ES436233A2 - Derivatives of substituted tetrahydro-m-oxazines - Google Patents

Derivatives of substituted tetrahydro-m-oxazines

Info

Publication number
ES436233A2
ES436233A2 ES436233A ES436233A ES436233A2 ES 436233 A2 ES436233 A2 ES 436233A2 ES 436233 A ES436233 A ES 436233A ES 436233 A ES436233 A ES 436233A ES 436233 A2 ES436233 A2 ES 436233A2
Authority
ES
Spain
Prior art keywords
formula
derivatives
oxazines
choh
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES436233A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of ES436233A2 publication Critical patent/ES436233A2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/061,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/081,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Improvements introduced in the object of the main patent No. 402,400 filed on May 5, 1972, for: "Procedure for the preparation of new derivatives of substituted tetrahydro-m-oxazines", according to which when said derivatives respond to the following general formula: ** (See formula) ** where Ar is a phenyl nucleus substituted with one or two halogen atoms chosen from chlorine and fluorine, or with one or two alcohol radicals comprising a maximum of four carbon atoms, or with one or two methoxy groups, or with a radical chosen from among the following: trifluoromethyl, benzyloxy, and methylcarbonylamino; These improvements consist of condensing an amino alcohol of formula (II): Ar - 0 - CH2 - CHOH - CH2 - CH2 - NH2 (II) with thiophosgene of formula (III): CS CL2 (III) to give a hydroxylated isothiocyanate of formula (IV): Ar - O - CH2 - CHOH - CH2 - CH2 - N = C = S (IV) which then cyclizes; Ar in formulas (II) and (IV) having the same meaning as in formula (I). (Machine-translation by Google Translate, not legally binding)
ES436233A 1974-04-09 1975-04-02 Derivatives of substituted tetrahydro-m-oxazines Expired ES436233A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7412388A FR2269950B2 (en) 1974-04-09 1974-04-09

Publications (1)

Publication Number Publication Date
ES436233A2 true ES436233A2 (en) 1977-03-01

Family

ID=9137438

Family Applications (1)

Application Number Title Priority Date Filing Date
ES436233A Expired ES436233A2 (en) 1974-04-09 1975-04-02 Derivatives of substituted tetrahydro-m-oxazines

Country Status (11)

Country Link
JP (1) JPS50142523A (en)
BE (1) BE827650R (en)
CA (1) CA1064033A (en)
CH (1) CH568997A5 (en)
DE (1) DE2513229A1 (en)
ES (1) ES436233A2 (en)
FR (1) FR2269950B2 (en)
GB (1) GB1445324A (en)
IT (1) IT1044488B (en)
LU (1) LU72236A1 (en)
NL (1) NL7504192A (en)

Also Published As

Publication number Publication date
GB1445324A (en) 1976-08-11
CH568997A5 (en) 1975-11-14
LU72236A1 (en) 1976-03-02
FR2269950B2 (en) 1978-07-28
IT1044488B (en) 1980-03-20
DE2513229A1 (en) 1975-10-30
JPS50142523A (en) 1975-11-17
CA1064033A (en) 1979-10-09
NL7504192A (en) 1975-10-13
FR2269950A2 (en) 1975-12-05
BE827650R (en) 1975-10-07

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170705