ES431320A1 - Process for the manufacutre of 6-d- - x-aminophenylacetamido- pencillanic acid - Google Patents
Process for the manufacutre of 6-d- - x-aminophenylacetamido- pencillanic acidInfo
- Publication number
- ES431320A1 ES431320A1 ES431320A ES431320A ES431320A1 ES 431320 A1 ES431320 A1 ES 431320A1 ES 431320 A ES431320 A ES 431320A ES 431320 A ES431320 A ES 431320A ES 431320 A1 ES431320 A1 ES 431320A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- formula
- aminophenylacetamido
- see formula
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Process for the manufacture of 6- [D (-) - alpha-aminophenylacetamido] -penicillanic acid, of formula I **(See formula)** characterized by comprising: a) the condensation of 6-aminopenicillanic acid of formula II **(See formula)** with a substituted D-phenylglycine of the general formula III **(See formula)** in which R1 signifies a 2- (1-carbalkoxy) -propenyl group, a 2- (1-alkylcarbonyl) -propenyl group or a hydrogen atom, R2 means an oxycarbetoxy group, an oxyacyl group, a cyanomethylene group, a p-nitrophenyl group, a 2,4,5-trichlorophenyl group or a halogen atom, R1 and R2, taken together, form an oxycarbonyl group, b) extraction with chlorinated hydrocarbons of 1 to 2 carbon atoms and 1 to 3 chlorine atoms, and c) treatment with primary or secondary aliphatic alcohols of 1 to 4 carbon atoms. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU280473A YU36733B (en) | 1973-10-26 | 1973-10-26 | Process for preparing pure anhydrous 6-zd-(-)-alfa-aminophenylacetamidoc-penicillanic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
ES431320A1 true ES431320A1 (en) | 1976-10-16 |
Family
ID=25558789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES431320A Expired ES431320A1 (en) | 1973-10-26 | 1974-10-24 | Process for the manufacutre of 6-d- - x-aminophenylacetamido- pencillanic acid |
Country Status (5)
Country | Link |
---|---|
DE (1) | DE2450661A1 (en) |
ES (1) | ES431320A1 (en) |
GB (1) | GB1442920A (en) |
KE (1) | KE2800A (en) |
YU (1) | YU36733B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL162387C (en) * | 1977-09-06 | 1980-05-16 | Gist Brocades Nv | PROCESS FOR PREPARING 6- (D-ALPHA-AMINO-P- HYDROXYPHENYLACETAMIDO) PENICILLANIC ACID. |
GB2240102B (en) * | 1990-01-22 | 1993-10-20 | Biochemie Gmbh | Improvements in or relating to beta lactam production |
CN106520893B (en) * | 2016-11-04 | 2021-05-04 | 内蒙古常盛制药有限公司 | Method for preparing ampicillin from penicillin potassium |
-
1973
- 1973-10-26 YU YU280473A patent/YU36733B/en unknown
-
1974
- 1974-10-22 GB GB4569674A patent/GB1442920A/en not_active Expired
- 1974-10-24 DE DE19742450661 patent/DE2450661A1/en active Pending
- 1974-10-24 ES ES431320A patent/ES431320A1/en not_active Expired
-
1977
- 1977-11-24 KE KE280077A patent/KE2800A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU7452574A (en) | 1976-04-29 |
GB1442920A (en) | 1976-07-14 |
YU280473A (en) | 1982-06-18 |
YU36733B (en) | 1984-08-31 |
DE2450661A1 (en) | 1975-04-30 |
KE2800A (en) | 1978-01-06 |
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