ES432699A2 - Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES432699A2 ES432699A2 ES432699A ES432699A ES432699A2 ES 432699 A2 ES432699 A2 ES 432699A2 ES 432699 A ES432699 A ES 432699A ES 432699 A ES432699 A ES 432699A ES 432699 A2 ES432699 A2 ES 432699A2
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- radical
- signifies
- group
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Abstract
Improvements introduced in the object of the main patent No. 419,607, applied for on October 13, 1973, by "Procedure for the preparation of new benzylamines", said improvements referring to the preparation of benzylamines of the general formula I **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where it means a hydrogen atom, a hydroxyl group or an alcohol group with 1 to 4 carbon atoms, n means the number 0, 1 or 2, and the two radicals A and B mean hydrogen atoms or together the group **(See formula)** Wherein represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m represents the number 1 or 2, R4 means a straight-chain or branched alcohol radical with 1 to 4 carbon atoms, an alkenyl radical with 2 to 4 carbon atoms, a cycloalkyl radical with 3 or 4 carbon atoms or also a hydrogen atom, in case R3 does not represent a hydrogen atom or represents a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted by 1 to 3 hydroxyl groups, and 1 means the number 1 or 2, as well as their physiologically tolerable acid addition salts with inorganic or organic acids, characterized in that a compounds of the general formula II, **(See formula)** in which R1, Hal and I are as defined at the beginning and R6 signifies an amino group, which may optionally be monosubstituted or disubstituted, a trialkohylammonium or pyridinium radical, is reacted with an amine of the general formula III **(See formula)** wherein R2 and R4 are as defined at the beginning, and a compound of the general formula I, obtained if so desired, is then transformed into its physiologically tolerable acid addition salts with inorganic acids or organic. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19722251891 DE2251891C3 (en) | 1972-10-23 | Benzylamines, their physiologically acceptable salts, processes for their preparation and pharmaceuticals containing them | |
DE2316325A DE2316325A1 (en) | 1972-10-23 | 1973-04-02 | Halo-hydroxy-substd-benzylamines - as secretolytic and antitussive agents |
DE19732320967 DE2320967C3 (en) | 1973-04-26 | New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them | |
ES419607A ES419607A1 (en) | 1972-10-23 | 1973-10-13 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES432699A2 true ES432699A2 (en) | 1977-07-01 |
Family
ID=27184783
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES419607A Expired ES419607A1 (en) | 1972-10-23 | 1973-10-13 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES423970A Expired ES423970A1 (en) | 1972-10-23 | 1974-03-16 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES432699A Expired ES432699A2 (en) | 1972-10-23 | 1974-12-07 | Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES419607A Expired ES419607A1 (en) | 1972-10-23 | 1973-10-13 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES423970A Expired ES423970A1 (en) | 1972-10-23 | 1974-03-16 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (3) | ES419607A1 (en) |
-
1973
- 1973-10-13 ES ES419607A patent/ES419607A1/en not_active Expired
-
1974
- 1974-03-16 ES ES423970A patent/ES423970A1/en not_active Expired
- 1974-12-07 ES ES432699A patent/ES432699A2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES419607A1 (en) | 1976-06-16 |
ES423970A1 (en) | 1976-07-01 |
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