PH10616A (en)
PL (2) PL92396B1 (en)
SE (1) SE7411948L (en)
SU (2) SU612637A3 (en)
ZA (1) ZA745197B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155918A (en) * 1976-10-28 1979-05-22 Hoffmann-La Roche Inc. Novel D-homosteroids
DE2652761C2 (en) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylene-spirolactones, processes for their preparation and pharmaceuticals containing them
AT351191B (en) * 1976-12-20 1979-07-10 Hoffmann La Roche METHOD FOR PRODUCING NEW D-HOMOSTEROIDS
LU77699A1 (en) * 1977-07-06 1979-03-26 Hoffmann La Roche METHOD FOR PRODUCING NEW D-HOMOSTEROIDS
CA1195997A (en) * 1979-02-23 1985-10-29 Andor Furst Dea-steroids
DK23984A (en) * 1983-02-11 1984-08-12 Hoffmann La Roche D-homosteroids
DE3461090D1 (en) * 1983-02-18 1986-12-04 Schering Ag 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3758508A (en) * 1964-09-29 1973-09-11 Hoffmann La Roche Ted derivatives thereof process for the preparation of desaandrostanes pregnanes and unsatura

Also Published As

Publication number Publication date
DK135723C (en) 1977-11-14
ES437099A1 (en) 1977-01-16
SU626706A3 (en) 1978-09-30
DE2445783A1 (en) 1975-04-03
NO140305B (en) 1979-04-30
PL92396B1 (en) 1977-04-30
GB1450884A (en) 1976-09-29
IE39913L (en) 1975-03-26
FI53709C (en) 1978-07-10
AT337915B (en) 1977-07-25
ES430369A1 (en) 1976-09-16
ES437101A1 (en) 1977-01-16
CH601352A5 (en) 1978-07-14
HU172656B (en) 1978-11-28
IL45483A (en) 1977-12-30
DK504574A (en) 1975-06-02
CA1025435A (en) 1978-01-31
IE39913B1 (en) 1979-01-31
SU612637A3 (en) 1978-06-25
BE820303A (en) 1975-03-25
FR2244497B1 (en) 1977-11-04
FR2244497A1 (en) 1975-04-18
FI276674A (en) 1975-03-27
NO140305C (en) 1979-08-08
FI53709B (en) 1978-03-31
SE7411948L (en) 1975-03-27
US3920703A (en) 1975-11-18
NO743467L (en) 1975-04-28
AR207230A1 (en) 1976-09-22
ZA745197B (en) 1975-09-24
ATA771874A (en) 1976-11-15
LU70980A1 (en) 1976-08-19
DK135723B (en) 1977-06-13
PL94256B1 (en) 1977-07-30
NL7411617A (en) 1975-04-01
AU7247974A (en) 1976-02-19
EG11189A (en) 1977-01-31
AR206632A1 (en) 1976-08-06
DD115492A5 (en) 1975-10-05
CS178930B2 (en) 1977-10-31
JPS5058054A (en) 1975-05-20
PH10616A (en) 1977-07-19
IL45483A0 (en) 1974-11-29

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